Gianna is an associate editor of The American Journal of Managed Care® (AJMC®). She has been working on AJMC® since 2019 and has a BA in philosophy and journalism & professional writing from The College of New Jersey.
IL Variant May Serve as Genetic Biomarker for Severity, Joint Involvement in Psoriasis
Findings are based on a case-control study carried out in Brazil.
Study Underscores Need for Multidisciplinary Management of Skin Rashes in Patients Completing HCT
Skin rashes are common among patients who complete hematopoietic cell transplantation (HCT).
Digital Approach to Nutritional Education May Improve Nutritional Intake, Boost QOL in Patients With PAH
The pilot program for pulmonary arterial hypertension (PAH) was carried out at a single center in the Netherlands.
Research Shows Lower SES Linked With HS in French Adults
Lower socioeconomic status (SES) was not linked with hidradenitis suppurativa (HS) in minors, but was associated with obesity and tobacco use in this age group.
Even Under Universal Health Care, MM Treatment Access Disparities Persist
Authors concluded more research is needed to understand both patient level and structural barriers to inequitable access to multiple myeloma (MM) care in Canada.
Review Suggests Psoriasis Biologics Not Linked With Adverse Outcomes in Pregnant Patients
Findings are based on a meta-analysis of 51 studies and 739 pregnancies.
Despite Therapeutic Developments in MM, Refractory Patients Face Poor Prognosis: Study
Researchers assessed overall survival outcomes in patients in France.
More Education, Training Needed to Better Incorporate Genome Sequencing for Precision Medicine in Rare Diseases
The decreasing cost of DNA sequencing has contributed to an uptick in genomic sequencing for precision diagnostics in rare diseases.
Researchers Assess Effects of Updated Myeloid Neoplasm Classifications
The new classifications included several major changes and may help identify different subtypes.
Review Identifies Criteria Used to Define Anti–TNF-α Failure in Patients With Psoriasis
It’s estimated around 20% of patients will discontinue their first course of anti–tumor necrosis factor-α (anti–TNF-α) and rates increase over time
Real-World Evidence Finds Low-Dose IL-2 Safe, Well Tolerated in Steroid-Refractory GVHD
Results are based on a study of low-dose interleukin-2 (IL-2) carried out at Dana-Farber Cancer Institute.
Case Study Highlights Importance of Next-Generation Sequencing in Patients With ET
To the authors’ knowledge, the study is the first to include a patient with essential thrombocythemia (ET) and MPL and Type 1 calreticulin gene mutations.
Study Compares Real-world Adverse Events of Methotrexate, Biologics for Psoriasis
Although methotrexate was linked with a higher risk of anemia, it carried risks of kidney and other serious infections similar to those of biologics.
Patient Enablement Linked With Lower Likelihood of Seeking Help for Potential Blood Cancer Symptoms
Higher enablement was associated with being more comfortable to reconsult about persistent or worsening symptoms.
Analysis Finds Value in Safety-Driven Personalized Dosing of Ixazomib
Ixazomib was first approved in the United States in 2015 for relapsed/refractory multiple myeloma.
Research Identifies 4 Predictors of Epilepsy in Children With Complex Febrile Seizures
To stratify the risk of future epilepsy, physicians have historically used lumbar puncture, neuroimaging, and electroencephalography in these patients.
Nonmelanoma Skin Cancer Risks Are Higher When Using Methotrexate for Psoriasis: Study
Patients with psoriasis taking methotrexate are nearly 3 times as likely to develop non-melanoma skin cancer than patients not taking the treatment.
Study Identifies Predictors of PSA Screening for Men in Florida
Results are based off of data from the Florida Behavioral Risk Factor Surveillance System.
Study Assesses Cost Differences for Robot- vs Video-Assisted Thoracoscopic Surgery in Lung Cancer
Researchers took both the learning curve of the new process and the COVID-19 pandemic into consideration.
Research Examines VNS as Treatment for New-Onset Refractory Status Epilepticus
Although the condition is rare and cases are limited, researchers were able to generally conclude vagal nerve stimulation (VNS) serves as a well-tolerated intervention.
Biologic Switching Common Among Patients With Psoriasis in Real-World Setting
After 1 year, overall treatment switch rates were 14.4%, while after 2 years, switch rates were 26%.
Study Suggests Polycythemia Vera Treatments Not Used to Their Full Advantage
Data suggest a substantial reliance on established therapies for polycythemia vera, despite access to all available treatment options.
Researchers Uncover Potential Racial Biases in T2D Risk Prediction Models
Authors offered specific recommendations for improving publishing and adoption of algorithmic processes focused on type 2 diabetes (T2D) going forward.
Tildrakizumab Linked With HRQOL Improvement in Psoriasis in a Real-World Setting
Strict inclusion and exclusion criteria in clinical trials means findings on health-related quality of life (HRQOL) may not be generalizable to the real-world setting.
Study Examines Incidence, Risk Factors for ICI-Related Pneumonitis in NSCLC
Immune checkpoint inhibitors (ICIs) can increase life expectancy among patients who have non–small cell lung cancer (NSCLC), but they also carry the risk of immune-related adverse events.
Low SES Linked With Lower Overall Survival in Early-Onset Prostate Cancer
Researchers suggest socioeconomic status (SES) be considered in prognostic algorithms going forward.
Review Highlights Features, Treatment of Budd-Chiari Syndrome in MPNs
Budd-Chiari syndrome and myeloproliferative neoplasms (MPNs) are rare, which means available data are limited.
Early-Infancy Meningitis Infection Linked With Increased Risk of Epilepsy
New study findings show this risk was higher among children born prematurely or whose mother was classified as having low socioeconomic status.
Study Examines Effects of COVID-19 Social Isolation on Older Patients With T1D
The study identified 3 themes related to diabetes self-care in patients who have type 1 diabetes (T1D), including emotional stress and anxiety and concerns regarding the COVID-19 pandemic.
Study Examines Axi-Cel Use for Follicular Lymphoma Management
Researchers compared chimeric antigen receptor T-cell therapies axicabtagene ciloleucel (axi-cel) and tisagenlecleucel.