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The incoming Biden administration announces plans to rapidly release most available vaccine doses against coronavirus disease 2019; the Trump administration approves the first Medicaid block grant in Tennessee; pharmaceutical executives and trade groups condemn last week’s pro-Trump riots on Capitol Hill.

Every week, The American Journal of Managed Care® recaps the top managed care news of the week, and you can now listen to it on our podcast, Managed Care Cast.

New study findings may pave the way for research into the prognostic value of white matter lesions in heart failure and the impact that HF therapies have on them.

Daniel F. Hayes, MD, offers definitions and an algorithm for clinicians to define clinical utility.

Among patients who have chronic obstructive pulmonary disease (COPD), the pathophysiology for disturbed sleep consists of physiological changes, ventilatory disturbances, and inflammation.

Changes in circulating tumor DNA (ctDNA) are indicative of treatment response in early-stage breast cancer, pointed out Alexey Aleshin, MD, senior medical director of Oncology at biotech giant Natera.

A recent study explored how patients with Parkinson disease who suffer from constipation are more likely to have other nonmotor symptoms than patients without constipation.

The findings could lead to a precision medicine approach to prostate cancer screening.

A study links the size of cysts associated with endometriosis with coexistent ovarian cancer.

Amid speculation that total blood counts may be associated with heart failure prognosis, researchers find that higher levels of platelet distribution width could be used to predict a worse prognosis for heart failure.

The FDA decision on dapaglifozin for CKD is expected in the second quarter of 2021.

A review explored the potential role of eosinophils and their mediators in the pathophysiology of chronic rhinosinusitis (CRS) subtypes.

The American Hospital Association (AHA) asks HHS Secretary Alex Azar to expedite the rollout of coronavirus disease 2019 vaccines; CDC data show accelerated cardiac aging among cancer survivors; a study examines new targets for reducing adolescent access to opioids.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Researchers conducting a large epigenome-wide association study identified several methylation sites associated with hereditary transthyretin amyloidosis (hATTR), a rare, life-threatening disorder caused by amyloidogenic coding mutations in the TTR gene.

This week, the top managed care news included FDA advising against changes to vaccine dose schedules; drop in mammography screenings during the first months of the pandemic; first anti-TIGIT therapy granted Breakthrough Therapy designation by the FDA.

Patients with psoriasis may be more likely to have additional autoimmune disorders, including vitiligo, diabetes, autoimmune thyroiditis, rheumatoid arthritis, and inflammatory bowel disease.

Patients with heart failure should be prioritized during vaccine rollout because of increased mortality risks reportedly associated with coronavirus disease 2019 (COVID-19).

A recent meta-analysis appearing in Journal of Cancer indicates a connection between minimal residual disease (MRD)–positive status and worse progression-free survival (PFS) and overall survival (OS) following induction and consolidation therapies.

Complete response to first-line therapy, as determined by the International Working Group 2006 response criteria, can be used as a surrogate end point for overall survival in higher-risk patients with myelodysplastic syndromes (MDS), according to a study published in Cancer Medicine.

A Democratic majority in the United States Senate could mean changes in health care policy are to come; CDC says benefits of the coronavirus disease 2019 (COVID-19) vaccine outweigh risks of allergic reactions; Los Angeles faces a shortage of oxygen.

Michael Snyder, PhD, professor and chair of genetics at the Stanford University School of Medicine, discusses the ways in which precision health measurements can aid physicians in detecting and better managing diabetes.

Age, renal disease, and suboptimal myeloma control were among the many factors identified in a recent study as increasing the risk of death from coronavirus disease 2019 (COVID-19) for patients being treated for multiple myeloma (MM).

Telehealth services have saw a spike in October as COVID-19 cases continued to rise, as seen in claims tracked by FAIR Health.

Study findings, published in Frontiers in Medicine, underscore the importance of metabolic profiling for discovering candidate screening biomarkers for interstitial lung disease (ILD) in rheumatoid arthritis.

Addressing the social health needs of those ill with coronavirus disease 2019 (COVID-19) is a challenge for providers and health care systems. On this episode of Managed Care Cast, we speak with Bechara Choucair, MD, senior vice president and chief health officer for Kaiser Permanente, who discusses the organization's guide that walks clinicians through considerations to keep in mind when screening patients in order to improve health outcomes as well as reduce community transmission.

The coronavirus disease 2019 (COVID-19) pandemic disrupted many mental health services for children; a study on the long-term effects of COVID-19 will soon kick off; a $13-billion deal has been struck for UnitedHealth to buy Change Healthcare.

Pain is a subjective response with multiple features and components, said Frank Porreca, PhD, professor of pharmacology and anesthesiology at the University of Arizona and a member of the Department of Collaborative Research at Mayo Clinic in Arizona.

Despite limited resources to combat the coronavirus disease 2019 pandemic, collaborative efforts among the government, health plans, and providers in Puerto Rico exemplify how care can be better optimized in communities in the United States impacted by disparities in health care services.