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Dr Steven R. Feldman on the Effect of Metabolic Syndrome on Treatments for Psoriasis
Steven R. Feldman, MD, PhD, professor of dermatology, Wake Forest School of Medicine, discusses how some drugs for psoriasis are less effective in the presence of metabolic syndrome.
Steven R. Feldman, MD, PhD, professor of dermatology, Wake Forest School of Medicine, discusses how some drugs for psoriasis are less effective in the presence of metabolic syndrome.
TranscriptHow does the presence of metabolic syndrome impact the efficacy of psoriasis treatment?
The presence of metabolic syndrome does affect the efficacy of psoriasis treatments, or at least it’s associated with worse efficacy. So, there was a study done that found people with metabolic syndrome had high rates of failing their treatment for their psoriasis. It may help to use medicines that are either more potent or don’t care whether you have metabolic syndrome.
Are there any data to help clinicians select an effective psoriasis treatment for patients who also have metabolic syndrome?
There are some data that tell us what drug might be more effective for someone with metabolic syndrome. Some of the drugs are dosed based on weight. And for those drugs, the heavier patients do well on a higher dose—and we have the data to support that. Other drugs may not be weight based, and they may have some tendency to be less effective in people who are more obese. One of the drugs, tildrakizumab, had some data showing it worked equally well in patients who either had or did not have metabolic syndrome.
Frameworks for Advancing Health Equity: Urban Health Outreach
May 9th 2024In the series debut episode of "Frameworks for Advancing Health Equity," Mary Sligh, CRNP, and Chelsea Chappars, of Allegheny Health Network, explain how the Urban Health Outreach program aims to improve health equity for individuals experiencing homelessness.
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Tackling Health Inequality: The Power of Education and Experience
April 30th 2024To help celebrate and recognize National Minority Health Month, we are bringing you a special month-long podcast series with our Strategic Alliance Partner, UPMC Health Plan. Welcome to our final episode of this limited series and our conversation with Janine Jelks-Seale, MSPPM, director of health equity at UPMC Health Plan.
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