Allison Inserro

Finerenone slowed chronic kidney disease (CKD) progression by 18% and cut cardiovascular (CV) events by 14%, according to phase 3 trial results.

The study describes how RNA sequencing and DNA sequencing for selected genes were performed simultaneously to evaluate gene expression and alterations in order to predict tumor origin.

Attendees at the Academy of Managed Care Pharmacy (AMCP) Nexus 2020 meeting will hear a keynote from a surgeon who has become more visible over the past year and a half discussing what he says are “structural problems” behind the cost of US health care.

Nearly 10,000 deaths from non–small-cell lung cancer (NSCLC) were likely delayed between 2014 to 2016, the researchers calculated.

Orphan drug spending to treat rare conditions in children is increasingly burdening payers and families, a recent study said.

The researchers, from a medical genetics firm, said the findings illustrate the usefulness of germline analysis for the right patient.

A recent study about the impact of spinal muscular atrophy (SMA) on patients and caregivers may help to illustrate the impact of future improvements as new therapies take hold, but more targeted SMA quality-of life-outcome measures may be needed to fully the changes.

The research looked at inpatients with migraine on erenumab, and overall, found that the incidence was similar to patients in real-world settings.

There is no question that posttraumatic headache and migraines are related, said the head of neurology research at the Mayo Clinic’s Arizona campus; the unknown issue is to what extent they are related.

The entry of a new class of migraine therapies has created a new wave of excitement. A presentation at the Migraine Trust International Symposium reviewed what clinicians now know about calcitonin gene-related peptide (CGRP) blockers.

At a session Tuesday at the Migraine Trust International Symposium, one presentation delved into findings published this year in medication overuse headaches, prevention, and pathophysiology of migraine as well as cluster headaches.

Two neurologists discuss what is known and unknown in switching patients with migraine from one calcitonin gene-related peptide (CGRP) inhibitor to another.

President Donald Trump is showing symptoms after testing positive for the virus that causes coronavirus disease 2019. He received an experimental antibody cocktail and was taken to Walter Reed Medical Center.

Efficacy and safety of atezolizumab as first-line therapy for metastatic non–small cell lung cancer (NSCLC) with high levels of PD-L1 expression is not known, the authors said.

The study is part of Moderna’s larger trial to find a vaccine to prevent coronavirus disease 2019, which puts older adults, who have weaker immune responses, at a higher risk of more severe illness and death.

A study looking at older adults with chronic pain found no significant difference in cognitive performance when comparing them with matched patients who did not use medical cannabis.

Researchers hope that a more targeted retinoid acid X receptor compound could repair myelin without the adverse effects seen in every patient in this trial, which tested an already approved cancer drug.

The results were shared as part of the MSVirtual2020: 8th Joint ACTRIMS-ECTRIMS Meeting, which is concluding Saturday with a special session about coronavirus disease 2019 (COVID-19).

The announcement comes just 6 weeks before the Supreme Court is set to hear oral arguments in Texas v Azar, upon which the future of the Affordable Care Act (ACA)—which counts among its many provisions protection for patients with preexisting conditions—hinges, and which the administration is trying to get overturned.

To mark the 25th anniversary of the journal, each issue in 2020 will include an interview with a health care thought leader. The October issue features a conversation with Kavita K. Patel, MD, MS, nonresident fellow at The Brookings Institution and editorial board member of AJMC®.

FDA will review the first chimeric antigen receptor (CAR) T cell immunotherapy for the treatment of multiple myeloma (MM) in adults who have not responded or have relapsed after at least 3 other therapies.

The KRAS mutation occurs in 13% of non–small cell lung cancers (NSCLC) and leads to worse outcomes in NSCLC.

The survey was released to mark Pain Awareness Month.

The findings have implications for patient self-management of their chronic disease, and clinicians should screen for worsened cognitive function, the researchers wrote.

Patients with advanced colon cancer who drank 4 or more cups of coffee a day had 36% improved survival odds.

More than half of the patients in this study, with either non–small or small cell lung cancer, experienced changes in their treatment plan during the coronavirus disease 2019 pandemic this spring.

To the extent that some factors are modifiable, the takeaway for clinicians is to encourage their patients with multiple sclerosis (MS) to adopt healthy habits.

The drug, mastinib, reduced the chance of a confirmed disability progression by 37% in phase 2b/3 study results.

Pain, fatigue, and depression are 1 cluster of symptoms afflicting 1 in 13 survivors of prostate cancer, according to a recent study.

Post hoc data from 2 late-stage studies about siponimod, sold as Mayzent by Novartis, illustrated improved cognitive processing speed and delayed time to disability in multiple sclerosis.