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CMS' Medicare Shared Savings Program proposal would make substantial changes to the benchmarking methodology for accountable care organizations.

A survey has revealed gaps in HIV providers’ knowledge of the Affordable Care Act. However, despite these gaps, the majority of surveyed providers expressed belief that Medicaid expansion would improve both HIV outcomes and general outcomes for patients with the disease.

A series of experiments identified both "good" and "bad" gut bacteria, suggesting possible treatments for obesity.

A new issue brief from the Henry J. Kaiser Family Foundation reports on healthcare and recovery efforts 1 year after Hurricane Maria struck Puerto Rico and the US Virgin Islands (USVI), with residents still struggling to regain what they lost, a lack of capacity due to damaged facilities or lack of staff, and financing woes that will make moving forward difficult if they are not addressed.

Amgen’s pipeline drug AMG 420, a bispecific T-cell engager (BiTE) for the treatment of patients with relapsing/refractory multiple myeloma (RRMM), has found positive preliminary results in a phase 1 trial.

States, communities, and organizations received more than $1 billion in grants from HHS to help them fight the opioid crisis; a preliminary study has found that children conceived through infertility treatments could be at higher risk for cardiovascular disease; the State of California is alleging that AbbVie boosted sales of Humira through kickbacks to prescribers and a network of nurse ambassadors.

The Multiple Sclerosis-Secondary Progressive Multi-Arm Randomization Trial (MS-SMART) is the first multiarm trial designed specifically to address the unmet need for further identification of neuroprotective drugs in secondary progressive multiple sclerosis.

A Mayo Clinic team critiqued the 2018 update to the Global Initiative for Chronic Obstructive Lung Disease guidelines, recommending several changes to the next update.

Despite efforts over the past decade to wring more value from healthcare in an effort to contain spending, healthcare spending as measured by those with employer-sponsored health insurance rose by 44% over the past decade, according to a new analysis from the Health Care Cost Institute (HCCI).

A new report contradicts CMS’ claim that the Medicare Shared Savings Program increased Medicare spending by $344 million from 2013 to 2015. The new analysis finds that accountable care organizations (ACOs) actually reduced federal spending by $542 million after accounting for shared savings payments earned.

In their study published in Nature Communications, the authors mapped out the epigenomic profiles of rheumatoid arthritis (RA) and osteoarthritis for the first time to provide insight on RA-specific pathways and transcription factor motifs. A surprising discovery was that the Huntingtin-interacting protein-1 may play a role in the pathogenesis of RA.

While it is well understood that psychological distress is a major side effect of cancer and its treatment, and that stress can have a strong impact on patients’ quality of life, a new study indicated that stress is linked with markers of more advanced disease in patients with chronic lymphocytic leukemia (CLL), the most common form of leukemia among adults.

A study says it found a link between bone mineral density and sleep onset latency in an elderly population.

With healthcare costs growing, a bipartisan group of senators has unveiled draft legislation that would protect patients from surprise bills and prevent medical bankruptcies; at least 17 hog-waste lagoons may have released feces and urine into flood waters in North Carolina, putting people at risk of viruses, parasitic infections, and rashes; African Americans accounted for fewer than 5% of patients in 24 trials for cancer drugs approved since 2015.

A study found that testosterone replacement therapy reduced the risk of respiratory hospitalizations in men with chronic obstructive pulmonary disease (COPD).

The bill is part of President Donald Trump's blueprint to rein in prescription drug prices, and advocates see it as a small step in the right direction.

Researchers examining how well integrated practice units (IPU) are implemented across 7 cancer centers in Europe found there was no clear, consistent strategy for developing and implementing IPUs, in an analysis that focused mostly on breast cancer clinical pathways.

With general consensus that those 70 years and older should not be routinely screened for prostate cancer, researchers argue that their study results identify an area for cutting low-value services to reduce healthcare spending.

Researchers determined that the current drug pipeline is unlikely to produce any highly effective vaccines for HIV, tuberculosis, or malaria, which could be important for controlling the spread of these diseases.

While the pathogenesis of autoimmune myelofibrosis is not completely understood, in patients with systemic lupus erythematosus, it may be triggered by circulating immune complexes that induce megakaryocytes to release platelet-derived growth factor.

Healthcare costs in America are seeping into nonhealthcare companies’ earnings announcements. None of those companies discussed healthcare this time last year.

The Senate passed a massive opioid bill 99-1, but public health experts and first responders are concerned it won’t do enough to stop the crisis; pharmaceutical companies with manufacturing plants in North Carolina, South Carolina, and Virginia put emergency plans in place last week as Hurricane Florence bore down to avoid shortages of drugs and vaccines; the cannabis industry is booming, and one of the fastest growing group of users are people over age 50.

Lower socioeconomic status is associated with poor survival in lymphoma.

A phase 2 clinical trial of a surgical procedure called targeted lung denervation to open blocked airways in patients with chronic obstructive pulmonary disease (COPD) showed that it reduced problems associated with the disease.

CMS said that it is proposing to reduce regulations on hospitals and ambulatory surgery centers in a move it estimates will save $1.12 billion annually as part of its “Patients Over Paperwork” initiative.

The FDA announced a new, 4-pronged approach to the growing problem of antimicrobial resistance (AMR), as it unveiled a 2019 strategic plan that envisions innovative payment strategies in an effort to spur pharmaceutical companies to develop new antibiotics.

Researchers pinpointed the characteristics of asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) causing a greater disease burden than either condition alone.

The approval comes 6 months after the 2 companies fist made an announcement of the proposed merger.

The survey of more than 340 women revealed an overwhelming belief that people with migraine are dismissed as exaggerating their symptoms and that employers don't understand the burden of migraine on their employees.

Last week, the FDA granted priority review to a new supplemental Biologics License Application for pembrolizumab (Keytruda) as a monotherapy for first-line treatment of locally advanced or metastatic nonsquamous or squamous non–small cell lung cancer (NSCLC) in patients whose tumors express PD-L1 without EGFR or ALK mutations.