April 28th 2025
New research suggests classical biomarkers cannot discriminate between refractory and non-refractory rheumatoid arthritis.
Investigation Finds Statistical Relationship Between Heart Failure, Cancer Incidence
June 28th 2021Research that will be presented at Heart Failure 2021 shows patients with heart failure may have a greater incidence of several types of cancer and that this chance is even higher in women vs men.
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TKI Selection in CML: Clinical, Economic Burden and Long-term Outcomes
June 18th 2021Two posters presented at the European Hematology Association 2021 Virtual Congress evaluated tyrosine kinase inhibitor (TKI) selection in the front line and compared first-generation to second-generation TKIs.
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MedPAC to Congress: Change MA Benchmarks, Slow Down on APMs
June 18th 2021The Medicare Payment Advisory Commission (MedPAC) suggested several changes to Medicare Advantage (MA) plan benchmark calculations, with the intent to generate yield savings for Medicare, and urged CMS to streamline alternative payment model (APMs) where it can.
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Risk Predictive Model May Aid Providers in Diagnosing IPA in AECOPD
June 17th 2021A study evaluating independent risk factors for invasive pulmonary aspergillosis (IPA) in hospitalized patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) validated a potential model that could help providers diagnose IPA earlier.
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The Large Placebo Effect in Cough Presents Major Challenges for Antitussive Trials
June 12th 2021New antitussive trials are challenged by large placebo effects and the risk of the trial being unblinded due to adverse effects, explained Ron Eccles, BSc, PhD, DSc, emeritus professor at Cardiff University.
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Zanubrutinib Improves Outcomes Compared With Ibrutinib in R/R CLL/SLL, ALPINE Study Shows
June 11th 2021An interim analysis of the phase 3 ALPINE study demonstrated that zanubrutinib has a superior response rate, improved progressive-free survival, and lower rate of atrial fibrillation/flutter compared with ibrutinib in patients with relapsed/refractory chronic lymphocytic leukemia/ small lymphocytic leukemia (CLL/SLL).
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Clinical Trial Results Need to Be Supplemented With Real-World Data in Multiple Myeloma
June 11th 2021The populations represented in randomized controlled trials often do not match the populations being treated in the real world due to eligibility criteria, which can be challenging when translating those results to real-world decisions, explained speakers during a session at the European Hematology Association 2021 Virtual Congress.
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COVID-19 and Clinic Workflow Optimization Using Lean Six Sigma
June 10th 2021The authors report an approach of outpatient clinic workflow reorganization utilizing simple, inexpensive measures to improve patient engagement and experience in addition to providing a safe setting for patients for clinic visits in the wake of COVID-19.
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Dr Ola Landgren Highlights Safety and Efficacy of Adding Daratumumab to Combination Therapy in MM
June 8th 2021Daratumumab will likely become a part of most combination therapies for patients with newly diagnosed multiple myeloma (MM) because it safely adds efficacy, according to Ola Landgren, MD, PhD, of the University of Miami and Sylvester Comprehensive Cancer Center.
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EHA Preview: Advances, Outcomes in CAR T-Cell Therapies and Management Challenges
June 8th 2021With 5 chimeric antigen receptor (CAR) T-cell therapies approved by the FDA, and 299 agents in the pipeline, it’s no surprise that the virtual meeting of the European Hematology Association (EHA) will have a heavy presence of CAR T research being presented in sessions and posters.
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“Practice-Changing” Results Seen for Pembrolizumab in Adjuvant Setting in Renal Cell Carcinoma
June 7th 2021The study's lead author said researchers have searched for a generation for an effective therapy to give to high-risk patients with renal cell carcinoma after initial surgery for the tumor.
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ASCO’s Dr Lori Pierce on Equity in Cancer Care: “History Has Its Eyes on Us”
June 5th 2021Equality in cancer care is not sufficient, said Lori Pierce, MD, FASTRO, FASCO, a radiation oncologist from the University of Michigan and president of the American Society of Clinical Oncology (ASCO). Equity—which means that patients have similar outcomes, regardless of circumstance—is harder to achieve.
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Dr Peter Dicpinigaitis Highlights Key Presentations at the American Cough Conference
June 4th 2021The 2-day meeting of the American Cough Conference will cover new developments in the treatment of cough, as well as insights into the mechanisms and management of cough, said Peter Dicpinigaitis, MD, chair of the American Cough Conference.
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Contributor: A Renewed Call to Arms to Defeat HIV/AIDS on Its 40th Anniversary
June 2nd 2021On the eve of the 40th anniversary of the CDC’s first report on what would become known as HIV/AIDS, Perry N. Halkitis, PhD, MS, MPH, sends out an urgent call to continue this fight and rededicate resources to finding a cure.
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Contributor: Maintaining the Doctor-Patient Connection During the COVID-19 Pandemic
May 29th 2021Christine Ko, MD, professor of dermatology and pathology at Yale University, reflects on her use of telehealth and how it allowed her to establish and maintain emotional connections with her patients, all at high risk of skin cancer.
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Dr Michael Gottlieb Reflects on the Early Days of the AIDS Epidemic
May 27th 2021In the June 5, 1981, issue of the Morbidity and Mortality Weekly Report from the CDC, a brief 3-page report appeared describing 5 rare cases of Pneumocystis carinii pneumonia among 5 homosexual men in Los Angeles. Our full Q&A with the lead author on that report, Michael Gottlieb, MD, will appear next week. Below is a video preview.
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Oncologists Highlight Treatment, Patient Attributes That Impact Decision-making for CLL
May 22nd 2021With a variety of treatments available for chronic lymphocytic leukemia (CLL), a disease that is extremely heterogeneous, clinicians are faced with a challenging task to choose the right treatment for a patient.
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Matching Right Patients to Right Drugs Is Key With New Entrants to Heart Failure Market
May 18th 2021Sessions, posters, and late-breaking trials at the American College of Cardiology’s 70th Scientific Session offer updates on vericiguat, SGLT2 inhibitors, sacubitril/valsartan, and heart failure therapies still in the pipeline.
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