April 27th 2025
New research explores the complex relationship between female infertility and gynecological cancers, revealing minimal links and emphasizing the need for further studies.
Lessons from the early days of chimeric antigen receptor (CAR) T-cell therapy remain fresh as Kite Pharma prepares for the FDA to act on its supplemental biologics license application for use of axi-cel as second-line therapy in relapsed or refractory large B-cell lymphoma. A target action date is set for April 1, 2022.
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Real-world Study Identifies Several Predictors of Risankizumab Response in Psoriasis
February 14th 2022Risankizumab was shown to be highly effective in patients with moderate to severe psoriasis of tertiary medical centers in Italy, in which response was found to be significantly affected by smoking, and incidence of psoriatic arthritis.
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A statement from NCCN’s Advisory Committee on COVID-19 Vaccination and Pre-exposure Prophylaxis said that the panel “endorses vaccination for all eligible persons based on FDA-approved indications or emergency use authorization” and emphasized the need for everyone to be fully vaccinated—including third doses.
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Early Response to Biologics Linked With Stable Long-term Efficacy in Psoriasis
February 12th 2022More patients with moderate-to-severe psoriasis were found to be early responders to ixekizumab vs ustekinumab; all those who achieved early response were associated with stable skin clearance long-term.
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Postsurgery Factors Linked With Disease Control in Chronic Rhinosinusitis With Nasal Polyps
February 8th 2022Patients with chronic rhinosinusitis with nasal polyps who had elevated serum amyloid A (SAA) levels were more likely to achieve disease-controlled status vs those with low SAA levels after endoscopic sinus surgery.
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Payers, Value-based Care Policies Impact Biosimilar Adoption, Cardinal Health Report Finds
February 8th 2022Cardinal Health's report, “2022 Biosimilars Report: The U.S. Journey and Path Ahead,” outlines how biosimilars will move beyond their comfort zones in oncology and rheumatology and more boldly into therapeutic areas such as ophthalmology and diabetes care.
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mRNA COVID-19 Vaccines Safe Among Patients With Cancer History
February 7th 2022A study from investigators at Fox Chase Cancer Center sought comparative outcomes data on adverse reactions from COVID-19 vaccination among patients with a history of cancer and those undergoing treatment and found equivalent safety outcomes.
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Association of Opioid Utilization Management With Prescribing and Overdose
Opioid utilization management in Medicare was associated with mixed effects on opioid prescribing, and prior authorization was associated with a decreased likelihood of subsequent overdose.
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Sinonasal CT Scores May Predict Prognostic Features of Chronic Rhinosinusitis With Nasal Polyps
February 2nd 2022Sinonasal CT scores were associated with several prognostic features in the disease course of chronic rhinosinusitis with nasal polyps, including blood eosinophil counts and risk of relapse after endoscopic sinus surgery.
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Pfizer/BioNTech expected to file for emergency use designation of its COVID-19 vaccine in young children aged 6 months to 5 years; Environmental Protection Agency (EPA) sets limits on power plant emissions of mercury and other hazardous pollutants; Black women at disproportionately greater risk of late-stage cervical cancer diagnosis and death.
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COA Survey: Practices Find OCM a Success; Some Added Services May Be at Risk
January 31st 2022The Oncology Care Model (OCM) is set to expire June 30, 2022. With no successor on the horizon, respondents to a recent survey by the Community Oncology Alliance (COA) say features such as dedicated navigators and weekend appointments could be reduced or lost if revenues that supported them are eliminated.
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Dr Edward W. Cowen Addresses Current Management of Pustular Psoriasis
January 30th 2022Edward W. Cowen, MD, MHSc, senior clinician and acting branch chief, Dermatology Branch, National Institutes of Health, discusses treatment considerations for patients with different types of pustular psoriasis.
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