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The mortality risk differs for the 3 endothelin receptor antagonists approved to treat pulmonary arterial hypertension (PAH) in elderly patients; however, a direct comparison in a controlled trial is still needed to confirm results.

In addition to different dosage forms of levodopa—the current standard of care for Parkinson disease—emerging trials are also examining alpha-synuclein, an abnormal protein that may be involved in the pathogenesis of the condition.

A new analysis of CREDENCE data showed that the sodium-glucose cotransporter 2 (SGLT2) inhibitor worked in advanced disease and without causing acute kidney injury.

Patients younger than 65 years represent close to 40% of deaths from metastatic breast cancer, yet their use of end-of-life (EOL) care has not been thoroughly investigated until now.

Drawing on data from 6 randomized controlled trials accounting for over 2200 patients, the researchers the researchers compared the efficacy and safety of olaparib, rucaparib, and niraparib.

The authors of a Commentary in the November 2020 issue of The American Journal of Managed Care describe the experience of reimagining how a home health program can deliver care amid the coronavirus disease 2019 pandemic.

AstraZeneca data show the company's coronavirus disease 2019 vaccine had promising results in older adults; nurses implore the public to take virus safety precautions; a new report highlights employees on food stamps, Medicaid.

At its annual meeting, the American College of Rheumatology previewed updates to guidelines for the management of rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA).

The treatment combination demonstrated an overall response rate of 44% and median overall survival of 9.5 months.

Women filling a prescription for female hormone therapy (FHT), and presumably taking FHT, are not at increased risk of retinal artery or retinal vein occlusions.

Following 6 injections of nusinersen, respiratory muscle performance was significantly better among the treated patients compared with age‐matched historical controls.

Results from a phase 3 study of Xywav in adult patients with idiopathic hypersomnia exhibited its potential to address this unmet medical need.

Severe pulmonary arterial hypertension (PAH) was associated with a significantly higher rate of maternal and fetal mortality.

While patients with severe chronic obstructive pulmonary disease (COPD) are receiving referrals for pulmonary rehabilitation (PR), female patients and other groups are less likely to receive them.

A poster on telehealth presented at ID Week in October attempted to identify where care advancement and improvement are needed for individuals living with HIV.

Final data released overnight show Pfizer’s coronavirus disease 2019 (COVID-19) vaccine is 95% effective; the first at-home COVID-19 test receives a regulatory go-ahead; Amazon launches its first digital drugstore.

For individuals currently in high-risk glycemic categories, losing 2 to 3 kg (4.5-6.5 lb) in combination with increased physical activity over 2 years nearly halved the risk of developing type 2 diabetes (T2D).

While migraine was more manifest in some patients during the pandemic, others were able to adopt healthier habits, said Peter McAllister, MD, a neurologist, board certified headache specialist, and medical director of the New England Institute for Neurology and Headache.

The risk of leukemia is higher for people living near petroleum industry complexes, according to a new analysis of 13 studies of the issue.

Dr. Anthony Fauci discusses the cardiovascular implications of coronavirus disease 2019 (COVID-19) at the American Heart Association Scientific Sessions.

Representation of minority populations in the oncology workforce is important to educate physicians on the meaning of being culturally appropriate, and to provide culturally appropriate care.

The genetic determinants of sleep and migraine partly overlap, suggesting sleep disturbances may causally influence migraine etiology and could be targets for migraine treatment, according to results of a Mendelian randomization study.

The FDA will move rapidly to clear Pfizer's and Moderna’s coronavirus disease 2019 vaccines for emergency use; approval of Alkermes' ALKS 3831 is pending; California's governor is tightening restrictions for 94% of the state’s residents.

Expansion of insurance coverage due to the Affordable Care Act led to a reduction in the use of emergency services for patients with asthma in New York City.

Supplemental screening for breast cancer, beyond the standard-of-care mammography, may benefit some women who have dense breast tissue.

Artificial intelligence (AI) frees up time for clinicians, noted Anthony L. Loschner, MD, assistant professor and associate program director, Critical Care Fellowship Program, Virginia Tech Carilion School of Medicine.

Finerenone may represent an important step forward to reducing cardiac illness and death in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D), the study said.

A machine learning approach that works to identify mitochondrial impairments, a potential mechanism underlying the pathogenesis of Parkinson disease (PD), accurately distinguished between patients with PD and healthy controls.

Half of patients with type 2 diabetes (T2D) exhibit very high cardiovascular risk while the majority are at a high risk of fatal heart attack or stroke, according to new research published in the European Journal of Preventive Cardiology.

An abnormal red reflex finding most likely reflects an underlying ocular pathology in infants, but finding a normal red reflex during screening does not altogether exclude ocular disease.