Health Equity, Accessibility Essential to Supporting Women Affected by Hemophilia
Due to often being overlooked as only carriers of hemophilia, the review authors sought to highlight the needs of female caretakers for patients with the disorder and the possibility of women themselves being affected by it.
Polatuzumab Vedotin and R-CHP Appropriate for Untreated DLBCL
Population pharmacokinetic and exposure-response analyses revealed a favorable benefit-risk profilane for the treatment combination of polatuzumab vedotin and rituximab, cyclophosphamide, doxorubicin, and prednisone (R-CHP).
Early Involvement Critical in Treating Immunotherapy-Induced Overlap Syndrome
A series of case studies reveals the importance of early diagnosis and involvement of special teams of clinicians when dealing with potential cases of overlap syndrome, which encompasses myocarditis, myasthenia gravis, and immune checkpoint inhibitor–related myositis.
Liquid Biopsy Whole-Genome Sequencing Optimizes MRD Detection in DLBCL
Using the newly created MAESTRO-Pool tool, whole genome sequencing revealed DNA that could be used to more effectively detect minimum residual disease (MRD) in patients who have diffuse large B-cell lymphoma (DLBCL).
Targeting MACC1 Offers Promising Therapeutic Strategy for PAH
Positive responses seen following experiments involving metastasis-associated in colon cancer 1 (MACC1) indicate that the biomarker can be used to better diagnose and treat patients with pulmonary arterial hypertension (PAH).
Older Patients With DLBCL Face Poor Overall Survival, High Costs With R-GemOx Treatment
Treatment with R-GemOx was associated with significant health care resource utilization, high costs surrounding treatment, and low overall survival in elderly patients with diffuse large B-cell lymphoma (DLBCL).
Venetoclax/Azacitidine Shows Promise for Relapse Prevention in High-Risk MDS and AML
Venetoclax and azacitidine was found safe, but further randomized trials are needed to determine the full extent of the combination’s efficacy in myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML).