Jared is a freelance writer for The American Journal of Managed Care® (AJMC®), and previously worked as a senior editor for HCPLive® at MJH Life Sciences®.
He has an MA from University of Sioux Falls. You can connect with Jared on LinkedIn.
Study Probes COPD Mortality Among People in Low- and Middle-Income Countries
The data largely align with outcomes in high-income countries, with male sex and people with low body weight at particular high risk of mortality.
Study: Brown Adipose Tissue Activation Not Linked With Hypermetabolism in COPD
Measures of metabolism and energy expenditure did not appear to be associated with brown adipose tissue activation in patients with emphysematous chronic obstructive pulmonary disease (COPD).
Autoimmune Diseases, Especially Hypothyroidism, Associated With MDS Risk
Patients with histories of inflammatory bowel disease and systemic lupus erythematosus were also at elevated risks of myelodysplastic syndromes (MDS), the authors found.
Analysis Points to Potential Biomarker for Pediatric PAH
The circulating RNA hsa_circ_0003416 appears to be downregulated in patients with pulmonary arterial hypertension (PAH), according to new research.
New Research Elucidates Role of B Cells in SLE
New subsets of patients with systemic lupus erythematosus (SLE) and new therapeutic targets have been discovered in recent years.
Access Barriers, Self-reliance Cause Patients With COPD to Avoid Prompt Care
Many patients with chronic obstructive pulmonary disease (COPD) do not believe their cases warrant emergency department care.
Range of Factors May Heighten COPD Risk in Nonsmokers
This new study from Spain investigated risk factors for COPD among individuals without a smoking history.
B-Cell Biomarkers Emerging in SLE, but With Important Caveats
Immunoglobulins, free light chains, and beta-2 microglobulin all show promise in tracking systemic lupus erythematosus (SLE) and other autoimmune diseases.
In COPD, Eosinophil Counts Identify Patients Well Suited for ICS Therapy
Patients with high eosinophil counts appeared to benefit from inhaled corticosteroid (ICS) therapy for chronic obstructive pulmonary disease (COPD), while those with low counts did not.
Cytokine Profiles May Signal High Risk of PAH in Patients With Systemic Sclerosis
High-risk patients and patients with a history of pulmonary arterial hypertension (PAH) had significantly different cytokine profiles compared with patients with a low risk of the condition.
In Childhood SLE, Quest for Biomarkers Is Making Progress
Several potential biomarkers have emerged, although most still require significant validation before they can be used in the clinic.
Study Finds Differences in Patients With Both COPD, Heart Failure
However, the differences did not translate into an increased or decreased death rate among the cohort.
Review: New Biomarkers Explored in SLE, but Need Exists for More Validation
A range of new non-serum biomarkers have been identified in recent years, but the authors of a new review urge caution until those markers are further validated.
Early Intervention, Combination Therapy Improve Outcomes in Pediatric PAH
A new report outlines helpful strategies for pediatric patients with pulmonary arterial hypertension, although experts say more research is needed to catch up with advances in the field.
Study Probes Genetic Links Between Asthma, COPD Overlap
A small proportion of patients have symptoms of both asthma and chronic obstructive pulmonary disease. A new report suggests there might be an intermediate phenotype.
Study: Exercise May Decrease Inflammatory Cytokines in Patients With SLE
Serum levels of 4 key cytokines were decreased after 8 weeks of mild exercise, compared with controls.
Comparison of Mexican Ethnic Groups Shows Genetic Factors Heighten SLE Risk
Central Mexican women and women from Yucatán both had risk factors for systemic lupus erythematosus, but they differed in type and degree of risk.
Mortality Prediction Models Perform Poorly in Pneumonic COPD Exacerbations
Two common models, the CURB-65 and BAP-65, had low predictive value in determining which patients with pneumonic chronic obstructive pulmonary disease would not survive.
Study: Metabolic Analysis Could Indicate Skin Involvement in SLE
The report builds upon existing research into metabolic biomarkers, identifying 14 differential biomarkers in patients with systemic lupus erythematosus and skin involvement.
Study: Workplace Pesticide Exposure Linked With COPD Risk
Investigators analyzed 12 categories of workplace agents, but only the composite category of pesticides was found to be linked with developing chronic obstructive pulmonary disease.
Biomarkers Emerging to Track Pulmonary Hypertension, But Picture Remains Complex
Although a number of biomarkers can be used to track features of pulmonary hypertension, no single biomarker is sufficient, according to a new review.
Barriers Hinder Primary Care Providers From Referring Patients With COPD to Pulmonary Rehabilitation
A lack of relationships with pulmonary rehabilitation providers and provider perceptions about patient acceptance serve as limiting factors, new research shows.
New Easy-BILAG Tool Cuts Time, Boosts Accuracy of SLE Progression Tracking
The new one-page tool can be completed about 20 minutes faster than the older form, but it is also more accurate, investigators said.
Questionnaires, PEF Identify COPD in Patients in Low- and Middle-Income Countries
The screening tools were found to be feasible measurements and took just 7.6 minutes to complete on average.
Connective Tissue Diseases, Sepsis Lead to Higher Mortality Risk
According to a recent study, nearly 50% of patients with connective tissue disease, such as lupus, died when sepsis occurred.
Understanding Which Patients With SLE May Also Develop PAH
Predictive markers may make it easier to figure out which patients require the often costly and invasive measures needed to confirm the coronary complication in patients with systemic lupus erythematosus.
Study Suggests 8-OHdG Levels May Serve as PAH Biomarker
In a small study, evidence suggested 8-Hydroxy-2'-deoxyguanosine levels negatively correlated with a test of exercise endurance.
Review: Exercise Endurance Could Be Key Tool to Track COPD Treatment Response
Patients whose endurance increases will likely have a higher quality of life and ability to carry out daily functions, the authors said.
Report Outlines New Risk Factors for Adverse Pregnancy Outcomes in SLE
The report suggests remission and disease activity state alone are not the most important risk factors in pregnant women with well-controlled systemic lupus erythematosus.
Study: Excess Iron Linked With COPD Exacerbation
Evidence suggests higher levels of iron in pulmonary macrophages heightens the risk of infectious exacerbations.