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Results of the landmark study, the first in a series of renal outcomes studies for SGLT2 inhibitors, will be of great interest to policy makers given the cost of dialysis to Medicare.

For endocrinologists, a cardiologist, a diabetes educator, and a room full of fellow health workers, the cost of doing nothing—not just to treat diabetes, but also to prevent it— is what feeds into the exorbitant cost of the disease, according to presentations and a panel at the inaugural meeting of the Institute for Value Based Medicine (IVBM) in Diabetes, an initiative of The American Journal of Managed Care®.

Prevalence of depressive symptoms among individuals with HIV may lead to an increased risk of mortality.

A preliminary study discussed how a vaccine regimen stimulated dendritic cells to attack tumors, which could point to a new way of making immunotherapy effective in cancers that have proved resistant to treatment thus far.

During the European Congress of Clinical Microbiology & Infectious Disease (ECCMID), being held in Amsterdam, the Netherlands, April 13-16, researchers are presenting findings that suggests the mode of delivery influences the development of gut microbiota in infants, regardless of a mother’s use of antibiotics, which could then affect infants’ respiratory health during his or her first year.

It's been about a year since the FDA approved the first in a new type of drug to prevent migraines. Here are 5 ways migraines impact patients, from workplace issues to other related health conditions.

Study data revealed that 55% of women over age 70 are at risk of fragility fractures, but 75% of these women are not treated for osteoporosis.

Results from a recent study suggest that a revolutionary treatment may have the potential to slow, stop, or even reverse the progression of Parkinson disease.

The FDA has granted accelerated approval to erdafitinib (Balversa) for the treatment of adult patients with locally advanced or metastatic bladder cancer with fibroblast growth factor receptor (FGFR)3 or FGFR2 mutations who have progressed on platinum-containing chemotherapy.

Approximately 45% of cancer deaths expected in 2019 will be related to modofiable risk factors, such as smoking and alcohol use. However, the prevalence of these risk factors vary by racial/ethnic group, as well as education level.

This week, the top managed care news included CDC clarifying its opioid guidelines for chronic pain; pharmacy benefit managers testifying before a Senate committee; Sanofi expanding its insulin savings program starting in June.

When antibiotics were discovered, they were considered a miracle. Decades of overuse have created a current public health crisis with a growing number of antibiotic-resistant bacteria. However, not all hope is lost in the fight against antibiotic resistance. There are programs in place to promote judicious use of antibiotics and policies and funding to help incentivize development of new antibiotics.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

Women who are screened for cervical cancer are significantly less likely to develop rare types of the cancer, especially among women who had 2 tests.

Human papillomavirus (HPV) infection rates are increasing among women under age 40 who haven't received the HPV vaccination; Ride Aid will stop the sale of e-cigarettes over the next 90 days; the Ohio governor signed a ban on abortion after a detectable heartbeat with no exceptions for pregancies resulting from rape or incest.

A recently published study looked to evaluate the effect of a single dose of nilotinib (Tasigna) in patients with PD. While nilotinib is FDA approved for the treatment of adult patients with chronic myeloid leukemia and not PD, the drug is able to penetrate the blood-brain barrier and reduce inflammation as well as lower levels of a toxic protein that prevents the brain from utilizing dopamine stored in vessels in areas of the brain that may control movement.

Researchers of a recently published study used preclinical behavioral models of migraine to determine that the application of calcitonin gene-related peptide (CGRP) to the dura mater, or the protective outer layer between the skull and the brain, in mice triggers pain responses only in females.

The filing comes as recent upgrades to NCCN guidelines expand the role of testing in the treatment of ovarian cancer.

In a disucssion about closing the rural cancer care gap, 3 themes emerged: local efforts, clinical trial access, and telehealth.

The United States ranks highly in a global study examining traffic-related pollution and new cases of childhood asthma, and the authors suggest that pollution guidelines may need to be re-evaluated, since most affected children live in areas where pollution falls within current limits.

Assessing 4 dose levels of carfilzomib, researchers have determined that the drug, in combination with thalidomide and low-dose dexamethasone, is highly safe and effective in transplant-eligible patients with newly diagnosed multiple myeloma.

The findings represent the first in a new wave of renal outcomes trials in the sodium glucose co-transporter 2 (SGLT2) inhibitor class, a game-changing group of type 2 diabetes drugs with many benefits beyond lowering blood glucose.

A new study has found that prevalence rates of chronic obstructive pulmonary disease varied by occupation.

Senator Bernie Sanders, I-Vermont, has reintroduced a Medicare for All bill while other Democrats eye an alternative; the Trump administration is appealing a federal judge's decision to toss out Medicaid work requirements in Kentucky and Arkansas; AIDS activists are pushing CDC to force Gilead to give the agency royalties for Truvada.

This week, the Institute for Clinical and Economic Review (ICER) released a Draft Evidence Report assessing the clinical effectiveness and value of 2 potential drug therapies to treat individuals with peanut allergy.

A study of gay and bisexual men found that incidence of sexually transmitted infections (STIs) increased following pre-exposure prophylaxis (PrEP) initiation.

Rising consumerism, new competition, and payment models designed to keep patients out of acute care are forcing hospital-centric enterprises to rethink their delivery models. Organizations that excel in building integrated care delivery ecosystems and lasting consumer relationships based on a differentiated brand promise and superior outcomes will be the ones that find success.

The fourth annual Numerof Survey Report outlined the evolution of population health management in the United States. The report found that while the population health management has been gaining momentum, initiatives toward adopting risk-based models have stalled.

The American College of Physicians has updated their breast cancer screening guidelines to recommend that women of average risk of breast cancer get a mammogram at age 50 and every other year; the FDA advised clinicians against aburptly halting opioid prescribing for patients with chronic pain; New York’s mayor declared a public health emergency over the state’s measles outbreak.

Diabetes is associated with an increased risk of death in patients with chronic obstructive pulmonary disease (COPD), but use of metformin can mitigate and even reverse this risk, according to a new study.