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The National Institute of Allergy and Infectious Diseases, the World Health Organization, and the Congolese government announced that 2 experimental antibody-based treatments for Ebola are working so well that they will now be offered to all patients in the Democratic Republic of Congo; enrollment in insurance exchanges under the Affordable Care Act remains stable for people with lower incomes who received subsidies, but premium increases caused a 24% decline for people who did not qualify for assistance; scientists are repurposing old drugs or combining them with traditional antibiotics in an effort to combat antibiotic-resistant bacteria.

As disruptive medical technologies emerge, often unanticipated, bioethical issues arise, presenting challenges for employers navigating what benefits to offer to their employees.

Using data from 330 millennials responding to an online survey in December 2018, a Welltok survey revealed that 78% of the age group feel that employers are not doing enough to support their well-being.

Implementing a comprehensive social determinants of health program and addressing the root causes of medication nonadherence could mean the difference between a 3- and 4-star rating in Medicare Advantage.

As our country continues its push to lower the cost of healthcare, especially among the burgeoning population of seniors with age-related disabilities, transitioning to a value-based insurance design payment model that rewards value, rather than quantity, will become progressively more important. In the realms of musculoskeletal pain and movement dysfunction, this transition must be accompanied with sincere efforts to identify treatments that can effectively manage pain and reduce the total cost of care.

The Department of Homeland Security said that it was promoting the ideals of self-sufficiency, self-reliance, industriousness, and perseverance, but it also acknowledged that the vast majority of the 266,000-plus commenters on the rule opposed the change and noted that some people may decide to drop out of benefit programs.

New research is suggesting that measuring the pulse wave at a menopausal woman’s wrist may explain the increase in cardiovascular disease risk during menopause better than a standard blood pressure measurement.

A class-action trial begins Monday in Hartford, Connecticut seeking to end Medicare regulations around something called “observation care” in the hospital; California hospitals are providing significantly less free and discounted care to low-income patients because the Affordable Care Act reduced the number of uninsured patients; The American Academy of Pediatrics released its first policy statement about how racism affects the health and development of children and adolescents.

“Our data suggest that people with central obesity, insulin resistance, and active psoriasis are the most at risk for liver fibrosis,” wrote the authors, and “if use of methotrexate is a risk factor, it is not the only risk factor and for most patients it is unlikely to be the most important risk factor.”

The clinical manifestations of symptoms experienced by children and adolescents with narcolepsy can differ from those seen in adults, presenting barriers to a timely diagnosis.

A screening test could be used in clinical trials on prevention of the disease.

As survival rates for malignant melanoma increase, so does the likelihood that some patients will develop second primary cancers.

The clinical features of systemic inflammation in chronic obstructive pulmonary disease (COPD) are well recognized, but little is understood about the molecular mechanisms underlying this inflammation.

Patients with monoclonal gammopathy of undetermined significance (MGUS), a precursor to multiple myeloma (MM), can progress from low- or intermediate-risk to MM in just 5 years, according to researchers who are now recommending all patients with MGUS undergo blood testing and risk assessment.

The authors said their study shows that implementing migraine guidelines into day-to-day clinical practice needs improvement.

The survey aimed to better understand the perceptions, experiences, and educational needs of patients who have nonmotor symptoms of Parkinson disease as well as their caregivers.

Providers are using outdated practices to connect with patients for their bills.

Obstructive sleep apnea, a catalyst for higher rates of depression, is a factor in the failure of major depressive disorder treatment, according to a June study published in The Journal of Psychiatric Research.

A recent review of biomarkers of subclinical atherosclerosis in patients with psoriatic arthritis (PsA) showed more severe atherosclerotic disease compared with patients who have only psoriasis.

Asthma adversely affects the everyday lives of many individuals regardless of long-term maintenance medication, according to a study evaluating the association of time spent at work and adverse asthma effects.

The study found that 24% of those who contacted a center specializing in rare kidney diseases would have gone undiagnosed if they had not reached out directly via the center's website.

People who have better cardiovascular health, as scored by the American Heart Association's Life's Simple 7, at age 50 have a lower risk of developing dementia over the next 25 years, according to a new study.

In the 5 years before being diagnosed, patients with multiple sclerosis (MS) were less likely to receive vaccinations than comparator groups, according to a new study from the Technical University of Munich and published in Neurology.

Mistrust in healthcare can have big repercussions and can perpetuate ongoing health disparities. Here are 5 things about medical mistrust.

This week, the top managed care stories included CMS giving chimeric antigen receptor T-cell payments a boost; a US task force announcing that those at risk for pancreatic cancer should be screened; FDA revealing Novartis withheld data about a high-cost gene therapy.

A new understanding of how poly (ADP ribose) polymerase (PARP) inhibitors work could expand the patient populations who are treated, according to a study. The researchers also identified a potential biomarker to indicate which patients would benefit the most.

Researchers found that they were able to use a small molecule called ZL0580 to modify bromodomain-containing protein 4 to suppress HIV.

The FDA ordered 4 companies to stop selling 44 of their flavored e-liquid and hookah tobacco products that lack the required approval for sale; CMS has yet to implement a 2014 law preventing unnecessary, expensive screening tests (magnetic resonance imaging, computed tomagraphy scans and other tests) that could harm patients and waste resources; Amarin, which is seeking FDA approval for an expansion of Vascepa labeling to include data that showed a 25% reduction in the risk of heart attacks and strokes, said the FDA has scheduled an advisory committee meeting for November 14.

Results of this study suggest dosing for vaccines should be adjusted based on age and gender of the patient.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.