Bone Health

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Challenges of Fracture Risk Assessment in Asian and Black Women

Challenges of Fracture Risk Assessment in Asian and Black Women

By Joan C. Lo, MD
Malini Chandra, MS, MBA

March 7th 2024

Differences in bone density and FRAX fracture risk scores among Black and Asian women yield greater discordance in fracture risk estimation compared with White women.

FDA approval stamp in red | Image credit: chrisdorney - stock.adobe.com

FDA Approves First 2 Denosumab Biosimilars

By Laura Joszt, MA

March 5th 2024

Standardized Total Knee Arthroplasty Pathway Improves Outcomes in Minority Patients

By Dietrich W. Riepen, MD
Daniel Gelvez, BA

May 5th 2021

Variation in Fracture Risk Estimation Among East Asian Women

By Joan C. Lo, MD
Shefali Nath, MD, MPH

March 10th 2021

Economic Burden of Osteoporotic Fractures: The Tip of the Iceberg?

By Hatice Bolek, MD
Ertugrul Cagri Bolek, MD, MSc

December 11th 2020

More News

Study Evaluates Bone Health in Children With Acute Lymphoblastic Leukemia

July 10th 2018

Study Evaluates Bone Health in Children With Acute Lymphoblastic Leukemia

Alison Rodriguez

Acute lymphoblastic leukemia is the most common type of childhood cancer, and fractures from osteoporosis are an important cause of morbidity in patients with ALL. A recent study aimed to document the annual incidence and predictors of fractures in order to determine whether they occur years after chemotherapy.

Explosive Jumping Can Help Prevent Falls in Women With Osteoporosis Risk

July 7th 2018

Explosive Jumping Can Help Prevent Falls in Women With Osteoporosis Risk

Allison Inserro

Can older women with low bone mass decrease their risk of falls with a fitness trend called explosive jumping? One study says it’s possible, and that it may be worthwhile to incorporate muscle power training into traditional fall-prevention programs.

Female Teen Drinking Before Reaching Peak Bone Mass May Increase Osteoporosis Risk

July 5th 2018

Female Teen Drinking Before Reaching Peak Bone Mass May Increase Osteoporosis Risk

Alison Rodriguez

A recent study found an association between heavy drinking by adolescent females and poorer bone mass later on.

June 29th 2018

Study Summary: DECIDE

Brown JP, Prince RL, Deal C, et al. Comparison of the effect of denosumab, alendronate on BMD and biochemical markers of bone turnover in postmenopausal women with low bone mass: a randomized, blinded, phase 3 trial. J Bone Miner Res. 2009, 24(1):153-161. doi: 10.1359/jbmr.080901.

USPSTF Updates Screening Recommendations for Osteoporosis

June 26th 2018

USPSTF Updates Screening Recommendations for Osteoporosis

Allison Inserro

The United States Preventive Services Task Force (USPSTF) updated its 2011 recommendation about osteoporosis screening, recommending that women over the age of 65 years continue to get screened and issuing new information about how clinicians should use screening tools to evaluate women younger than 65 years at high risk for developing the bone disease.

Following Patients With Osteoporosis During Bisphosphonate Drug Holidays

June 14th 2018

Following Patients With Osteoporosis During Bisphosphonate Drug Holidays

Allison Inserro

A recent study aimed to determine the clinical and laboratory parameters associated with increased fracture risk in patients on holidays from taking bisphosphonates (BP) for osteoporosis.

Pfenex Reports Good Results of Biosimilar for Osteoporosis

June 12th 2018

Pfenex Reports Good Results of Biosimilar for Osteoporosis

Allison Inserro

Biotechnology firm Pfenex recently reported results from its phase 3 PF708-301 study, which showed comparable overall profiles between its biosimiliar drug candidate PF708 and Eli Lilly’s teriparatide (Forteo) for osteoporosis.

Denosumab Shows Good Results in Glucocorticoid-Induced Osteoporosis

June 11th 2018

Denosumab Shows Good Results in Glucocorticoid-Induced Osteoporosis

Allison Inserro

A study comparing denosumab (Prolia) with risedronate (Actone) found that denosumab could be a useful treatment option for patients newly initiating or continuing glucocorticoids who are at risk of fractures. It is the first study to show that denosumab can increase bone mineral density at both the spine and the hip in patients with glucocorticoid-induced osteoporosis.

Discovery About Rare Bone Disease May Also Hold Clues About Bone Health

April 12th 2018

Discovery About Rare Bone Disease May Also Hold Clues About Bone Health

Allison Inserro

National Institutes of Health researchers have uncovered a genetic basis of a rare bone disease known as melorheostosis and said the discovery could offer potential treatment targets, provide clues about bone development, and lead to insights about fracture healing and osteoporosis.

December 20th 2017

Trends in Bisphosphonate Initiation Within an Integrated Healthcare Delivery System

Rami J. Hosein, MD, MPH Joan C. Lo, MD Bruce Ettinger, MD Bonnie H. Li, MS Fang Niu, MS Rita L. Hui, PharmD, MS Annette L. Adams, PhD, MPH

The authors observed a marked shift toward treatment of higher-risk subsets of younger postmenopausal women (with prior fracture and/or with osteoporosis), and away from women at lower risk.

September 21st 2017

Study Finds Areas of Bone Damage in Seniors With Type 2 Diabetes

Authors of the study say the technology exists to screen seniors with type 2 diabetes and identify those at risk of a fracture.

September 13th 2017

Racial and Ethnic Differences in Hip Fracture Outcomes in Men

Lucy H. Liu, MD, MPH Malini Chandra, MS, MBA Joel R. Gonzalez, MPH, MPP Joan C. Lo, MD

Racial and ethnic differences in hip fracture incidence and mortality outcome were observed within a diverse population of older men, with lower rates of both among Asians.

October 17th 2016

More Research Needed to Understand Link Between Diabetes, Fractures

Researchers say more work is needed to create calculators that predict fracture risk in individual patients with diabetes.

October 11th 2016

Mortality Following Hip Fracture in Chinese, Japanese, and Filipina Women

Minal C. Patel, MD Malini Chandra, MS, MBA Joan C. Lo, MD

One-year mortality following hip fracture in Asian American women is comparable among Chinese, Japanese, and Filipina women, comprising nearly three-fourths of the Asian population examined.

May 17th 2016

Referring Wisely: Orthopedic Referral Guidelines at an Academic Institution

Maria E. Otto, MD Carlin Senter, MD Ralph Gonzales, MD, MSPH Nathaniel Gleason, MD

The authors used the modified Delphi method to develop local orthopedic referral guidelines, enabling detailed decision support and nonâ€”face-to-face consultation at the point of referral.

October 15th 2015

Predicting Incident Bone Fractures in Type 1 Diabetes Patients

The standard test for osteoporosis does not do a good job of predicting fractures in T1D.

May 15th 2014

Protecting Bone Health During Cancer Care

Mary K. Caffrey

NCCN Guidelines Updates

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