Switching Study Reports Equivalence Between Filgrastim, Biosimilar in Breast Cancer
A phase 3, randomized, double-blind registration study in patients with breast cancer receiving neoadjuvant myelosuppressive chemotherapy has found clinical equivalence between filgrastim and its biosimilar after switching studies.
Do We Have Adequate Surveillance in Cancer Survivor Care?
A poster discussion session at the 2017 Annual Meeting of the American Society of Clinical Oncology examined retrospective surveillance data in 3 different cancers: non-small cell lung cancer, head and neck cancer, and colorectal cancer.
Physician, Regulatory, and Payer Perspectives on the Value of Real-World Data
One of the kickoff sessions on the first day of the 2017 American Society of Clinical Oncology Annual Meeting in Chicago, Illinois, was a lively discussion on ensuring that the data used to inform patient care and create healthcare policies holds value.
Patient Selection Vital in Ensuring Improved Response to PD-1, PD-L1 Inhibitors in NSCLC
A late afternoon extended education session on the first day of the 2017 American Society of Clinical Oncology Annual Meeting in Chicago, Illinois, was a discussion on the state-of-the-art uses for immunotherapy in the management of non-small cell lung cancer (NSCLC).
ASCO Study Finds Shift in Diagnosis Stage for Several Cancers Following ACA Implementation
Analysis of data available within a national hospital-based registry showed that the diagnosis of stage I disease increased for female breast cancer, colorectal cancer, and lung cancer following implementation of the Affordable Care Act (ACA).
HPV Vaccination May Lower Prevalence of Oropharyngeal Cancers in Young Adults
According to the study, to be presented at the 2017 American Society of Clinical Oncology Annual Meeting, vaccination resulted in an 88% overall reduction in vaccine-type infections and a 100% reduction among men, in the young adult population.
Physical Activity, Healthy Diet Improve Survival in Colorectal Cancer: Study at ASCO
The findings are the results of a collaborative study conducted at various cancer institutions across the United States, which evaluated the impact of following the 2012 American Cancer Society Nutrition and Physical Activity Guidelines for Cancer Survivors.
Ahead of ASCO, Kite Pharma Announces Priority Review of Its CAR-T Treatment
Based on the results of the phase 2 ZUMA-1 trial in patients with refractory non-Hodgkin lymphoma, Kite Pharma has submitted for, and received, a priority review for its chimeric antigen receptor (CAR)-T cell treatment, axicabtagene ciloleucel.
A First: FDA Approves Pembrolizumab for Tissue-Agnostic Indication
The drug is now indicated for adult and pediatric patients with unresectable or metastatic microsatellite instability-high or mismatch repair deficient solid tumors that lack suitable alternative treatments or that have progressed on treatment.
Study Identifies Racial Disparity in Risk of Interval Colorectal Cancer
A study published in the Annals of Internal Medicine reports that black Medicare enrollees are less likely to receive colonoscopy from more highly-rated physicians, which could increase their risk for interval colorectal cancer.
Multigene Testing Can Inform Predisposition to Inherited Prostate Cancer
Comprehensive genetic testing using multigene testing panels for prostate cancer can arm genetic counselors with the information they need to guide precision therapy, even in men with early stage disease but a strong family history of the disease.
Q&A With Daryl Pritchard, PhD, of the Personalized Medicine Coalition
An interview with Daryl Pritchard, PhD, vice president for Science Policy at the Personalized Medicine Coalition, on the FDA's drug approval process, developments in the personalized medicine field, and reimbursement models that integrate diagnostics.
The Value of Regulatory and Healthcare Policy Changes in Oncology Care
At the The American Journal of Managed Care®'s Spring 2017 Oncology Stakeholders Summit, the discussion touched off-label communication, the evolving clinical trial design, and healthcare reform, all while ensuring care is patient-centered.
Pembrolizumab Plus Chemotherapy Approved for Metastatic Nonsquamous NSCLC
Tumor response rate and progression-free survival were the benchmarks that helped pembrolizumab (Keytruda) gain accelerated approval as first-line treatment for metastatic nonsquamous non-small cell lung cancer (NSCLC), in combination with chemotherapy.
WHO Taps Into Biosimilars for Access to Expensive Cancer Drugs in Poor Nations
The World Health Organization (WHO) has announced a pilot project that will take advantage of expected savings from biosimilar medications, particularly expensive anticancer agents, to make these treatments available for low- and middle-income countries.