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The German-Australian AML Study Group, one of the largest global groups evaluating treatments for acute myeloid leukemia (AML), has published results in the New England Journal of Medicine that now classifies AML into 11 classes based on the harbored genetic mutations.

A commentary in the special issue of JAMA on obesity argues that the nation has reached a point where therapy can no longer undo the damage of poor diets and lack of exercise, and a reckoning of policy change is needed.

An additional 3 defendants are joining 6 others previously charged for one of California’s largest healthcare fraud schemes.

Even in a state with relatively few Medicaid restrictions on hepatitis C virus medications, a low number of patients requested treatment.

States are taking the lead in the fight against rising drug prices. Vermont has passed legislation to regulate yearly drug price hikes and other states have introduced similar legislation.

What we're reading, June 8, 2016: obesity rate among women reaches record high; abuse-resistant opioid recommended for approval by advisory panel; and Gilead does not owe Merck money in drug-patent dispute.

The Department of Justice has announced that Genentech and OSI Pharmaceuticals “will pay $67 million to resolve False Claim Act allegations that they made misleading statements about the effectiveness of the drug Tarceva to treat non-small cell lung cancer.”

Mental disorders rank number 1 as the most costly of all health diseases in the United States, with a total estimated spending of $201 billion in 2013.

Many patients 65 years or younger are still receiving aggressive cancer treatment in their final months of life despite Choosing Wisely recommendations encouraging symptom-directed palliative care.

The appellate ruling flatly rejected the request to overturn regulators' approval of Horizon's tiered network. But this is not the end of litigation over the controversial plan.

Can the Oncotype DX Breast Cancer Assay impact recommendation and receipt of chemotherapy in early stage breast cancer? Does the test also improve patient experience? These were some of the questions asked by researchers at the University of Michigan, and the results presented during the annual meeting of the American Society of Clinical Oncology.

Older patients and those with other complications are at greatest risk.

There is a significant variation in quality of urgent healthcare provided during virtual visits, according to a new study published in JAMA Internal Medicine.

What we're reading, June 7, 2016: opioid restrictions disproportionately affect older patients with chronic pain; Genentech and OSI Pharmaceuticals settle Tarceva lawsuit; and trouble raising Zika virus funds.

The American Society of Clinical Oncology’s first-ever clinical trial is growing with the addition of its seventh and eighth pharmaceutical companies, Bayer and Merck, and 30 additional trial participants.

After reading two CDC accounts of this strange set of symptoms among gay men, Anthony S. Fauci, MD, recalls redirecting his research efforts to combat a disease that didn't even have a name.

The first study sheds light on the complex interaction between underlying metabolic risk and breast cancer.

What we're reading, June 6, 2016: Vice President Joe Biden will announce the launch of an open-access cancer research database, and a new bill in Congress would allow companies to repurpose existing drugs for rare diseases.

A secondary analysis of data from the TECOS trial of sitagliptin finds that the drug does not affect the risk for heart failure hospitalization or related adverse clinical outcomes in people with type 2 diabetes

An analysis by Avalere Health of Hillary Clinton’s proposal to allow Americans age 50 and over to Medicare estimates that 13 million adults who are uninsured or have individual coverage through the private market could be eligible for such a program.

The top managed care stories this week included an update to the American Society of Clinical Oncology's value framework, a study that reported readmission rates among safety net hospitals after cancer surgery, and findings that bariatric surgery can benefit patients with diabetes.

Cardiovascular outcomes trials, new technologies, and the fight over what we eat will be featured at the upcoming 76th Scientific Sessions of the American Diabetes Association in New Orleans.

Donald B. Verrilli won key cases to keep intact the Affordable Care Act. With his winning argument in the 2015 case to extend marriage equality to all states, same-sex couples could no longer be denied the right to cover a spouse on an insurance policy or be named next-of-kin for medical decisions.

Recent coverage of our research, in both the healthcare and mainstream press.

A study presented at the ongoing European Obesity Summit has confirmed a correlation between the risk of developing high grade prostate cancer and high body mass index and waist circumference.

What we're reading, June 3, 2016: Florida's crackdown on opioid prescriptions is working; some California physicians are uneasy about prescribing lethal doses to terminally ill patients; and Ashish Jha, MD, MPH, shines a spotlight on the real culprit of preventable medical errors.

The 57-year-old music icon officially became the most high-profile victim of the nation's opioid epidemic.

Interim results from the ongoing CANVAS (Canagliflozin Cardiovascular Assessment Study) clinical trial have found an increased risk of leg and foot amputations associated with the popular diabetes medication.

People who live in the country’s 2 biggest states that have not expanded Medicaid have more complaints about healthcare costs and quality and would like their states to expand the program.

Cigna and Anthem, which are potentially merging in the future, both announced they were taking steps to curb inappropriate opioid and prescription drug use.