Two case studies examine the benefits of manufacturers and managed care organizations partnering in pragmatic or practical clinical trials to generate real-world evidence.
Inappropriate prescribing practices of opioids are a major risk factor for mortality among opioid users in the Georgia Medicaid population, although risk is lower in managed Medicaid.
Predictive analytics–driven disease management outperforms standard of care among patients with chronic heart failure.
Children who used an electronic monitoring system had as many emergency department visits and hospitalizations for asthma as children who used a paper diary.
We have insufficient understanding of what influences our prescribing behavior, particularly with respect to pharmaceutical marketing strategies.
Disease management programs for diabetes can improve some processes of care, but they do not improve intermediate outcomes beyond doubt.
This retrospective study evaluated real-world implementation of the updated CDC HIV algorithm in a large US laboratory.
Worldwide, more than half a million new cases of hepatocellular carcinoma (HCC) are diagnosed annually. The incidence of HCC in the United States is rising with an estimated 31,000 new cases in 2018. Disease prognosis remains poor, with a 5-year survival rate across all disease stages estimated between 10%-20%, and 3% for those diagnosed with distant disease. Although morbidity is significant, especially among patients with advanced-stage disease, limited information exists on the humanistic and economic burden of HCC.
This study illustrates that where clinical trials are lacking, network meta-analysis can provide valuable insights into the potential clinical and economic benefits of value-based insurance design.
A population health management approach to identify, track, and intervene with diabetic patients before their blood sugar becomes poorly controlled can improve their overall health.
This paper identified 4 factors associated with implementation success of e-consults in 8 VA medical centers, with implications for implementing similar health IT initiatives elsewhere.
Two standardized rating scales appeared to be valid and reliable for use at admission and possibly follow-up in a child psychiatry system of care.
The authors evaluated a brief assessment tool that accountable care organizations can use to help elementary schools improve student nutrition and increase physical activity.
Higher patient cost-sharing is associated with a lower likelihood of treatment augmentation in patients with depression who are treated with antidepressants.
Breast cancer screening may not improve in early medical home implementation.
Minimally invasive radical prostatectomy was more commonly performed in civilian hospitals compared with military hospitals among TRICARE beneficiaries, with comparable postoperative outcomes.
To set priorities for quality improvement in trauma triage, we compared the cost-effectiveness of current practice with interventions to improve physician adherence to clinical guidelines.
This study tested 3 financial incentives encouraging breast cancer screening (mammograms) among women deemed overdue. None were effective overall; "person-centered" incentives worked in the most recently screened subgroup.