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The study by the National Institute on Aging produced a few surprises and was stopped early when aspirin showed no benefit.

Patient and advocacy groups filed a lawsuit seeking to block the Trump administration’s plan to let people buy short-term health insurance that doesn’t comply with the Affordable Care Act; members of the federal Medicaid and CHIP Payment and Access Commission advisory panel expressed concerns that 4350 low-income people in Arkansas had lost Medicaid coverage because they failed to show they were complying with new work requirements; half as many people tried heroin for the first time in 2017 as in 2016, but marijuana use grew.

Children of Hispanic ethnicity have a higher risk of developing neurotoxicity when they are treated with methotrexate for acute lymphoblastic leukemia (ALL) compared with non-Hispanic white children.

There is an association between an individual’s perceptions of community safety and adverse respiratory health among populations with exposure to high air pollution, according to new research.

A National Comprehensive Cancer Network (NCCN) working group dedicated to analyzing current challenges under existing policy and treatment paradigms presented their findings and recommendations at an NCCN Policy Summit in Washington, DC.

As the term “value” has become a norm in healthcare, specifically in oncology, panelists at a National Comprehensive Cancer Network policy summit offered perspectives on where we are now in delivering high-quality cancer care under value-based payment models.

A 12-month, late-stage study of romosozumab in men aged 55 to 90 years with osteoporosis found that it increased spine and hip bone mineral density (BMD) and was well tolerated.

A recent study has discovered that B cells mediate spontaneous T cell proliferation through the HLA-DR15 haplotype, and this interaction between T cells and B cells may serve as a key factor in understanding the pathogenesis of multiple sclerosis (MS).

A descriptive, observational study in Switzerland implemented an interprofessional medication adherence program (IMAP) in patients with HIV. The framework for the implementation of services in pharmacy (FISpH) model is described and formulated for other healthcare facilities and professionals to evaluate and execute for themselves.

A recent report from the National Comprehensive Cancer Network (NCCN) investigated the current state of chimeric antigen receptor (CAR) T-cell therapy and future strategies to consider as the novel immunotherapy evolves and is used in the treatment of more patients.

Research has shown nonemergency medical transportation can be essential for patients in rural areas, as well as the poor, elderly, and chronically ill. In a Health Affairs blog post, authors from CareMore Health show how the company has found success with Lyft after a pilot program it ran in 2016.

A recent study has found that prolonged auras are common and are phenotypically similar to other auras. Based on the observed duration of aura symptoms, the researchers suggest reconsidering the use of the term “prolonged aura."

A study investigating the genetic determinants of fracture risk identified 15 genetic determinants of fracture, which also influenced bone mineral density. Among the clinical risk factors considered, only bone mineral density demonstrated a major causal effect on fracture, while genetic predisposition to lower levels of vitamin D and estimated calcium intake from dairy were not associated with fracture risk, according to the results.

With a focus on social determinants, the September 2018 issue of The American Journal of Managed Care® (AJMC®) yields new insights on the health effects of food insecurity, health literacy, language barriers, and more. Here are 5 findings from the research published in the issue.

This week, the top managed care news included medical groups asking CMS to halt or slow down its plans to cut physician reimbursement for evaluation and management services; the Senate weighs a package of bills to combat the opioid epidemic; new research shows the Affordable Care Act pushed the uninsured rate down to 10%.

José Baselga, MD, the chief medical officer of Memorial Sloan Kettering Cancer Center, resigned after it was reported that he failed to disclose any industry ties in 60% of the nearly 180 papers he had published since 2013; an idea to give a push to the president’s plan to disclose drug prices on television was sunk this week by House Republicans; transgender adolescents attempt suicide at a much higher rate than young people whose gender identity matches the sex on their birth certificates.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

The National Comprehensive Cancer Network (NCCN) released this week new treatment guidelines for patients for 2 uterine cancers, endometrial cancer, the most common gynecologic cancer, and a rare cancer called uterine sarcoma.

Researchers at Baylor College of Medicine have found that preventing a mutated protein from leaving the nucleus and traveling to the cytoplasm of the cell can help inhibit the growth of leukemic cells in acute myeloid leukemia.

An early review of the second performance period of the Oncology Care Model (OCM) seems to show improvements over the first period.

Arkansas said that 4353 people lost their Medicaid coverage as a result of not reporting their work, volunteer, or job training activities under new rules that requires them to record hours, and will now lose their health insurance for the remainder of 2018.

Researchers determined the incidence and timing of rare, fatal side effects from immune checkpoint inhibitors, and said the number is still extremely low.

BlueCross BlueShield of Tennessee is the latest insurer to announce it will no longer pay for OxyContin and will instead cover newer abuse-deterrent opioids; a new prototype may upend the way people get vaccinated during an influenza pandemic through patches with microscopic needles; as Hurricane Florence prepares to hit the Carolinas, health officials are trying to protect seniors, who tend to be the most vulnerable and bear the brunt of storms.

The announcement comes with word from FDA touting the effectiveness of its efforts to advance digital health regulatory pathways.

The FDA, warning of an "epidemic," said that it is cracking down on the sale of e-cigarettes to kids in the largest enforcement crackdown to date. It also said it may pull the products or issue criminal penalties to keep the immensely popular vaping devices out of kids’ hands.

Pembrolizumab (Keytruda) earned European approval this week, in combination with platinum-based pemetrexed, for the first-line treatment of metastatic nonsquamous non-small cell lung cancer (NSCLC) in adults whose tumors lack EGFR or ALK mutations.

The lawsuit—filed by the American Hospital Association, America’s Essential Hospitals, the Association of American Medical Colleges, 340B Health, Genesis Healthcare System, Kearny County Hospital, and Rutland Regional Medical Center—is asking a federal court to order HHS to make the final rule effective within 30 days.

As levels of disability increased among patients with multiple sclerosis (MS), cost of illness increased and health-related quality of life decreased.

Researchers from the University of Utah explain that patients with attention-deficit/hyperactivity disorder (ADHD) were more than twice as likely to develop early-onset Parkinson disease or a related basal ganglia and cerebellum disease than peers who do not have ADHD. Among patients with more severe disease who are prescribed stimulant medications to control their ADHD, the risk was 6- to 8-fold higher.

The application is based on results presented in March at the 67th Scientific Session of the American College of Cardiology.