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The research could pave the way for therapies that target enhancers of disease-related genes.

Using data from the National HIV Surveillance System, the National Center for Health Statistics, and the US Census, a team from the CDC investigated lifetime HIV risk in the United States.

It is not yet clear what impact proactive screening might have on health care costs and survival outcomes.

In this contributor piece, the connection between the complexities of mental health and heart disease in at-risk communities is explored, with the authors stressing the importance of risk factor evaluation and multidisciplinary patient education from both mental and physical health providers.

Findings of a survey of large employers indicate that utilization management tools are ineffective in controlling health care costs for employees and may lead to barriers to treatment.

Reduced health-related quality of life was identified in patients with chronic rhinosinusitis with nasal polyps compared with the general population—regardless of previous sinus surgery or presence of comorbidities.

With responses to current treatments varying among patients with spinal muscular atrophy (SMA), the researchers emphasized the importance of more prognostic markers for improved decision making.

This new study used data on women with stage 0 to II breast cancer to investigate their long-term quality of life (QOL) as it related to choice of surgery and the decision to undergo adjuvant radiation therapy.

COVID-19 and overdoses were 2 main factors in the record high 2021 US death rate; nurse practitioners licensed in New York have been granted full authority to practice independently; the Biden administration announced its goal to improve health care in rural areas.

The researchers found the associated risk was similar to that of obesity on diabetes and greater than that of smoking.

Researchers presented results for ZB131, a monoclonal antibody that would target cancer-specific plectin (CSP); experiments with mice showed this may be present in more than 80% of the most common types of cholangiocarcinoma.

A recent study found that behavioral problems in adolescents with attention deficit/hyperactivity disorder (ADHD) were associated with chronotype, a person’s circadian preference.

Roxana Siles, MD, FAAAAI, staff in the Department of Allergy and Immunology at Cleveland Clinic and codirector of the Asthma Center at Cleveland Clinic, addresses the factors that contribute to necessitating multispecialty management of patients with chronic cough.

The researchers found that the prognostic values for both overall and progression-free survival remained even after adjusting for the International Prognostic Index, a widely used prognostic model of outcomes for the disease.

Camille Hertzka, vice president, head of oncology, US Medical, AstraZeneca, clarifies testing for the HRR mutation in metastatic castrate-resistant prostate cancer (mCRPC) and the predictive importance of radiographic progression-free survival (rPFS) for overall survival in this setting.

Researchers investigated polypharmacy incidence in one of the fastest-aging regions in Spain.

A study conducted in Saudi Arabia found that the severity of dry eye disease (DED) was associated with the amount of quality sleep participants received.

A recent review found that factors influencing blood eosinophil stability, a potential biomarker for chronic obstructive pulmonary disease (COPD), need further research.

Improvements in time spent in target range and glycated hemoglobin A1c were investigated among 34 children with type 1 diabetes (T1D) with a history of daily insulin use and no prior use of diabetes technology.

White House seeks to reduce medical debt of Americans amid rising inflation; Biden administration asks federal appeals court to resume enforcement of a COVID-19 vaccine mandate for federal employees; Philadelphia to reimpose mask mandates in indoor public settings.

In patients with intermediate- to high-risk, use of pegfilgrastim biosimilars could optimize management of FN risk.

Researchers found no association between the use of tofacitinib, tocilizumab, or tumor necrosis factor (TNF) inhibitors and risk of developing Alzheimer disease and related dementia (ADRD) among older patients with rheumatoid arthritis (RA).

Marc-Andre Cornier, MD, professor and director of the Division of Endocrinology, Diabetes and Metabolic Diseases at the Medical University of South Carolina, outlines the necessary components for a successful weight loss program.

Flow–minimal residual disease (MRD) assessment in patients with multiple myeloma (MM) was found to be a good tool for early detection of MRD and could aid providers in treatment decision-making.

Patient-reported treatment goals for psoriasis showed varied preferences according to characteristics such as age, severity, and gender, but the top goal overall was to have confidence in the therapy.

Across 3 disease states, dupilumab has been shown to create rapid, clinically meaningful responses that were sustained, which could improve adherence and the patient-provider relationship.

Black children with systemic lupus erythematosus (SLE) are at the highest risk of adverse renal outcomes, the study found.

On this episode of Managed Care Cast, Perry N. Halkitis, PhD, MS, MPH, dean of the Rutgers School of Public Health, discusses training the next generation of public health professionals.

Findings suggest measuring excess weight in patients may help predict the development of radiation pneumonitis.

Rural hospitals find themselves targets of cyber attacks; a shortage of baby formula follows a nationwide recall; COVID-19 cases likely undercounted.