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Millions of Johnson & Johnson vaccines spoiled at a Baltimore production plant; CDC adds type 1 diabetes as a comorbidity increasing risk of severe COVID-19; study finds high rates of organ failure among patients with COVID-19 discharged from hospitals.

A review found that a low-carbohydrate diet may lead patients with type 2 diabetes to experience disease remission, potentially providing new insight into how clinicians can help patients better manage their disease, investigators concluded.

Disease severity was strongly associated with health-related quality of life, moderately associated with use of disability insurance, and weakly associated with household income for patients with sickle cell disease.

Among patients with multiple sclerosis, there is a 16% greater risk of infection, including for lower respiratory and herpes virus infections, after administration of fingolimod.

The number of days with sleep disturbance issues, such as difficulty falling and staying asleep, were greater in 2020 than in 2018, as was prevalence of both shorter and longer-than-recommended sleep durations during the pandemic.

Exercise may reduce vulnerability to cognitive decline among at-risk patients with Parkinson disease who have the gene variant APOE ε4.

A survey in France found that systemic medications are used by only half of dermatologists in treating atopic dermatitis, with methotrexate used more than cyclosporine.

Researchers found that physicians may have a financial conflict of interest when examining a chest x-ray for black lung disease, suggesting that sweeping changes are needed to avoid biases and improve transparency.

Using a support vector machine model, researchers were able to distinguish between eyes with pathologic myopia and healthy myopia.

Pfizer/BioNTech’s COVID-19 vaccine appears to be 100% effective at preventing adolescent infections; Vyxeos approved for pediatric secondary acute myeloid leukemia (AML); study results show a 62% drop in pediatric respiratory illness over the past year.

Morbidity and mortality in individuals younger than 55 years with heart failure may be attenuated by targeting possible age-dependent risk factors

FH Healthcare Indicators reveal trends and patterns in the places where patients receive health care.

Nicola Hanania, MD, MS, discusses the future of research on triple therapy and chronic obstructive pulmonary disease (COPD).

Bo Gamble, Director of Strategic Practice Initiatives, Community Oncology Alliance, highlights his questions for the keynote speakers of the 2021 Community Oncology Conference, and takeaways he hopes audience members gain from the sessions.

A cross-sectional study explores the relationship between magnesium, calcium dietary intake, and migraine among men and women.

Researchers developed regression formulas that may be clinically beneficial for estimating visual prognosis after astigmatic correction and determining the surgical indication of astigmatic correction.

This feature is the first in a 6-part series on individuals and international organizations working to bring local and global awareness to the ongoing HIV/AIDS epidemic, which is marking its 40th anniversary this year.

Exposure to indoor formaldehyde can exacerbate atopic dermatitis (AD) symptoms in children with moderate to severe disease, especially in spring and summer and even at allowable levels.

Two therapeutic regimens used for the treatment of chronic obstructive pulmonary disease (COPD) are rarely being prescribed to patients without a COPD diagnosis, investigators concluded.

The Pfizer and Moderna COVID-19 vaccines were shown to be 90% effective in preventing infection in a real-world setting; Biden administration urges states to pause reopening plans amid signs of COVID-19 surge; a lawsuit seeks to end the requirement that preventive services be provided free of charge to Americans.

With most current therapies for patients with multiple sclerosis (MS) targeting disease progression, a recent review evaluated transcranial direct current stimulation’s ability to improve certain disease symptoms.

Medicare Advantage plans have a clear opportunity to improve quality by delivering more comprehensive, timely medication reconciliation services to recently discharged members.

Antibody-based treatments designed to target alpha synuclein and amyloid beta, protein clusters associated with the development of Parkinson disease and Alzheimer disease, were shown to worsen inflammation in the brain.

Johnson & Johnson is reportedly on track to meet its vaccine distribution goal; FDA grants emergency use authorization to Amazon for an at-home COVID-19 test; 6 states expand vaccine eligibility to all adults, with 3 more states to follow later this week.

Anita Makkenchery, MD, MPH, and Brandy Farrar, PhD, discuss the potential for community health workers to become a regular part of the health care system in a post-COVID-19 world.

Investing further in the development of health care staff in often overlooked aspects, such as digital technology and business acumen, can lead to incremental differences in engagement and productivity.

Ted Okon, MBA, executive director, Community Oncology Alliance (COA), speaks on the most significant challenges members encountered in the past year managing the COVID-19 pandemic ahead of the 2021 Community Oncology Conference.

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.

Although the FDA has approved 599 orphan drugs since 1983, patent laws and other exclusivities keep most from any competition.

An ongoing multicenter study in Japan will evaluate reductions in pulmonary vascular resistance 8 months after initiating the combination therapy in pulmonary arterial hypertension.