Acute Lymphoblastic Leukemia/Acute Myeloid Leukemia

Latest News

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Two Leukemia Stem Cell Subtypes Identified

September 6th 2024

Researchers have discovered 2 leukemia stem cell subtypes with distinct epigenetic and transcriptional signatures.

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Surfaceome Analysis Identifies Potential IO Targets in AML

August 31st 2024

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Researchers Identify Potential IO Targets in AML Through Surfaceome Analysis

August 27th 2024

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AML Treatment Has Shifted Toward More Personalized Approach

August 17th 2024

Maria Amaya, MD, PhD
Real-World Outcomes Not Always Reflected in Clinical Trials: Dr Maria Amaya

August 16th 2024

More News

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February 8th 2024

Research Indicates In Utero Origins of Acute Leukemia in Children

Luke Halpern
Circumstantial and direct evidence, including a review of twin and backtracking studies, demonstrate potential prenatal development of acute childhood leukemias.
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January 31st 2024

In AML, Immunotherapy Shows Promise to Expand Treatment Toolbox

Jared Kaltwasser
Most of the research suggests combination therapies might be the best option for many patients who have acute myeloid leukemia (AML).
AML Acute Myeloid Leukemia | Image Credit: momius-stock.adobe.com
January 29th 2024

ELN Risk Category, MRD Status Predictive of Relapse in Patients With AML

Jared Kaltwasser
The study may help explain why some patients are more prone to relapse following a complete response to induction therapy, as indicated by measurable residual disease (MRD) status and 2017 European LeukemiaNet (ELN) criteria.
Blood cells flowing - Катерина Євтехова - stock.adobe.com
January 27th 2024

Increased Fatigue Associated With Greater Risk of Mortality Among Patients With AML, ALL, MDS

Rose McNulty
The findings suggest patient-reported outcomes—namely fatigue—may be helpful in identifying patients at a higher risk of death and other adverse outcomes but warrant further research.
ASH 2023: Coverage of ALL
January 20th 2024

ASH 2023: Coverage of ALL

Mary Caffrey
Selected coverage of acute lymphoblastic leukemia (ALL) from the 65th American Society of Hematology Annual Meeting and Exposition, December 9-12 2023, San Diego, California.
Findings Suggest Utility of Specialized MRD Testing in Management of FLT3-ITD AML With Quizartinib
January 5th 2024

Findings Suggest Utility of Specialized MRD Testing in Management of FLT3-ITD AML With Quizartinib

Mary Caffrey
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December 22nd 2023

alloHSCT Yields Benefits in R/R AML Regardless of Leukemia Burden

Russ Conroy
Those with chronic graft-versus-host-disease who have received allogeneic hematopoietic stem cell transplant (alloHSCT) may experience enhanced graft-versus-leukemia effects, thus producing a lower relapse rate in acute myeloid leukemia.
Blood cells flowing | Image credit: Катерина Євтехова - stock.adobe.com
December 8th 2023

Health Care Resource Use, Cost Burden Appear Substantial in R/R B-Cell ALL

Russ Conroy
Treatment with blinatumomab or inotuzumab ozogamicin particularly confers higher total costs for patients with relapsed/refractory B-cell acute lymphoblastic leukemia.
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November 3rd 2023

High Disease Burden at Acute Leukemia Diagnosis More Common in Black Children, Study Finds

Rose McNulty
A study evaluating disparities among children with acute leukemia found that Black children are more likely to present with higher disease burden at diagnosis compared with non-Hispanic White children.
High LDH Levels Associated With Worse Survival in Newly Diagnosed AML
October 13th 2023

High LDH Levels Associated With Worse Survival in Newly Diagnosed AML

Russ Conroy
Elevated white blood cell counts also appear to correlate with shorter overall survival in patients receiving standard induction chemotherapy plus cytarabine for acute myeloid leukemia.
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September 8th 2023

AML-Specific Early Mortality Risk Indices May Increase Accuracy of Care Quality Measurements

Rose McNulty
A study found acute myeloid leukemia (AML) salvage therapy was independently associated with early mortality compared with frontline therapy, suggesting that algorithms measuring quality of care should incorporate risk mortality indices that factor in disease characteristics and treatment status.
image of leukemia cell
August 29th 2023

Older Patients With AML Less Likely to Receive Genomic Testing, Study Finds

Pearl Steinzor
A study highlights an unmet need for patients with acute myeloid leukemia (AML) to access and afford genomic testing, especially among an older patient population.
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