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While the FDA’s approval of the immunotherapy tisagenlecleucel represents a landmark in the oncology field, the treatment is far from being a cure and should be viewed in context of its $475,000 price tag, a group of oncologists wrote in a commentary published in JAMA.

The FDA has rejected an abuse-deterrent opioid citing the need for further evidence. Rexista, an Oxycodone Hydrochloride Extended-Release tablet (Oxycodone ER), was developed by Intellipharmaceutics International Inc as an abuse- and alcohol-deterrent controlled-release oral formulation of oxycodone hydrochloride for pain relief.

Researchers at the London School of Economics and Political Science have developed a multiple criteria decision analysis model, The Advance Value Framework, that payers can utilize for evaluating new medicines that come to the market.

A new study finds that participating in the Supplemental Nutrition Assistance Program (SNAP) is associated with significantly lower healthcare expenditures, pointing to the role of social determinants like food insecurity as contributors to health spending.

The move to give entrepreneurs access to patient-approved continuous glucose monitoring data fits with the company's prediction that insulin pumps will become a thing of the past, and most of the heavy lifting of delivery will be done by a smartphone.

The increasing trend in long-term prescription opioid use in the United States calls for further research on the potential benefits and harm, according to a study.

There is a dimensional relationship that links white matter structure to neurodevelopmental symptoms, such as those associated with autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD). However, more research on the connection is necessary.

Neighborhood disadvantage may be an important determinant of the risks of major atherosclerotic cardiovascular disease (ASCVD)—related events, according to a new study.

Outcomes-based pricing arrangements for pharmaceuticals are increasingly popular. In this piece, we discuss the impact of the outcomes-based pricing arrangements proposed by Amgen on the pricing of PCSK9 inhibitor therapy, and we provide recommendations for payers on the design of outcomes-based contracts.

When immune-related adverse events arise from nivolumab, it may indicate that the therapy is having greater efficacy against non—small-cell lung cancer (NSCLC), as a new study demonstrates a link between these events and improved survival outcomes.

Greater levels of physical activity are associated with a decreased risk of mortality and cardiovascular disease events in low-, middle-, and high-income countries.

A new paper in JCO Precision Oncology evaluated the impact of the support provided by a decision support team on clinical decision making and trial enrollment.

Patients using secure online messaging to communicate with their healthcare providers about their type 2 diabetes (T2D) demonstrated improved clinical outcomes, according to a new study.

This week, the top managed care stories included a new direction for the Center for Medicare and Medicaid Innovation; a bipartisan group of governors spoke out against the latest effort to repeal the Affordable Care Act; and the World Health Organization warned that antibiotics currently being developed were not enough to fight antibiotic-resistant infections.

The legislation known as Graham-Cassidy represents the last chance to repeal the Affordable Care Act. Here are 5 components that make it different from other proposed repeal bills.

In their letter, the directors said the bill would result in "the largest intergovernmental transfer of financial risk from the federal government to the states in our country’s history."

Coverage of our peer-reviewed research in the healthcare and mainstream press.

More work is needed to understand the connections between premature births and birth defects, researchers said.

Authors of the study say the technology exists to screen seniors with type 2 diabetes and identify those at risk of a fracture.

Occupations related to potential noxious airborne agents are related to an increased risk of rheumatoid arthritis (RA), according to recent research.

Childhood-onset inflammatory bowel disease (IBD) is known to cause painful gastrointestinal symptoms, but a new study of Swedish patients finds that it is also associated with an increased risk of cancer.

What hurricanes and floods reveal about the shortcomings in value-based care policy.

A new review article published in the New England Journal of Medicine explores the recent developments in radiotherapy that have improved survival and quality of life for patients with cancer.

Research shows consumers expect to pay for healthcare in multiple ways, including through their smartphone. Failure to meet consumer demands will affect healthcare's bottom line.

Physicians across different institutes who have been involved in clinical trials of chimeric antigen receptor (CAR) T cells in B-cell lymphomas have developed a guideline for monitoring and managing the symptoms associated with this treatment.

CMS has issued an informal request for information seeking input on a new direction promoting patient-centered care and market-driven reforms for the CMS Innovation Center.

Federally qualified health centers face significant financial and competitive pressures, but executives reported in a recent survey that they have identified areas for improvement and are planning a path to success.

Truck drivers were identified in a Gallup survey as the profession most at risk for type 2 diabetes.