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Research from the Dana-Farber Cancer Institute and the Broad Institute, published in Nature, has identified genomic changes that could explain the development of testicular cancer and why this disease is more responsive to chemotherapy.

In a show of bipartisanship, the House of Representatives overwhelmingly passed the 21st Century Cures Act on November 30 by a vote of 392-26. Here are 5 things to know about the legislation.

A review of our peer-reviewed research in the healthcare and mainstream press.

This week, the top stories in managed care included the president-elect's picks for HHS and CMS, the American Diabetes Association addressed psychosocial care for patients with diabetes, and the American Society of Clinical Oncology released criteria on creating clinical pathways.

The physicians said the American Medical Association abandoned a core mission of protecting patients by endorsing a nominee who wants to roll back Medicaid expansion and privatize Medicare.

The CDC has now published the Core Elements of Outpatient Antibiotic Stewardship in the Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports, to provide guidance for antibiotic stewardship in outpatient settings.

An analysis of 150 US cities’ stress rankings and the CMS star ratings of the hospitals within them reveals a significant correlation between the 2 factors, indicating that more-stressed cities tend to have lower hospital star ratings.

Interim data analysis of a phase 1 trial of chimeric antigen receptor-T cells (CAR-T) targeting the B-cell maturation antigen in heavily pretreated patients with multiple myeloma has identified an objective anti-tumor response, with limited toxicity.

The study found that avoiding 3 key risk factors-diabetes, obesity, and hypertension-by age 45, greatly increased the likelihood of avoiding heart failure through the end of life.

The National Center for Complex Health and Social Needs was launched to create a space for innovators to work together to identify the best evidence-based models for improving care for the relatively small population of patients with complex health and social needs that drives a disproportionate share of our healthcare costs.

What we’re reading, December 1, 2016: the percentage of Republicans that would like to see the Affordable Care Act scaled back instead of repealed has more than doubled since the election; smoking will soon be prohibited in all public housing nationwide; some physicians are incensed by the American Medical Association’s support for Rep. Tom Price as HHS secretary.

The House of Representatives has approved the bipartisan 21st Century Cures legislation, which includes funding for innovative biomedical research and provisions to speed up the drug approval process.

Statin use was associated with a reduction in all-cause and multiple myeloma-specific mortality.

The study found young adults had the lowest device uptake, as well as highest distress levels and the highest A1C.

The House Energy and Commerce Committee's subcommittee on health will gather testimonial from leaders of the US Preventive Services Task Force, the American Academy of Family Physicians, and the American Urologic Association, on a bill called H.R. 1151.

The amount of Americans under age 65 in families having trouble paying medical bills has dropped significantly over the past 5 years, according to a survey report from the National Center for Health Statistics. The percentage of children in families that struggle to pay healthcare bills has steadily declined as well, though as of June 2016 it remained higher than the percentage of such adults.

Though they may not directly provide patient care for their members, managed care organizations (MCOs) play a substantial role in the patient experience of millions of Medicaid enrollees.

There has been increased bipartisan support around the expanded role of value-based insurance design.

What we’re reading, November 30, 2016: the FDA agrees to clinical trials of Ecstasy to treat posttraumatic stress disorder; University of Pittsburgh Medical Center workers strike to protest wages and union rights; a New York pharmacy owner will spend 4 years in jail for distributing 500,000 oxycodone pills without prescriptions.

A nationally representative study among patients enrolled in Medicare, who were diagnosed with cancer, found that out-of-pocket costs averaged at 23.7% of their household income. A majority of these costs could be attributed to hospitalization.

In New Jersey, a group of business and labor leaders-along with the state's largest health plan-decided it was time for the term "patient-centered" to be understood by a key constituency: patients themselves.

Community coalitions are a backbone of public health, and offer a unique perspective towards implementation of managed care disease management/case management programs.

The proposal from CMS may make it difficult for groups that have been providing the DPP to take part in Medicare reimbursement.

The American Society of Clinical Oncology (ASCO) has released the Criteria for High-Quality Clinical Pathways in Oncology, which is expected to help providers assess the quality, utility, and integrity of pathway programs in the United States.

Early results published Tuesday were first presented this summer at the meeting of the American Diabetes Association.

What we're reading, November 29, 2016: Warren cries foul over pharma's role in legislation; women fear what will happen to coverage under Trump; and Gallup poll finds most Americans want changes or repeal of the Affordable Care Act.

The Georgia Congressman is a longtime critic of the Affordable Care Act.

Awareness of Medicaid eligibility rules meant that in 2014 alone, more than 2 million people enrolled for benefits who belonged in the program but for some reason had never signed up.

With $372 million carved out for the National Institutes of Health innovation account in 2017, and about $114 million assigned to President Barack Obama’s Precision Medicine Initiative for the fiscal year 2018, the 21st Century Cures Act has a lot at stake for healthcare in the United States.

Patients who received care for their chronic diseases in a patient-centered medical home had higher rates of medication adherence over 12 months than patients treated elsewhere, according to a study in the Annals of Internal Medicine.