Segment 6 - Personalized Medicine

Dr Crawford said that in order to pick the appropriate treatment for a diagnosed patient with prostate cancer, it is important to think outside of the box. The National Comprehensive Cancer Network (NCCN) and the American Urological Association (AUA) offer castration-resistant prostate cancer (CRPC) guidelines that serve as the best guideline for payers. They offer the best level-1 evidence for making decisions. However, Dr George said the NCCN guidelines are not helpful to clinicians. “For clinicians out there it’s not a challenge to say which therapy I should use, but when should I switch, and that’s where we offer very little help,” said Dr George.