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Real-world patients with moderate-to-severe psoriasis were shown to exhibit impaired efficacy with guselkumab treatment if they had history of prior biologic use, particularly anti-interleukin (IL)-17 exposure, with heavier patients linked with delayed onset of therapeutic response.

Researchers in Japan identified 2 potential biomarkers for severity of pulmonary arterial hypertension (PAH) that can be measured without invasive procedures.

Studies presented at the American Society of Ophthalmic Plastic & Reconstructive Surgery 2021 Fall Scientific Symposium explored the impact of lower dose rituximab on orbital lymphoma and factors associated with survival in conjunctival lymphoma.

Biological markers collected early in the disease course of rheumatoid arthritis could help improve patient management, researchers said.

Uveitic macular edema is common in patients with noninfectious uveitis, and its significant burden on patients and payers warrants more specific treatment guidelines to minimize quality-of-life and economic effects.

Results of a phase 4 study show erenumab to be superior in efficacy and tolerability outcomes among migraineurs compared with topiramate.

Leslie Kantor, PhD, MPH, chair and professor of the Department of Urban-Global Public Health, Rutgers School of Public Health, discusses the key messages that people need to hear about the continued importance of the flu vaccine, even if they have been immunized for COVID-19.

California is offering COVID-19 boosters to its entire adult population; FDA recalls millions of home COVID-19 tests over false positives; veterans’ access to health resources will be expanded.

Recent research from the United Kingdom sought to understand more about factors that may impact the location of death for patients with Parkinson disease (PD) and multiple sclerosis (MS).

Researchers conducted the study because although prior research has illustrated that elevated levels of iron in the blood from hereditary hemochromatosis can raise the risk of liver cancer, little is known about the effect of this condition in nonalcoholic fatty liver disease (NAFLD).

Solutions for health equity, treatments for heart failure, and the use of technology in prevention and patient care are just some of the topics on the agenda for the 2021 American Heart Association (AHA) Scientific Sessions, which will take place Saturday through Monday in a virtual format.

At the American Society of Ophthalmic Plastic & Reconstructive Surgery's 2021 Fall Scientific Symposium, presentations on orbital complications included research on poorly positioned implants and factors associated with orbital compartment syndrome.

Because treatment with growth hormone (GH), often necessitated by GH deficiency from childhood cancer, has been linked to tumorigenesis, concerns remain around its use among childhood cancer survivors.

Data on nusinersen’s safety profile in adult patients are more limited than in infant and adolescent patients, but a recent study showed positive results based on cerebrospinal fluid and blood sample parameters.

Robert A. Gabbay, MD, PhD, chief scientific and medical officer at the American Diabetes Association, explains why clinical trials need to be inclusive and how the Health Equity Now initiative is working to recruit more diverse populations with diabetes.

Across all studies included, observed-to-expected ratios showed that White and Asian patients were overrepresented while Black patients, Hispanic patients, and American Indian/Alaskan Native patients were underrepresented.

Theresa Juday, RPh, director, Specialty Product Development, CVS Health, speaks about the barriers affecting uptake of cognitive behavioral therapy (CBT) as a first-line treatment for insomnia.

Seth Martin, MD, MHS, associate professor of medicine at Johns Hopkins University and co-director of the Center for Mobile Technologies to Achieve Equity in Cardiovascular Health (mTECH Center), gives a preview of his presentation on digital divides at the American Heart Association (AHA) Scientific Sessions 2021.

Study findings presented at the American Society of Ophthalmic Plastic & Reconstructive Surgery's 2021 Fall Scientific Symposium detail the benefits of teprotumumab for thyroid eye disease.

The World Health Organization and CDC warn of the potential for measles outbreaks; the National Institutes of Health (NIH) and Moderna battle over patent rights to Moderna’s COVID-19 vaccine; a new Kaiser Family Foundation shows employers have increased mental health care offerings.

Although the authors say their findings shed light on possible disruptions to insulin supply during COVID-19, they note they could not adjust for those with diabetes who died.

Michael E. Chernew, PhD, co-editor-in-chief of The American Journal of Managed Care®, discussed cost and sustainability issues specific to commercial insurance, Medicare, and Medicaid at the National Alliance 2021 Annual Forum held in a hybrid format in Washington, DC.

States are turning to alternative payment models to improve outcomes and reduce health care expenditures, representing a critical step forward specifically for the US maternal health crisis.

A recent review highlighted the importance of managing cardiovascular risk factors in patients with Fabry disease versus the general population.

A recent review examined the significant physical, social, emotional, and financial impacts of acid sphingomyelinase deficiency (ASMD) on patients and caregivers from an overall lifestyle standpoint

Drug use, serum albumin, and total number of lesions may serve as independent factors influencing the degree of disability in patients with multiple sclerosis (MS), investigators of a retrospective analysis concluded.

Access to antiretroviral treatment was not disrupted, despite decreased in-person services during the pandemic.

The share of patients meeting the definition of polypharmacy for the condition of overactive bladder declined from 2006 to 2017, but the phenomenon was still prevalent in women and patients in nursing homes, according to a recent study.

Adults with atopic dermatitis were shown to be at lower risk of developing asthma if they were vaccinated against influenza, particularly those who adhered to yearly shots.

Robert A. Gabbay, MD, PhD, chief scientific and medical officer at the American Diabetes Association, discusses COVID-19 vaccinations among people with diabetes as they have been disproportionally affected by the pandemic.