Heart Failure

The AJMC^® Heart Failure compendium is a comprehensive resource for clinical news and expert insights for the chronic condition in which the heart doesn't pump enough blood due to damaged heart muscle.

Latest News

the top 5 heart failure content of 2024

Top 5 Most-Read Heart Failure Articles of 2024

By Hayden E. Klein

December 23rd 2024

Some of the top heart failure research looked at statins and semaglutide for heart failure with preserved ejection fraction, diabetes-related heart failure risks, and the protective cardiovascular effects of COVID-19 vaccination.

Top 5 conference coverage of 2024

Top 5 Conference Coverage of 2024

By Hayden E. Klein

December 17th 2024

Highlights From ESC Congress 2024

ICYMI: Highlights From ESC Congress 2024

By Hayden E. Klein

December 12th 2024

Tirzepatide box sold as Mounjaro | Image credit: Cynthia – stock.adobe.com

How Tirzepatide Benefits Patients With Obesity-Related HFpEF

By Hayden E. Klein

December 5th 2024

Doctor writing prescription | Image credit: 18percentgrey – stock.adobe.com

SGLT2i Prescriptions for Heart Failure Are Rising, but Vary Across US

By Hayden E. Klein

November 18th 2024

Heart Failure Clinical and Economic Burden

An in-depth discussion on the clinical and economic burden of treatment for patients with heart failure, with special consideration to progressive disease.

John McMurray screenshot

Continuing Medical Education

January 29th 2025

Exploring Transthyretin-Mediated Amyloidosis and Its Phenotypes: A Comprehensive Approach to Patient Treatment

1.5 Credits / Cardiology, Neurology, Rare Diseases

January 29th 2025

The Economics of Transthyretin-Mediated Amyloidosis: Balancing Equity and Access in Resource Allocation

1 Credit / Cardiology, Neurology

January 29th 2025

Evidence-Based Guidelines Point to Leap in Care for Hypertrophic Cardiomyopathy

1.0 Credit / Cardiology

More News

gender differences image depicting the icons for women and men

March 19th 2022

Women Less Likely to Receive Lifesaving Treatment Following Cardiogenic Shock

Laura Joszt, MA

As a result of being less likely than men to receive lifesaving treatment when experiencing cardiogenic shock, women were significantly less likely to survive in the short and long term.

March 14th 2022

Adverse Drug Effects Across Patients With Heart Failure: A Systematic Review

Michael Butzner, MPH Ralph J. Riello III, PharmD Phil Sarocco, RPh, MSc Nihar R. Desai, MD, MPH

This systematic literature review reports incidence of adverse drug effects associated with guideline-directed medical therapy for patients with heart failure with reduced ejection fraction.

Image of mind-heart connection

March 11th 2022

Greater CVD Risk Seen Among Individuals With SMI

This new study investigated cardiovascular disease (CVD) risk outcomes among patients with a serious mental illness (SMI) attending primary care clinics that were part of HealthPartners and Park Nicollet in Minnesota and Wisconsin.

Image of a heart alert

March 8th 2022

Worsened Heart Failure Mortality Seen in Presence of Hyperlactatemia

A new study of patients receiving care for acute heart failure at Rambam Health Care Campus in Haifa, Israel, investigated how their clinical outcomes might be affected by elevated lactate levels and primary acid-base disorders.

Image of a heart

March 4th 2022

Inadequate Testing for CAD Infuses Heart Failure Space

This new analysis of commercial and Medicare Advantage claims from all 50 states investigated utilization of and testing trends for coronary artery disease (CAD) among adults aged 18 and older presenting with new-onset heart failure.

Image of African American Couple

March 1st 2022

Measures of Resistant Hypertension Linked to Worse Outcomes Among Black Adults

A new study has investigated the influence of xanthine oxidase activity and mitochondrial DNA damage–associated molecular patterns on heart failure and cardiac remodeling among Black adults with resistant hypertension.

Image of a puzzled brain

February 26th 2022

Study Finds Cognitive Frailty May Predict Worsened Heart Failure Outcomes

A new study from Japan has investigated possible associations between cognitive frailty and overall prognosis among elderly individuals who have heart failure.

Image of group of investigators

February 22nd 2022

Further Study Needed to Better Understand HFpEF, Normal NT-proBNP Relationship

This new study investigated the relationship between cardiac function and hemodynamics among individuals presenting with heart failure with preserved ejection fraction (HFpEF) and normal levels of N-terminal prohormone B-type natriuretic peptide (NT-proBNP).

Image of healthy living

February 19th 2022

Overall Heart-Healthy Lifestyle Needed to Ward Off Heart Failure

This new subanalysis of data from the Rotterdam Study investigated life expectancy among women and men who live a healthy lifestyle and do or do not have heart failure.

Image of an older Black male

February 16th 2022

Black Race and Male Gender Associated With Worse HF Risks, Rates

This new investigation, a subanalysis of participant data from the Atherosclerosis Risk in Communities study, examined race- and gender-based differences of heart failure (HF) risk at an older age.

Image of heart ventricles

February 12th 2022

Midwall Striae Fibrosis Is Reliable Predictor of HF Admission

This new study from investigators at University of Calgary investigated the potential of midwall striae fibrosis to predict hospital admission for heart failure.

Image of data investigation

February 10th 2022

Longer-Term Elevated Cardiovascular Risks Evident From COVID-19 Infection

This new analysis of more than 11 million veterans investigated risks of several cardiovascular diseases beyond the first 30 days after COVID-19 infection.

Computer generated image of a heart

February 5th 2022

Heart Failure History May Indicate Greater Risks of Cancer, Related Mortality

This study from Italy investigated potential associations between heart failure and comorbid cancer and whether the existence of heart failure predisposed individuals with both to a higher risk of death.

Image of electronic patient evaluation

February 1st 2022

Overall Effectiveness of Atrial Shunt for HFpEF Remains Questionable

There is a persistent lack of effective treatments for heart failure with preserved ejection fraction (HFpEF), so in this study, investigators examined the impact of an atrial shunt among patients with this disease subtype.

Red and white heart image

January 28th 2022

LV Changes, CABG Contribute to Higher Mortality Risk From Heart Failure

In this new study from China, the link between left ventricular (LV) structural changes and mortality following coronary artery bypass grafting (CABG) was investigated among a patient cohort with heart failure with reduce ejection fraction.

Image of a heart and stethoscope

January 25th 2022

USPSTF Maintains AFib Screening Recommendation

The US Preventive Services Task Force (USPSTF) had announced an update to its 2018 recommendation on screening for atrial fibrillation (AFib) for older adults.

Image of fast walkers

January 20th 2022

Fast Walking Pace Shown to Benefit Patients With Heart Failure

These new study findings support a link between faster walking pace and reduced risk of developing heart failure and its subtypes.

Image of cardiologist holding a heart

January 19th 2022

Timely Cardiac Function Recovery Seen Among Children With COVID-19, MIS

This new short-term matched study from investigators at Children’s Hospital of Philadelphia investigated cardiac-related outcomes among pediatric patients presenting with COVID-19–related multisystem inflammatory syndrome.

Image of a graphic of a broken heart

January 14th 2022

Malnutrition May Decrease Life Expectancy in Those With Heart Failure

The combined effects of obesity and malnutrition among individuals with heart failure were explored in this recent study from France, with the investigators noting that while malnutrition is a risk factor for adverse outcomes, obesity often confers a protective effect.

Image of physician making heart shape with hands.jpg

January 11th 2022

Sodium Restriction May Not Benefit All Patients With Heart Failure

Following a review of trials that evaluated reduced sodium intake among patients with heart failure, investigators found no improvement to patient quality of life or their risks of mortality and hospital readmission.

heart graphic

January 6th 2022

Authors Outline Potential Targeted Therapeutic Intervention for HFpEF

Authors described recent therapeutic developments in heart failure with preserved ejection fraction (HFpEF) and proposed a conceptual framework for more targeted treatment.

diversity graphic

January 3rd 2022

Race and Sex Differences Seen in ICD Use for Hypertrophic Cardiomyopathy

Analysis results revealed racial and sex disparities among patients with hypertrophic cardiomyopathy who receive implantable cardioverter-defibrillator (ICD) devices.

Top 5 most-read heart failure articles of 2021

December 29th 2021

Top 5 Most-Read Articles in Heart Failure for 2021

Laura Joszt, MA

In 2021, there were some changes to recommendations and an important FDA approval for patients with heart failure or who are at risk of heart disease.

Adriaan Voors, MD, University Medical Center Groningen, the Netherlands

December 24th 2021

Dr Adriaan Voors: Health Care Reimbursement May Affect SGLT2 Inhibitor Uptake

Mary Caffrey Maggie L. Shaw

Adriaan Voors, MD, professor of cardiology and director of the Heart Failure Clinic, University Medical Center Groningen, the Netherlands, explains why patients provided sodium-glucose co-transporter 2 (SGLT2) inhibitors in hospitals may be unable to continue the medication after discharge.

Heartbeat

December 19th 2021

Expanded Label of Sacubitril/Valsartan for HF Could Drastically Expand Eligible Population

Laura Joszt, MA

Under the expanded FDA label, up to 1.8 million individuals in the United States could be eligible for sacubitril/valsartan, and up to 180,000 worsening heart failure (HF) events could be prevented or postponed.

Adriaan Voors, MD, University Medical Center Groningen, the Netherlands

December 18th 2021

Dr Adriaan Voors on Possible Unexplained Benefits of SGLT2 Inhibitors

Mary Caffrey Maggie L. Shaw

Adriaan Voors, MD, University Medical Center Groningen, the Netherlands, discusses how and why sodium-glucose co-transporter 2 (SGLT2) inhibitors act so quickly for patients with heart failure.

Stethoscope and heart

December 9th 2021

Investigators Ask if COVID-19 Infection Is to Blame for Cardiac Dysfunction

Findings presented today during EuroEcho 2021 demonstrate a potential link between persistent dyspnea following recovery from COVID-19 infection and subclinical cardiac dysfunction.

Hands gently holding heart

December 7th 2021

Novel Heart Failure Rehab Intervention May Hold Economic Value in the Longer Term

A secondary analysis of economic outcomes–related data from the Rehabilitation Therapy in Older Acute Heart Failure Patients trial attempted to answer if a novel 12-week rehabilitation intervention held cost-effective value.

December 3rd 2021

Variation in Early Diffusion of Sacubitril/Valsartan and Implications for Understanding Novel Drug Diffusion

Lauren Gilstrap, MD, MPH Ashleigh King, MPH Stephanie Tomlin, MS, MPA Andrea M. Austin, PhD

Rates of sacubitril/valsartan diffusion have been slow and there has been significant geographic variation, highlighting the importance of local prescribing patterns in early drug diffusion.

Adriaan Voors, MD,University Medical Center Groningen, the Netherlands

December 2nd 2021

Dr Adriaan Voors Explains Potential Decongestive Benefits of Empagliflozin

Mary Caffrey Maggie L. Shaw

Adriaan Voors, MD, discusses possible mechanisms of action of empagliflozin that produce such beneficial results among patients with heart failure, in an interview about the EMPULSE trial prior to this year’s American Heart Association Scientific Sessions.

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