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“Our data suggest that people with central obesity, insulin resistance, and active psoriasis are the most at risk for liver fibrosis,” wrote the authors, and “if use of methotrexate is a risk factor, it is not the only risk factor and for most patients it is unlikely to be the most important risk factor.”

The clinical manifestations of symptoms experienced by children and adolescents with narcolepsy can differ from those seen in adults, presenting barriers to a timely diagnosis.

A screening test could be used in clinical trials on prevention of the disease.

As survival rates for malignant melanoma increase, so does the likelihood that some patients will develop second primary cancers.

The clinical features of systemic inflammation in chronic obstructive pulmonary disease (COPD) are well recognized, but little is understood about the molecular mechanisms underlying this inflammation.

Patients with monoclonal gammopathy of undetermined significance (MGUS), a precursor to multiple myeloma (MM), can progress from low- or intermediate-risk to MM in just 5 years, according to researchers who are now recommending all patients with MGUS undergo blood testing and risk assessment.

The authors said their study shows that implementing migraine guidelines into day-to-day clinical practice needs improvement.

The survey aimed to better understand the perceptions, experiences, and educational needs of patients who have nonmotor symptoms of Parkinson disease as well as their caregivers.

Providers are using outdated practices to connect with patients for their bills.

Obstructive sleep apnea, a catalyst for higher rates of depression, is a factor in the failure of major depressive disorder treatment, according to a June study published in The Journal of Psychiatric Research.

A recent review of biomarkers of subclinical atherosclerosis in patients with psoriatic arthritis (PsA) showed more severe atherosclerotic disease compared with patients who have only psoriasis.

Asthma adversely affects the everyday lives of many individuals regardless of long-term maintenance medication, according to a study evaluating the association of time spent at work and adverse asthma effects.

The study found that 24% of those who contacted a center specializing in rare kidney diseases would have gone undiagnosed if they had not reached out directly via the center's website.

People who have better cardiovascular health, as scored by the American Heart Association's Life's Simple 7, at age 50 have a lower risk of developing dementia over the next 25 years, according to a new study.

In the 5 years before being diagnosed, patients with multiple sclerosis (MS) were less likely to receive vaccinations than comparator groups, according to a new study from the Technical University of Munich and published in Neurology.

Mistrust in healthcare can have big repercussions and can perpetuate ongoing health disparities. Here are 5 things about medical mistrust.

This week, the top managed care stories included CMS giving chimeric antigen receptor T-cell payments a boost; a US task force announcing that those at risk for pancreatic cancer should be screened; FDA revealing Novartis withheld data about a high-cost gene therapy.

A new understanding of how poly (ADP ribose) polymerase (PARP) inhibitors work could expand the patient populations who are treated, according to a study. The researchers also identified a potential biomarker to indicate which patients would benefit the most.

Researchers found that they were able to use a small molecule called ZL0580 to modify bromodomain-containing protein 4 to suppress HIV.

The FDA ordered 4 companies to stop selling 44 of their flavored e-liquid and hookah tobacco products that lack the required approval for sale; CMS has yet to implement a 2014 law preventing unnecessary, expensive screening tests (magnetic resonance imaging, computed tomagraphy scans and other tests) that could harm patients and waste resources; Amarin, which is seeking FDA approval for an expansion of Vascepa labeling to include data that showed a 25% reduction in the risk of heart attacks and strokes, said the FDA has scheduled an advisory committee meeting for November 14.

Results of this study suggest dosing for vaccines should be adjusted based on age and gender of the patient.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

Since the first call to action was published in 2015, there have been 18 firearm-related mass murders with 4 or more deaths, killing 288 people and injuring 703 more.

Weeks after the first 2 anticancer biosimilars entered the US market, OneOncology announced that its partner practices have already started administering the drugs.

Artificial intelligence can be used to ameliorate reading time for digital breast tomosynthesis while maintaining or improving the accuracy of the reading, according to a new study.

Through the study, researchers identified a potential treatment target that could lead to alternatives for preventing the life-threatening condition.

The study's lead author said more work is needed to develop screening protocols for people who may face familial risk of a blood cancer.

On Wednesday, CVS announced strong second-quarter profits; DBV Technologies has submitted its Biologics License Application to the FDA for its treatment for peanut allergy; doctors, health organizations, and students are pushing for medical education to include climate change.

There is widespread anecdotal belief that caffeine can cause migraines or ease them once they’ve begun, although there is little scientific evidence to back that up. A new study released Thursday says that it’s the quantity that matters—having 3 or more caffeinated drinks a day is linked to a headache that day or the next.

In a long-awaited national coverage determination decision, CMS said Wednesday that it approved chimeric antigen receptor (CAR) T-cell therapies for Medicare beneficiaries nationwide.