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Humanistic and Economic Burden of Hepatocellular Carcinoma: Systematic Literature ReviewWorldwide, more than half a million new cases of hepatocellular carcinoma (HCC) are diagnosed annually. The incidence of HCC in the United States is rising with an estimated 31,000 new cases in 2018. Disease prognosis remains poor, with a 5-year survival rate across all disease stages estimated between 10%-20%, and 3% for those diagnosed with distant disease. Although morbidity is significant, especially among patients with advanced-stage disease, limited information exists on the humanistic and economic burden of HCC.
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Primary Care Appointment Availability and Nonphysician Providers One Year After Medicaid ExpansionAfter Medicaid expansion in Michigan, appointment availability for new Medicaid patients stably increased-this is perhaps attributable to increasing proportions of appointments scheduled with nonphysician providers.
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Provider Differences in Biosimilar Uptake in the Filgrastim MarketThe speed and extent of biosimilar penetration differ across provider types. Provider awareness and incentives are significantly associated with biosimilar uptake.
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Modeling the Economic Value of Cardiometabolic Virtual-First Care ProgramsUsing a microsimulation approach, this study modeled the potential multiyear health and economic benefits of participating in cardiometabolic virtual-first care programs.
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Cancer Care Pathways: Hopes, Facts, and ConcernsCancer pathways can potentially improve patient outcomes and reduce costs. Recent concerns about pathway adoption deserve attention, including excessive administrative burden to clinics.
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Automated Phone and Mail Population Outreach to Promote Colorectal Cancer ScreeningAutomated phone and mail population outreach resulted in an almost 4-fold increase in the rate of screening for colorectal cancer even without an office visit.
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Preventing Patient Absenteeism: Validation of a Predictive Overbooking ModelElectronic health record data can be used to predict patient absenteeism accurately. Predictive overbooking of missed appointments can significantly increase service utilization.
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Impact of Complex Care Management on Spending and Utilization for High-Need, High-Cost Medicaid PatientsComplex care management for high-need, high-cost Medicaid patients significantly reduced total medical expenditures and inpatient utilization in a randomized quality improvement trial.
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Patient Safety Intervention to Reduce Unnecessary Red Blood Cell UtilizationThis study evaluated the impact of a patient safety intervention and national guideline to reduce unnecessary red blood cell transfusions in a large, urban academic medical center.
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Electronic Health Risk Assessment Adoption in an Integrated Healthcare SystemSignificant additional outreach and engagement strategies and incentives are likely required to increase adoption and ongoing use of health risk assessment tools among target populations.
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Adalimumab Persistence for Inflammatory Bowel Disease in Veteran and Insured CohortsVeterans with inflammatory bowel disease taking adalimumab appear to be more likely to remain on the drug 1 year after initiation than patients who are privately insured.
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Comparative Effectiveness and Costs of Insulin Pump Therapy for DiabetesEvaluation of healthcare utilization and costs over 3 years for adults with insulin-requiring diabetes who transition from multiple daily insulin injections to insulin infusion pumps.
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Drug Adherence After Price Changes in a Previously Compliant PopulationThe impact of price changes in drugs, at least among previously adherent patients, was modest in size except for drugs with large price changes.
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Payer—Provider Patient Registry Utilized in a Behavioral Health HomeA payer—provider, patient registry to identify individuals with serious mental illness and chronic physical health conditions for utilization in behavioral health homes is described.
