April 29th 2025
Jon Giles, MD, speaks to the power of personalized medicine and multidisciplinary care to enhance treatment for patients with rheumatoid arthritis (RA).
TNF Inhibitors Show Real-world Efficacy on QOL of Patients With Nail Psoriasis, PsA
November 29th 2021Patients with concomitant psoriasis, nail psoriasis, and psoriatic arthritis (PsA) exhibited significant improvements in joint and disease severity symptoms, as well as quality of life (QOL) after 3 months of treatment with tumor necrosis factor-α (TNF) inhibitors of adalimumab, etanercept, or infliximab.
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President Joe Biden will provide an update today on his administration’s response to the Omicron COVID-19 variant; marked rise in lung transplants for patients with COVID-19 sparks ethical questions; an independent panel of experts will advise FDA tomorrow on the use of Merck’s COVID-19 antiviral pill.
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Atopic Dermatitis Severity, Age at Diagnosis May Increase Risk of Ophthalmic Diseases
November 25th 2021Moderate-to-severe disease, childhood onset, and systemic treatments were all associated with a greater risk of conjunctivitis in patients with atopic dermatitis, whereas use of soft and hard contact lenses were linked with risk of keratitis.
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Risk of Severe COVID-19 Heightened in Patients With Obstructive Sleep Apnea
November 24th 2021In Icelandic patients, obstructive sleep apnea were associated with a 2-fold increased risk of severe COVID-19 that required hospitalization or led to death after accounting for obesity and other comorbidities.
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George Van Antwerp: Specialty Drugs Rely on Personalization for Optimal Outcomes
November 24th 2021The high cost of specialty drugs makes it important to use companion diagnostics and other tests to make sure the drug is going to the right patient, said George Van Antwerp, MBA, managing director, Deloitte Consulting.
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Machine Learning Approach Finds Several Severity-Associated Factors in Atopic Dermatitis
November 23rd 2021Findings of a machine learning-based deep phenotyping approach found a myriad of factors associated with severe disease in atopic dermatitis, including age between 12 and 21 years or older than 52 years, lack of physical activity, and incidence of alopecia areata.
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Achieving Equitable Breast Cancer Care: Clinical Trials, Mental Health, and Digital Therapeutics
November 23rd 2021Discussions regarding health equity and access to care have long been implicated in breast cancer. Here, key opinion leaders discuss the latest progress in clinical trial access, digital therapeutics, and other efforts that aim to ameliorate these care gaps.
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With No Replacement for OCM on Horizon, Oncology Practices Ask: What Now?
November 22nd 2021The announcement of a "strategic refresh" for payment models under the Center for Medicare and Medicaid Innovation offered no details on what practices should expect when the Oncology Care Model (OCM) expires in 2022.
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Contributor: Congress Must Do More to Cover Nonopioid Alternatives
November 21st 2021Preventing addiction is key to ending the opioid epidemic—2020 alone saw more than 93,000 overdose deaths—as are expanding access to treatment, promoting recovery, and building a multifaceted strategy that incorporates nonopioid alternative and their coverage by providers. Although appropriate in certain situations, opioids are not a one-size-fits-all approach.
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Dr Daniel Greer on Emergence of CBT as First-line Treatment for Chronic Insomnia
November 20th 2021Daniel Greer, PharmD, BCPP, clinical assistant professor, Rutgers Ernest Mario School of Pharmacy, discusses the use of cognitive behavioral therapy (CBT) as a first-line treatment for chronic insomnia and barriers limiting its use.
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Dr Robert Hopkin on Emerging Therapeutic, Technological Advancements in Fabry Disease
November 19th 2021Robert J. Hopkin, MD, clinical geneticist, Cincinnati Children's Hospital Medical Center, discusses current and emerging therapeutic and technological advancements in the management of Fabry disease.
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Bariatric Surgery Reduced Risk of Major Adverse Liver, CV Outcomes in Patients With NASH
November 18th 2021Patients with nonalcoholic steatohepatitis (NASH) and obesity had a reduced risk of major adverse liver outcomes and major adverse cardiovascular (CV) events after they underwent bariatric surgery compared with patients who did not have surgery.
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Sacubitril/Valsartan Treatment for HFpEF Shown to Reduce NT-proBNP Levels
November 18th 2021Wanting more data on the benefits of sacubitril/valsartan vs renin angiotensin system inhibitor background therapy, investigators conducted a large randomized study among persons with heart failure with preserved ejection fraction (HFpEF).
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Dr Jonathan Silverberg on Potential Benefits, Challenges of JAK Inhibitor Use in Atopic Dermatitis
November 17th 2021Jonathan Silverberg, MD, PhD, MPH, associate professor of dermatology, director of clinical research and patch testing, George Washington University School of Medicine and Health Sciences, explains efficacy and safety implications of JAK inhibitor use for atopic dermatitis.
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Guselkumab Linked With Long-term Improvement of Joint Manifestations, Disease Activity in PsA
November 17th 2021Phase 3 findings of the DISCOVER-2 trial presented at the 2021 American College of Rheumatology Annual Meeting indicated that guselkumab (Tremfya) provided long-term improvement in joint manifestations, disease activity, and physical function among patients with psoriatic arthritis who had no prior biologic treatment.
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HRQOL Decreased During and Immediately After CAR T-Cell Therapy for DLBCL
November 16th 2021Prior to chimeric antigen receptor (CAR) T-cell therapy for relapsed/refractory diffuse large B-cell lymphoma (DLBCL), patients experienced a decrease in health-related quality of life (HRQOL), which was further impaired during and immediately after CAR T therapy.
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Teprotumumab Benefits Patients With Mild Inflammation and Real-world Adherence Remains High
November 15th 2021Posters presented at the American Academy of Ophthalmology 2021 annual meeting showed that even patients with mild inflammation with their thyroid eye disease benefitted from teprotumumab and that real-world adherence was consistent with the pivotal clinical trials.
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Teprotumumab, Enhanced Monofocal IOLs Among Hot Topics at AAO 2021
November 15th 2021Among many presentations during a hot topics session at the American Academy of Ophthalmology 2021 annual meeting, speakers discussed the first FDA approved therapy for thyroid eye disease and the latest in enhanced monofocal intraocular lenses (IOLs).
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Ophthalmology at Crossroads for Information Technology, AI
November 14th 2021The field of ophthalmology had already been moving toward telehealth and artificial intelligence (AI) before the COVID-19 pandemic, but these changes are being accelerated now, making it crucial for ophthalmologists to learn to adapt.
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Pathologists Discuss Actionable Mutations and Testing in Metastatic Breast Cancer
November 14th 2021Genetic profiling in recurrent and advanced breast cancer can yield actionable, smoking-gun biomarkers, Stanford Cancer Institute pathologists explained at the National Comprehensive Cancer Network 2021 Virtual Congress: Biomarkers in Solid Tumors.
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Posters at AAO 2021 Analyze ED Utilization for Nonemergency Ophthalmic Conditions
November 13th 2021Emergency department utilization for nonemergent ophthalmic conditions is on the rise in the United States, but presentation types vary significantly based on patient demographics, according to 2 posters presented at the American Academy of Ophthalmology (AAO) 2021 meeting.
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Dr William Katowitz Discusses Pediatric Ophthalmic Surgical Decisions
November 13th 2021Surgical decisions with children who have ophthalmic conditions need buy in from parents, but also the children as they get older, said William Katowitz, MD, attending surgeon in the Division of Ophthalmology at Children's Hospital of Philadelphia.
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