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United States to buy and donate 500 million COVID-19 vaccine doses to the world; an FDA advisor resigns over a controversial Alzheimer drug approval; Nevada becomes the second state to offer state-managed health insurance plans.

Treatable traits associated with the decline in lung function and quality of life (QOL) in patients with chronic obstructive pulmonary disease (COPD) were detected in a longitudinal study, highlighting targets that physicians can address to better individualize COPD management.

Understanding why this difference exists could assist with finding new therapies, said the authors.

Larry D. Anderson Jr, MD, PhD, associate professor, Harold C. Simmons Comprehensive Cancer Center, discusses updated findings of the phase II KarMMa trial assessing ide-cel chimeric antigen receptor (CAR) T-cell therapy for treatment of adult patients with relapsed or refractory multiple myeloma after 4 or more prior lines of therapy.

Older patients with chronic kidney disease face higher risks of intensive care unit admission and in-hospital mortality if they contract COVID-19, a new report shows.

The UK analysis came from a larger study that examined the effects of a liquid total diet replacement program to induce remission in type 2 diabetes (T2D).

Survey results illustrate the detrimental effects of migraine on daily life.

Compared with their peers receiving injectable treatments for their relapsing-remitting multiple sclerosis (RRMS), children who received newer disease-modifying therapies (DMTs) had improved scores on several measures of disease progression.

Individuals with insomnia had 1.41 times the risk of developing hypertension, compared with people without the sleep disorder.

Results of a systematic review underscore implications of increased rates of metabolic syndrome among youth with type 1 diabetes.

Patients with atopic dermatitis (AD) benefit from extensive patient education. A new report suggests group-based sessions are preferred to individual educational sessions or fun activities.

An initiative launched with the intent to deliver equitable cancer care improved the enrollment rates of Black participants in cancer clinical trials by focusing on community outreach and engagement.

Rebecca Spencer, PhD, professor, Department of Psychological and Brain Sciences, University of Massachusetts Amherst, and co-chair of SLEEP 2021, highlights takeaways from this year’s meeting and discussions she’s looking forward to.

People-first language should be a cultural norm, with patients’ best interests always coming first, and we must encourage everyone to become change agents, according to Milena Murray, PharmD, MSc, BCIDP, AAHIVP, Midwestern University College of Pharmacy.

A study out of Israel shows Pfizer’s COVID-19 vaccine is highly effective in patients with cancer; women with alcohol disorders face adverse health consequences sooner; hundreds of thousands of doses of Johnson & Johnson’s COVID-19 vaccine may expire in June.

Michael Thompson, president and CEO of the National Alliance of Healthcare Purchaser Coalitions, discussed findings of his organization’s Pulse of the Purchaser survey that signaled a return to a stabilized business environment.

Deep brain stimulation of the subthalamic nucleus was shown to remain effective in treating motor complications of people with Parkinson disease 15 years after initial surgery.

Camille Hertzka, vice president and head of oncology, US Medical, AstraZeneca, speaks on how the OlympiA findings may warrant greater need of genetic testing for BRCA mutation and the efficacy of olaparib by patient subgroup.

Progressive rehabilitation produced superior results among patients randomized to a 36-session program during or following hospitalization for acute decompensated heart failure vs those randomized to usual care.

With 5 chimeric antigen receptor (CAR) T-cell therapies approved by the FDA, and 299 agents in the pipeline, it’s no surprise that the virtual meeting of the European Hematology Association (EHA) will have a heavy presence of CAR T research being presented in sessions and posters.

FDA and ASPR issue policy recommendations to reform US pharmaceutical supply chains; insurer coverage implications of the newly approved therapy in Alzheimer disease; Apple announces new health data sharing features.

A study examining how US biosimilar uptake has evolved found that biosimilars launched more recently have seen better uptake than biosimilars that have been on the market for a longer period.

The researchers created a model that simulated what would happen when health systems and providers began working together in Medicare accountable care organizations (ACOs) in arrangements that did not extend to outright mergers or acquisitions.

Rajat Bannerji, MD, PhD, Chief, Section of Hematologic Malignancies at Rutgers Cancer Institute of New Jersey/RWJBarnabas Health, speaks on the efficacy and safety findings of the CAPTIVATE study examining the fixed-duration regimen of ibutinib and venetoclax combination therapy in CLL.

Results of a nationwide study show earlier onset of type 1 diabetes (T1D) is associated with worse glycemic outcomes and presence of albuminuria.

Adherence to antiretroviral therapy (ART) can be improved by health care providers reinforcing ART dispensing models and creating ART models that promote situational stability, according to a new study.

Almost half of US migraineurs hesitate to seek out care for their condition, according to research presented at the American Headache Society's 63rd Annual Scientific Meeting.

The FDA approves a new drug for Alzheimer disease; COVID-19–related hospitalization rates are on the rise among adolescents; efforts to address racism, discrimination, and implicit bias in health care; the United States will send 1 million Johnson & Johnson COVID-19 vaccines to Mexico cities along the border and resorts.

Shalini Paruthi, MD, medical codirector, St. Luke’s Hospital Sleep Medicine and Research Center, and cochair of SLEEP 2021, discusses the sessions and discussions she is looking forward to at this year's meeting.