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A case report has revealed that clozapine with intermittent colony-stimulating factors helped treat leukopenia and neutropenia in a patient with chronic paranoid schizophrenia who responds only to clozapine.

Five unproven or potentially risky treatments have raised millions of dollars through crowdfunding campaigns since 2015; just 10 minutes of mild exercise can have an immediate impact on brain function; the Maine Attorney General’s Office has filed a brief supporting a lawsuit accusing Governor Paul LePage of breaking the law by trying to block Medicaid expansion.

A German study examined whether multidisciplinary inpatient treatment for chronic neuropathic pain leads to improvement of pain in outcome and psychological variables at posttreatment and 3-month follow-up.

The FDA’s approval of dupilumab, already approved for severe eczema, for asthma makes it the second biologic for the incurable lung disease.

Speakers at the National Committee for Quality Assurance’s Quality Talks meeting discussed challenges to improving healthcare delivery, such as changing behaviors, moving care outside of institutions, and rebuilding trust among marginalized populations.

The FDA announced it will consider ways to make naloxone more broadly available, including the possibility of coprescribing the opioid overdose antidote with some or all opioid prescriptions. In addition, CMS said it was creating a new care model to care for pregnant and postpartum Medicaid beneficiaries with opioid use disorder.

A phase 3 trial recently investigated if nanoparticle albumin-bound paclitaxel enhances the treatment of atezolizumab in unresectable locally advanced or metastatic triple-negative breast cancer.

Postoperative and preoperative start of low molecular weight heparin (LMWH) does not change the outcome of mortality or risk of reoperation in patients with hip fractures treated with osteosynthesis, according to a recent study.

The Trump administration will allow small employers to use tax-free health reimbursement accounts (HRAs) to provide health coverage to workers; the number of fatal drug overdoses nationwide has fallen for 6 consecutive months; a pilot study with a small sample size of 8 people discovered that microplastics can make their way into the human gut.

In reponse to rising healthcare prices and emergency department (ED) visits, insurers have implemented policies that apply financial disincentives for ED visits that could presumably be cared for in alternative settings. However, 87.9% of commercially insured ED visits present with the same primary symptoms as visits that result in nonemergent diagnoses.

A recently published cohort study with a register-based follow-up of some individuals from the Danish general population sought to investigate whether smokers are at an increased risk for developing MPNs versus those who have never smoked.

Approximately one-third of all US healthcare payments in 2017 were tied to alternative payment models, with the remaining still tied to fee for service. The findings of the Health Care Payment Learning and Action Network report highlighted that even as payments move to value-based models, more spending in models with risk is needed.

The Trump administration Monday moved to drastically overhaul section 1332 waivers under the Affordable Care Act (ACA), including giving governors the ability to seek more flexibility without legislative approval, and to encourage people to sign up for plans that are not ACA-compliant.

A new study has indicated that long-term treatment with onabotulinumtoxin A is effective, safe, and well-tolerated in the patient population.

The breach comes as the Trump administration hopes to rely more heavily on professionals to assist consumers during open enrollment.

Certain dermatologic/mucosal conditions, use of corticosteroids, and intravenous antibiotics prior to chemotherapy may increase the risk of febrile neutropenia.

The Trump administration is considering narrowly defining gender as a biological, immutable condition determined by genitalia at birth; Medicare for All and single payer healthcare are suddenly popular, but what it means to the politicians embracing the terms are not exactly known; the Trump administration is expected to try to expand religious and moral exemptions for covering birth control in employer health insurance plans.

Accountable care organizations (ACOs) in the Medicare Shared Savings Program vary considerably in how they treat men with newly diagnosed prostate cancer, according to a study that assessed whether the level of engagement in ACOs by urologists could affect rates of treatment, overtreatment, and spending in prostate cancer care.

The EVI1 gene may be single-handedly at fault for acute myeloid leukemia, according to research published in Nature Communications.

A recent study looked to use real-world data to support the value of pathway regimens designed to create high-quality, affordable treatment in breast cancer care.

Neuromuscular blocking agents, or muscle relaxants, are often used in surgery to prevent muscles from moving when a patient is unconscious. A recent study found that the use of neuromuscular blockers during general anesthesia is associated with an increased risk of postoperative pulmonary complications.

The first trial to examine the impact of a self-management behavior-modification program combined with bronchodilator therapy and exercise training on exercise capacity and physical activity in patients with chronic obstructive pulmonary disease (COPD) showed positive results, according to a recently published study.

Women with HER2-positive early breast cancer with small tumors have similar disease-free survival and lower risk of cardiac toxicity with a 9-week course of adjuvant trastuzumab compared with those treated for 1 year, according to a study presented at the ESMO 2018 Annual Congress. A second study showed that a 6-month course of adjuvant trastuzumab was cost-effective compared to 12 months.

While mental health diagnosis can be associated with an increased use of emergency department (ED) visits, prior patient visit patterns were also associated with higher future ED use.

A review of migraine and cluster headache emphasizes how their shared pathophysiological pathways may be important for identifying future treatments.

Benzodiazepines are typically prescribed to treat chronic obstructive pulmonary disease (COPD) symptoms and are also typically prescribed for those with posttraumatic stress disorder (PTSD). However, a recent study found that long-term use of benzodiazepine medications in patients with both COPD and PTSD may be associated with a greater suicide risk.

A retrospective cohort study by compared different osteoporosis preventative-medications and found that selective estrogen receptor modulators (SERM) had better hip and major fracture risk reductions than alendronate, while strontium ranelate (SR) had poorer hip and major fracture risk reduction than alendronate.

Switchable chimeric antigen receptor (CAR) T cells with a switch directed towards human epidermal growth factor receptor 2 (HER2) in pancreatic ductal adenocarcinoma (PDAC) has similar efficacy as conventional HER2 CAR T cells while also having a greater control over treatment toxicities.

Researchers developed and validated a risk score to predict febrile neutropenia in cycles 2 to 6 of chemotherapy.

Health experts are questioning the practice of allowing private insurers to manage public Medicaid contracts; doctors and scientists are urging a halt to a taxpayer-funded, $63 million medical trial based in part on the work of prominent Harvard Medical School scientist Piero Anversa; a Michigan pharmacist who refused to refill a woman’s miscarriage medication because he claimed he was a “good Catholic male” is no longer with Meijer.