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Serum fatty acid–binding protein 4 levels were increased in patients with heart failure with preserved ejection fraction (HFpEF), associated with cardiac remodeling and dysfunction, and linked to poor outcomes.

This week, the top news in managed care included top health care takeaways from the 2020 general election; a Q&A with Dr William Shrank on connecting Medicare Advantage providers and patients; Managed Care Cast discusses balancing evidence with action amid the COVID-19 pandemic.

A new study suggests a potential new marker that could be used to track response to therapy and disease progression in patients with multiple myeloma.

The researchers of the review discuss the reported impact of novel therapies for spinal muscular atrophy (SMA) and highlight the need for long-term data and monitoring of respiratory outcomes.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

AstraZeneca will begin clinical trials of its coronavirus disease 2019 (COVID-19) vaccine in China; 2 states impose stricter mask mandates; President Donald Trump wins counties with highest infection rates.

Vitamin D used as an adjuvant therapy in children with severe atopic dermatitis may improve clinical outcomes, according to a recent study.

New data show combining glucagon-like peptide-1 receptor agonist (GLP-1 RA) exenatide plus sodium–glucose cotransporter-2 (SGLT2) inhibitor dapagliflozin remains effective after 2 years for type 2 diabetes (T2D) uncontrolled with metformin.

New results from the phase 3 ULTIMATE trial show Novartis’ Cosentyx (secukinumab) demonstrated significant treatment response on synovitis in patients with active psoriatic arthritis (PsA) compared with placebo.

Many patients with acute lymphoblastic leukemia (ALL) who undergo chemotherapy end up back in the hospital within 30 days. A new study points out the reasons and opportunities for prevention.

In collaboration with the American Heart Association, Jazz Pharmaceuticals will provide a wide variety of sleep health educational content, including scientific research, reading materials for both patients and practitioners, and podcasts from experts in the field speaking to the importance of sleep on cardiovascular health.

A recent survey of employers revealed a current a shift in organizations working to adopt lower-cost, value-based health care models.

Central retinal vessel density is associated with diabetic retinopathy severity in eyes without, but not with, predominantly peripheral lesions (PPL) according to a study published in JAMA Ophthalmology.

US reports a record number of new coronavirus disease 2019 (COVID-19) cases; FDA reviewers endorse an Alzheimer disease drug; CDC director calls for asymptomatic testing strategy.

In 2020, there is no item more precious than the N95 respirator mask—a symbol of scarcity due to the systematic failures of coordination, preparation, and policy solutions to respond to the coronavirus disease 2019 pandemic.

Authors from the American Society of Nephrology and Kidney Care Partners discuss the response of the kidney care community to the COVID-19 pandemic.

An analysis of state vaccination rates from the previous flu season suggest that certain communities may face significant challenges in achieving coronavirus disease 2019 (COVID-19) immunity.

Partnering with pharmacists ensures prescription availability for patients with HIV during the coronavirus disease 2019 (COVID-19), noted Milena Murray, PharmD, MSc, BCIDP, AAHIVP, of Midwestern University College of Pharmacy.

Despite concerns about treatment with immunosuppressive agents, coronavirus disease 2019 (COVID-19) infection remains low in patients with rheumatic diseases, according to 2 abstracts presented at the annual meeting of the American College of Rheumatology.

Sarcopenic obesity is a condition in which obesity is accompanied by loss of muscle mass and function; the condition is common among older adults with heart failure with preserved ejection fraction (HFpEF).

Although a winner has yet to be declared in the 2020 presidential race, several ballot measures and state level races yielded results with major implications in the health care field. Below is a list of the most influential health care–related outcomes of the 2020 elections.

A decision was upheld that Johnson & Johnson (J&J) must pay a $2.1-billion fine from a 2018 court decision; 3 major drug distributors face up to $18 billion in opioid-related fines; a new diabetes prevention platform may assist in symptom prevention.

The CGRP story is really based on reverse translation and other observations in humans will be pursued along that same model, said Frank Porreca, PhD, professor of pharmacology and anesthesiology at the University of Arizona and a member of the Department of Collaborative Research at Mayo Clinic in Arizona.

Regeneron’s PD-1 inhibitor Libtayo was accepted for priority FDA review for the treatment of first-line locally advanced or metastatic non–small cell lung cancer (NSCLC) with PD-L1 expression of at least 50%.

Older Americans with vision impairment may be less likely to use cancer-related preventive services compared with their counterparts without vision impairment.

There did not appear to be any particular patient characteristics linked with best responses to carfilzomib in patients with multiple myeloma, with the exception of low serum lactate dehydrogenase.

Researchers discuss the development and potential of stem cell–based therapies in the treatment of Parkinson disease.

Variability in prevalence of vestibular migraine, depending on ethnicity and geographic location suggests, a combined genetic and environmental contribution to VM, according to results of a systematic review.

Patients with mild cases of coronavirus disease 2019 (COVID-19) had cellular immunity after 6 months; political support among caregivers of patients with COVID-19 was spotlighted; 2 lots of type 2 diabetes (T2D) drug metformin recalled over possible contamination.

Immune-associated neurotoxicity in patients following chimeric antigen receptor (CAR) T-cell therapy may be due to monocyte-like cells in infusion products, explained Michael R. Green, PhD, University of Texas MD Anderson Cancer Center.