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A trastuzumab biosimilar was found to have similar safety and efficacy with the reference product (Herceptin) in patients with advanced gastric cancer, a population previously excluded from bioequivalence studies for trastuzumab biosimilars.

Chelsee Jensen, PharmD, pharmaceutical formulary manager at the Mayo Clinic, provides her take on why practices will have to continue to stock multiple biosimilars for the same reference product.

A retrospective study found that chronic obstructive pulmonary disease (COPD) was associated with postoperative pulmonary complications and longer length of stay (LOS) following lung cancer resection.

Without addressing rising costs, the problem of underinsurance in health care coverage will remain, said panelists at the 2022 V-BID Summit, discussing some of the smaller steps that are being proposed or are already in place to try to ease the financial burden.

Young adult men with chronic rhinosinusitis with nasal polyps were shown to be at greater risk of nasal polyp recurrence after endoscopic sinus surgery than elderly men and adult women of all ages.

Analyses of blood-based markers showed an association between diabetes and higher glycated hemoglobin with cognitive impairment among those with Parkinson disease.

Compared with other racial/ethnic groups, Black patients with type 1 diabetes (T1D) presented to medical centers with diabetic ketoacidosis (DKA) more often throughout the COVID-19 pandemic, regardless of COVID-19 infection.

Stephen Rozzo, PhD, associate vice president and head, Biologics Medical Affairs, Sun Pharma, North America, explains tildrakizumab’s mechanisms of action in the treatment of psoriasis and how the drug differs from other approved biologics.

At the 2022 V-BID Summit, hosted by the Center for Value-Based Insurance Design at the University of Michigan, representatives of CMS and the Commonwealth Fund gave an update on the efforts to monitor, evaluate, and improve health equity in the United States.

A panel of experts advised the FDA to support the development of COVID-19 variant-specific booster doses; the CDC is undergoing a month-long review in efforts to revamp the agency; the Environmental Protections Agency (EPA) proposed a rule to ban asbestos.

The authors found that the relationship between immunosuppressive cells and effector T cells in hilar and distal cholangiocarcinoma has important implications for treatment, in that the tumor microenvironment would likely need to be primed for a treatment strategy to be effective.

A large systematic review on pregnant women living with HIV found that protease inhibitor–based antiretroviral therapy (ART) use was associated with increased risk of babies being born small or very small for their gestational age, but not with other adverse pregnancy outcomes.

A recent study found a correlation in patients with an IgE-mediated food allergy (IgE-FA) reporting symptoms of eosinophilic esophagitis (EoE), leading researchers to conclude screening for EoE may be beneficial.

Age at symptom presentation was significantly associated with longer symptom duration for children with juvenile idiopathic arthritis (JIA).

Dennis P. Scanlon, PhD, professor of health policy and administration at Pennsylvania State University and editor-in-chief of The American Journal of Accountable Care®, talks about major systemic and fundamental barriers to health systems becoming learning health systems.

Although the widespread use of low dose computed tomography screening for lung cancer has led to improved mortality in recent years, disparities in uptake persist throughout the United States.

President Joe Biden announced plans to increase research on long COVID-19; the Oklahoma House voted 70-14 in favor of a near-total abortion ban; Walgreens is going to trial in Florida’s opioid epidemic lawsuit.

Marc-Andre Cornier, MD, professor and director of the Division of Endocrinology, Diabetes and Metabolic Diseases at the Medical University of South Carolina, explains recent research on a behavioral weight loss intervention.

Why persons with type 1 diabetes and continuous insulin infusion fail to achieve optimal glycemic control was the subject of a recent focus group analysis conducted among 37 adult men and women.

A recent study found that nocturnal nasal congestion in patients with hypertension and comorbid obstructive sleep apnea (OSA) was associated with uncontrolled blood pressure (BP).

Patients with atopic dermatitis who achieved rapid changes in skin pain severity with the Janus kinase inhibitor baricitinib were associated with clinically significant improvement in Dermatology Life Quality Index scores.

Panic disorders and specific phobias were the mental disorders most often seen among individuals who have chronic thromboembolic pulmonary hypertension (CTEPH), according to new research.

Complications were significantly associated with low height, high-dose prednisolone use, and progression of cervical spine lesions in early disease stages of rheumatoid arthritis (RA).

In this case, a patient died 18 months following his transplant after developing de novo intrahepatic cholangiocarcinoma.

A recent study found that retinal age gap, defined as chronological age subtracted from retinal age, is a potential indicator of Parkinson disease development.

The Biden administration plans to expand Affordable Care Act (ACA) coverage to more families; new guidelines jointly announced by cardiology organizations for the treatment and prevention of heart failure; World Health Organization estimates that 99% of people worldwide are exposed to poor air quality.

A small study conducted in Melbourne, Australia, found that older age and being from a culturally and linguistically diverse community were associated with less awareness of pulmonary rehabilitation among patients with chronic obstructive pulmonary disease (COPD).

Mitigating the high cost of prescription drugs is a win-win to address the complex, multipronged problem of getting patients to take their medications as advised.

Two abstracts presented at the 2022 American Academy of Dermatology (AAD) Annual Meeting explored the health-related quality of life (QOL) and mental health impact of psoriasis disease burden by severity and affected body region.