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Gustavo Fonseca, MD, FACP, physician director of clinical research, Florida Cancer Specialists & Research Institute (FCS), discusses the results from a late phase complexity analysis on barriers to clinical trials regarding biopsy requirements.

The study also found people with vitamin D deficiency had a lower mortality rate from Clostridioides difficile infection (CDI).

Patients with non-small cell lung cancer (NSCLC) with a high risk of brain metastases might feasibly be identified through machine-learning models, according to a recent study.

The FDA companion diagnostic designation for FoundationOne CDx may improve access to niraparib/abiraterone acetate for eligible patients with metastatic castration-resistant prostate cancer (mCRPC) harboring a BRCA mutation.

Researchers determined that the Huber et al. criteria regarding prostate-specific antigen (PSA) levels may more accurately predict the need for additional treatment or the possibility of treatment failure compared with other PSA-based definitions.

This rare adverse effect was witnessed in a small number of people post vaccine administration.

In this multicenter cohort study, COVID-19 vaccination at any gestational stage improved antibody responses for pregnant individuals and their infants. Booster vaccine recipients demonstrated increased benefits in these effects at delivery.

Delays in time to treatment initiation may be associated with demographic and socioeconomic disparities, with care coordination, clinical, and socioeconomic factors representing potential predictors of time to treatment initiation.

The European Medicines Agency (EMA) has accepted a Marketing Authorization Application (MAA) for odronextamab for relapsed/refractory (R/R) follicular lymphoma (FL) or R/R diffuse large B-cell lymphoma (DLBCL) following disease progression after at least 2 prior lines of systemic therapy.

The revisions to the ACO REACH model are expected to add predictability and stability while advancing health equity.

Researchers found that patients with chronic obstructive pulmonary disorder (COPD) with higher Systemic Immune-Inflammation Index (SII) levels have a greater risk of all-cause mortality.

Even patients with diffuse large B-cell lymphoma who are eligible for chimeric antigen receptor (CAR) T-cell therapy face multiple barriers to care and need assistance.

Despite receiving their diagnosis at a younger average age, Hispanic or Latino patients paradoxically have the lowest incidence of recent breast cancer screenings prior to diagnosis.

The targeted therapy already has indications in acute myeloid leukemia.

A small study suggests the use of anti-CD19 chimeric antigen receptor (CAR) T-cell therapy in patients with mantle cell lymphoma (MCL) with secondary central nervous system (CNS) involvement is safe and effective.

A new CMS proposal would authorize Medicare payments to cover family caregiver training; US list prices for popular weight loss drugs are higher than those of other wealthy nations; Midwestern cities declare themselves sanctuary cities despite anti-LGBT state laws passed.

Palivizumab may be well tolerated and effective in the prevention of serious respiratory symptoms due to infection with respiratory syncytial virus (RSV).

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Researchers analyzed numerous biomarkers in patients at risk for inflammatory arthritis to develop measurable scores indicating a patient's vulnerability to disease progression.

The researchers found that methods of physical activity data collection and processing for patients with interstitial lung disease (ILD) were difficult to interpret and to compare with other disease states.

“Our study suggests that narrowly focusing on hospital volumes and tying that to insurance reimbursement might mask complexities and trade-offs in achieving the goal of optimizing patient outcomes and experiences,” lead co-author Lindsay Sabik, PhD, says.

Patients with RET fusion-positive advanced or metastatic non–small cell lung cancer had a survival benefit when treated with selpercatinib in the LIBRETTO-431 study.

Stroke of an undetermined cause was associated with acute symptomatic seizures, an effect that was marginally mediated by cerebral microbleeds.

The decrease in e-cigarette use between 2014 and 2019 may be linked to improved education on the harms of the devices, while the increase in 2019 could be attributed to worsened psychological burden during the COVID-19 pandemic.

A recent study found that children who had private insurance had a higher probability of vision testing compared with uninsured and publicly insured children.

Trends show rising rates of cancers among young adults; The Physicians Foundation launches program to address social determinants of health; Blue Shield California drops CVS health

Standardized reporting of patient adherence and engagement among digital health interventions for depression offers more effective comparisons between digital health tools and populations.

This study compared autoantigen detection of acetylcholine receptor and muscle-specific kinase, among 3 assays used in suspected cases of myasthenia gravis.

In this interview, Catherine Nester, RN explains the importance of entering phase 2 of the whole genome sequencing newborn screening program.

Patients with uncontrolled asthma had reduced symptoms and exacerbations with tezepelumab, according to a new study.