New Oncology Clinical Trial Designs: What Works and What Doesn't?
Basket and umbrella studies as well as adaptive enrichment design strategies represent novel approaches to testing targeted therapeutics in oncology, and a session at ASCO's annual meeting discussed the nuts and bolts of these design strategies.
Medicaid Enrollees With Hepatitis C Face Reimbursement Challenges
Heterogeneity in Medicaid coverage of the anti-viral agent sofosbuvir is rampant across the United States, with varying reimbursement criteria and lack of conformation to recommendations by professional infectious disease organizations.
ASCO's Conceptual Value Framework Released: Tool for Shared Decision Making
A framework that primarily considers clinical benefit, toxicity, and cost of new treatments was released today by ASCO. A presscast complementing the release described the framework as a tool for providers to discuss value of new treatments with patients, compared with the standard of care.
Proposed Center Within FDA Could Streamline Approval Process for Lab-Developed Tests
The House Energy and Commerce Committee is drafting language that will help create an in vitro center within the FDA to define risk categories for laboratory-developed tests (LDTs), and set timelines to accelerate the approval process for LDTs.
Value of Patient-Reported Outcomes in Oncology Care
To discuss patient-reported outcomes and their importance in patient-centered care, The American Journal of Managed Care convened a panel of healthcare experts to participate in the Oncology Stakeholders Summit, Spring 2015 Peer Exchange.
Novel Options in Melanoma and Multiple Myeloma
Much-anticipated trial results were presented on the third day of the annual meeting of the American Society of Clinical Oncology, held in Chicago. These included phase 3 results from the CheckMate 067 trial and a phase 2 study with elotuzumab.
Stakeholder Definition of Value in Cancer: Where Are We 1 Year on?
While the clinical data presented at the annual meeting of the American Society of Clinical Oncology (ASCO) created waves, a session on value had an equally significant impact as oncologists thronged to hear stakeholder voices define this, as yet abstract, concept of "value" in cancer care. The session brought together a patient representative, an oncologist, an ASCO representative, and a payer.
Predictive Biomarkers Present Promise in Immuno-Oncology
A late-breaking abstract session early on the second day of the annual meeting of the American Society of Clinical Oncology was reserved for the latest data from clinical trials evaluating the new immuno-oncology agents of the PD-1 inhibitor class.