Therapeutic persistence with infliximab was associated with signifi cantly fewer ulcerative colitis patients requiring hospitalization; once hospitalized, patients with therapeutic persistence had significantly decreased inpatient costs.
A letter from the guest editor highlights the significant work that remains for provider organizations to integrate digital advancement as a key strategy in addressing some of the most pressing challenges that are transforming the health care landscape.
Woman-level characteristics such as breast symptoms at mammography are associated with earlier follow-up within an integrated health system with an active breast health plan.
Despite universal access to HER2 testing in Ontario, variability in reporting by region and disease severity presents challenges for program evaluation and quality improvement initiatives.
Comparative effectiveness research and pragmatic clinical trials are valued methods to address the limitations of traditional randomized trials, answer questions of cost-effectiveness or noninferiority, and inform data-driven dialogue and decision making by stakeholders.
A quarter of opioid recipients with commercial insurance had at least 1 indicator of potential misuse by patients or inappropriate prescription practices by providers.
Data from a national survey of Veterans Health Administration specialists indicate that referral templates may improve the appropriateness, clarity, and completeness of primary care–specialty care referrals.
The majority of patients prescribed antipsychotic medications in state Medicaid programs are taking these agents for off-label indications.
This study shows how cardiovascular prevention would be much more efficient if risk were used in treatment decisions, but that currently it plays no role.
Encouraging Value-Based Insurance Designs in State Health Insurance Exchanges
This pooled analysis assesses preferred roles in treatment decision making, actual roles, and preferred versus actual discordance among 6 studies of patients with cancer.
For 2 successive years, the Hackensack Alliance Accountable Care Organization achieved cost savings and maintained quality by using physicians with patient-centered medical homes and nurse care coordinators focused on high-risk patients.
Improving adherence to long-term medication therapy remains a challenge. Health information technology interventions that leverage electronic medical records are promising, low-cost approaches for increasing adherence.
Many patients stop taking medications for chronic conditions, thereby reducing the effectiveness of healthcare. An attempt to screen electronic VA healthcare records to identify patients as they discontinued a medication was not an efficient approach to this problem.
A flexible population-based prescription opioid registry was established for addressing a broad range of critical public health questions relating to prescription opioid use.
This report describes the initial implementation of pharmacist-performed comprehensive medication management as part of an interdisciplinary care team at an accountable care organization’s primary care offices.
The authors observed a marked shift toward treatment of higher-risk subsets of younger postmenopausal women (with prior fracture and/or with osteoporosis), and away from women at lower risk.