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The coronavirus disease 2019 (COVID-19) pandemic is the biggest health care story of all time, but that doesn’t mean 2020 didn’t bring other medical and science news. Here are the most-read news articles on AJMC.com for the year on topics other than COVID-19.

A report published by the Personalized Medicine Coalition (PMC) shows that the number of personalized medicines on the market is growing at the highest rate ever recorded by the organization.

The researchers said their results have potential implications for pain management and wellness in older adults, and they suggest that pain catastrophizing could be an important therapeutic target for interventions and pain treatment.

Congress passes legislation that will delay the start of the Radiation Oncology (RO) Advanced Payment Model; examining the newly identified variant of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19); a study finds Hispanics and those without college degrees most subject to excess death during pandemic.

The identification and assessment of frailty, defined as a state of increased vulnerability to adverse health outcomes resulting from loss of physiological reserve, should become a routine aspect of diabetes care, authors of a systematic review and meta-analysis published in The Lancet Health Longevity argued.

The top 5 most-read stories on chronic obstructive pulmonary disease (COPD) of 2020 on AJMC.com focused mainly on ways in which health care treatments for patients can be improved.

In a new review, researchers outline both the underlying pathological mechanisms and potential therapeutic targets in pulmonary arterial hypertension (PAH).

When it comes to the next steps for anti-CGRP therapies, we need to discuss the concept of synergism, said Stephen Silberstein, MD, professor of neurology at Thomas Jefferson University and director of the Headache Center at Jefferson Health.

The American College of Cardiology provides new guidance on the best therapy to prevent blood clots for patients with atherosclerotic cardiovascular disease who also have atrial fibrillation or venous thromboembolism and require an anticoagulant.

A look at some of our most-read news coverage of the coronavirus disease 2019 (COVID-19) pandemic.

Hoping to improve outcomes among patients with acute heart failure discharged from the emergency department, study findings show that 30-day improvements from a self-care intervention were not sustainable through 90 days.

Patients with Parkinson disease were shown to be at greater risk of suicide than matched participants in the general population, according to study findings published last week.

Researchers explored the risk of cardiovascular disease (CVD) as it relates to factors like excess weight, disease evolution time, and clinical activity.

An advisory panel recommends who should receive the next doses of a coronavirus disease 2019 vaccine; bipartisan legislation includes measures to curb surprise medical billing; Tennessee faces virus surge.

The most significant ocular symptom experienced by those suffering from coronavirus disease 2019 (COVID-19) was sore eyes, according to new research published in BMJ Open Ophthalmology.

Results presented earlier this month at ASH showed a 97% overall response rate, and progression-free survival had not been reached.

Four of our top 5 HIV articles for 2020 saw the HIV pandemic overlap with the coronavirus disease 2019 pandemic and had Anthony Fauci, MD, in common. The fifth is from this year's AIDS 2020 virtual conference, itself a product of the overlapping pandemics.

These top 5 posts from our breast cancer compendium in 2020 show that while much is known about breast cancer, much remains that can help to broaden the knowledge armamentarium.

The use of Mohs micrographic surgery, which had the highest average Medicare payment from 2012-2017 among a set of 4 skin cancer procedures, has increased by more than 20%.

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.

The finding about mindfulness-based stress reduction (MBSR) was a secondary outcome of the double-blinded, randomized, placebo-controlled clinical trial. The primary outcome—a reduction in the frequency of migraines—was not reached.

As a neurodegenerative disease, secondary progressive multiple sclerosis (SPMS) may lead to a degradation of cognition skills as the disease progresses.

Researchers review pulmonary function testing measures that span 4 categories that can assess the respiratory muscle dysfunction that happens in diseases like spinal muscular atrophy (SMA).

Researchers found abnormal coherence patterns in survivors of childhood polio.

Amid the coronavirus disease 2019 pandemic, patients with Parkinson disease reporting feelings of loneliness were found to experience greater severity of symptoms.

The analysis reviewed the safety and efficacy among patients in Japan to confirm the findings of the overall study population.

Their work may help to further understanding of the molecular mechanisms of hypomethylating agents (HMAs) and offer a guide for determining which patients are likely to respond to such treatment.

Giving patients icosapent ethyl, or Vascepa, led to a 52% reduction of the total patient-reported symptom outcome prevalence score as compared with a 24% decline for outpatients who received usual care.

Bringing together genetic work with social determinants of health can improve understanding of factors associated with ESKD disparities, said Adriana Hung, MD, MPH, associate professor of medicine at Vanderbilt University, and Bryce Rowan, a statistical genetic analyst.

The FDA Friday issued the second Emergency Use Authorization (EUA) for a coronavirus disease 2019 (COVID-19) vaccine, this one to Moderna, as the pandemic reached critical stress points across the country, especially in California.