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Relying only on data may fail to account for the effects of smoking.

What we're reading, October 14, 2015: Jeb Bush offers a detailed proposal for his plan to replace parts of the Affordable Care Act, California places a cap on out-of-pocket costs for consumers, and people addicted to opioids can't get the treatment they need.

The American Society of Clinical Oncology has issued a statement asking for an improved evidence base for treating older adults with cancer.

Even though the US spent far more on healthcare in 2013 than other comparable high-income countries, it has the lowest life expectancy and some of the worst health outcomes, according to a study by The Commonwealth Fund.

After 2 years, those drinking red wine had improved "good" cholesterol and other benefits.

A new study, published in JAMA Oncology has identified a widespread gap in counseling services for patients who undergo BRCA testing.

What we're reading on October 13, 2015: presidential hopeful Marco Rubio taps health policy expert Avik Roy to advise his campaign, Democrats will tangle over healthcare in first debate, and the US pays 3 times as much for medicine as Britain.

Although nearly 15 million Americans have obtained health coverage under the ACA, another 15.7 million are eligible but do not have coverage.

A study presented at the European Society of Cardiology meeting has found that cancer increases cardiac stress, which is further accentuated by chemotherapy.

Stand Up 2 Cancer, in collaboration with the American Association for Clinical Research, will be funding innovative research grants with a potential to further translational cancer research.

A new report found that while geographic gaps narrowed, they will likely persist because state policies to not expand Medicaid will mean the poor will continue to turn 65 with health issues having gone unaddressed.

What we're reading on October 12, 2015: health insurance marketplaces may have challenges keeping customers they already have, but in California, consumers leaving the state insurance exchange are gaining coverage elsewhere, and the government is increasingly pursuing cases of potentially unnecessary procedures.

The new test, developed by Dako, will provide information on the survival benefit of patients with non-squamous NSCLC treated with nivolumab.

A close study of one patient-reported outcome has deemed it a clinically valuable measure, according to a study published in the Journal of the American College of Surgeons.

Not only do healthcare markets across the country vary, but there are stark differences between healthcare markets within the same state, according to the Healthy Marketplace Index Report from the Health Care Cost Institute.

Top managed care stories this week include how much waiting to see the doctor costs patients, Express Scripts announced it will cover both PCSK9 inhibitors, and HHS proposed simplifying rules for providers using electronic health record.

Researchers have found a high number of older adults with chronic obstructive pulmonary disease are using opioids excessively even though the drug may negatively effect lung health, according to a new study.

Turing Pharmaceuticals has yet to reduce the price of Daraprim, despite statements that the company would do so following public outcry over the 5000% increase overnight in the drug's cost.

A new study published in JAMA Oncology has identified disparate survival outcomes across sites of care.

The PD-1 inhibitor antibody was approved by the FDA for use in patients who have progressed on platinum-based treatment.

Prescription drug spending rose faster than overall spending by several percentage points from August 2014 to August 2015, well ahead of categories like spending on hospitals and doctors.

With the final guidance expected in November, UK will follow Europe in the use of pembrolizumab in treating advanced melanoma patients refractory to previous treatment as well as those who have not been previously treated.

With Express Scripts' coverage starting Monday, here's some background on Praluent and Repatha.

Nearly 70 people have been recommended to receive testing for hepatitis B and C and HIV after they received flu shots from syringes that had been reused.

A new study published in the journal BMJ Innovations that surveyed doctors and nurses in the United Kingdom has found routine breach of patient privacy through the use of digital devices.

Many individuals with chronic obstructive pulmonary disease (COPD) are only diagnosed after they experience late-stage exacerbations, but a new tool could hasten the process of diagnosing cases of COPD.

Steven Rosenberg, MD, chief of surgery at NCI's Center for Cancer Research, has been awarded the 2015 Samuel J. Heyman Service to America Medal, or Sammie for his contributions to the field of immune-based cancer treatments.

Taking aim at payment models for patients on dialysis is the latest attempt to target high-cost areas of Medicare spending.

A retrospective follow-up in women who had received grafts of cryopreserved ovarian tissue discovered a 30% success rate in bearing a child.

Intense lobbying and charges of bias surround the late efforts to influence what goes into the 2015 Dietary Guidelines for Americans. A recommendation from an advisory committee to eat less red and processed meat has fueled most of the controversy.