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Despite recent setbacks, drug makers and investors are still optimistic about finding an Alzheimer disease treatment; the United States' already moderately severe flu season could get worse; a charity that assists patients with out-of-pocket drug costs is suing the government over communication restrictions with drug donors.

Dry eye was found to be a comorbid pain condition among US veterans, raising the suggestion that pain specialists screen for this disorder in their chronic pain patients, researchers reported recently.

The study confirms reports heard throughout the country in the years since implementation of the Affordable Care Act.

The approval will expand the currently approved indication for the prevention of skeletal-related events in patients with bone metastases from solid tumors to also include patients with multiple myeloma.

A new guideline from the American Psychiatric Association to treat alcohol use disorder focuses on the use of evidence-based pharmacological treatments.

CDC to hold workshop that prepares for a public health response to a nuclear detonation; hospitals face shortage of intravenous bags after Hurricane Maria damages production in Puerto Rico; Idaho's governor signs executive order to loosen the Affordable Care Act's rules on health coverage requirements.

A subset of patients with chronic lymphocytic leukemia (CLL) with highly expressed CD49d have poorer outcomes while on Bruton’s tyrosine kinase (BTK) inhibitor ibrutinib, which antagonizes B-cell receptor (BCR) signals. However, a team of researchers may have found a way to treat these patients.

Although an additional one-time screening at any age between 15 and 30 yields important gains in HIV diagnosis rates and life expectancy for HIV-infected people, screening at age 25 would provide the most favorable clinical outcomes and the best value for money, according to a study in the Journal of Adolescent Health.

New drugs to treat multiple myeloma (MM) have provided clinical benefits, but a study published in the Journal of Managed Care & Specialty Pharmacy found not all of them can be considered cost effective.

As health IT continues to have a growing impact, new draft guidances, regulations, and innovations have been introduced to better enhance interoperability and the healthcare experience for both providers and patients. The arrival of 2018 brought multiple updates in health IT that will likely have lasting implications.

The factory-calibrated continuous glucose monitoring (CGM) system is being touted as less expensive, and a spokeswoman said it will not require bundling with a meter, which is required for a competitor.

Several studies have suggested that inflammation plays a role in Huntington disease (HD), and a recent review, published in Neural Regeneration Research, explored the anti-inflammatory and immunomodulatory agents that have been investigated as possible treatments for HD.

Draft framework from the Office of the National Coordinator on Health IT seeks to build a single on-ramp to advance interoperability in the United States through the Trusted Exchange Framework.

This week, the top managed care stories included an analysis of how healthcare spending has changed in the United States; a study finds people willing to try e-cigarettes smoke less and are more likely to quit; and a new cholesterol test that doesn't require fasting gives more accurate results.

While chemotherapy with thoracic radiation has been established as the standard of care for the initial treatment of non-metastatic small-cell lung cancer, a large proportion of patients do not receive these treatments and in turn have lower overall survival, according to a study published in JAMA Oncology.

New legislation in California would aim to curb opioid addiction; increasing number of generics are causing medicines to be more affordable; healthcarey company focused on serving low-income urban residents receives first round funding.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

What's in store for the 2018 healthcare landscape? The buzzwords for the year include flexibility, innovation, and data across a number of areas.

In the inpatient setting, access to electronic health records (EHRs) through patient portal use remains low, according to a study published in the Journal of the American Medical Informatics Association.

Dexcom Executive Vice President and Chief Commercial Officer RIck Doubleday visited The American Journal of Managed Care® to discuss Medicare reimbursement for the Dexcom G5 and a new partnership with Fitbit.

Both accountable care organizations (ACOs) and narrow networks are important components of the value-based care movement. However, while there are features common to both models, Catalyst for Payment Reform has learned that what constitutes ACOs and narrow networks is inconsistent across health plans.

Scientists have found a possible link between maternal cholesterol levels and the risk of attention-deficit-hyperactivity disorder (ADHD) in children, with boys being more susceptible to the effect than girls.

Researchers have made a key discovery that could pave the way to designing an improved opioid to relieve pain without the risk of addiction and side effects.

Credit rater predicts Obamacare insurers will have a relatively stable 2018; Buffalo, New York, has the country's first opioid court aimed at saving lives; ambulance rides are down in cities with Uber.

Adolescent and young adults with attention-deficit/hyperactivity disorder (ADHD) are at a higher risk for subsequent sexually transmitted infections (STIs), but taking medicine for ADHD can help cut the risk, according to research published in the Journal of the American Academy of Child and Adolescent Psychiatry.

The US Chinese aging population has experienced a rapid growth in recent years. However, research about the social networks of older immigrant adults has been lacking. That scarcity of information has led to a lack of understanding that has limited the ability of US healthcare professionals and policy makers to provide the best strategies to improve the health and wellbeing of older Chinese adults.

Since the implementation of the Affordable Care Act (ACA), annual well visits among adolescents improved with visits increasing the most among Hispanic adolescents.

A federal judge dismissed a move to block 340B cuts days before CMS’ final rule on it went into effect.

Carfilzomib was associated with higher rates of all-grade and high-grade cardiovascular adverse events (CVAE), and both later trial phase and higher doses of carfilzomib were associated with higher rates of CVAE, according to a study in JAMA Oncology.

A study comparing costs and death rates for veterans obtaining percutaneous coronary intervention (PCI) found that when the procedure was performed at a community facility versus one operated by the Veterans Administration, the veteran was more likely to die and the procedure itself was more expensive. However, death rates were similar for elective coronary artery bypass grafts.