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Researchers found the application of FOLFOXai, an artificial intelligence (AI)–based predictor of response to FOLFOX chemotherapy in metastatic colorectal cancer (mCRC), may lead to improved treatment outcomes for some patients with mCRC and other cancers.

Pfizer CEO shares his expectations for its coronavirus disease 2019 (COVID-19) vaccine approval; peer review results are in for AstraZeneca and Oxford University’s COVID-19 vaccine candidate; there are now competing legislative proposals on surprise medical billing protection.

New devices can help to manage sleep apneas, but underlying conditions must be treated, too, noted Krishna M. Sundar, MD, clinical professor, Pulmonary Division, Department of Medicine, medical director, Sleep-Wake Center, University of Utah.

The pandemic's effects on migraine need to be evaluated for the whole of 2020 and data from one specific time are not enough, said Faraidoon Haghdoost, MD, a general practitioner and PhD student at The George Institute for Global Health in Sydney, Australia.

A panel at the 2020 San Antonio Breast Cancer Symposium discussed 3 new drug approvals from the past year, highlighting changes in the treatment landscape across multiple breast cancer types.

Top reasons why patients with heart failure face a higher risk of hospitalization during times when fracking occurs include an increase in air pollution and stress pathways.

Rachel Jimenez, MD, radiation oncologist at Massachusetts General Hospital, outlines the prevalence of cardiac toxicity, as well as the short-term and long-term impacts.

Among women hospitalized with coronavirus disease 2019 (COVID-19), use of metformin—a type 2 diabetes (T2D) drug used to manage blood sugar levels—was associated with a 21.5% lower risk of death.

Inqovi is an orally administered, fixed-dose combination of the DNA hypomethylating agent, decitabine, and cedazuridine, an inhibitor of cytidine deaminase.

The American Society of Clinical Oncology calls on government bodies and the health care community to guide the cancer community’s post-pandemic recovery.

SEQUOIA arm D study results show better outcomes are possible for patients with 17p-deletion CLL, explained Ian Flinn, MD, PhD, director of lymphoma research at Sarah Cannon Research Institute.

An increase in primary rhegmatogenous retinal detachment incidence (RRD) may be associated with a simultaneous increase in myopia among citizens residing in the Netherlands, according to study results published in JAMA Ophthalmology.

With age comes a greater comorbidity burden, noted Milena Murray, PharmD, MSc, BCIDP, AAHIVP, associate professor at Midwestern University College of Pharmacy who practices at Northwestern Medicine's Infectious Disease Center in Chicago.

As more data have become available, we are seeing more and more patients receiving chimeric antigen receptor (CAR) T-cell therapy in the community setting, noted Karl Kilgore, PhD, senior research scientist at Avalere Health.

The United Kingdom administers the first doses of Pfizer's coronavirus disease 2019 (COVID-19) vaccine; an FDA review confirms the safety and efficacy of Pfizer's vaccine; Fauci advises holiday gatherings be limited to 10 or less people.

The effectiveness of telemedicine services among patients with neurological conditions was spotlighted amid the coronavirus disease 2019 (COVID-19) pandemic, particularly how telephone and video consultations have fared in temporarily replacing face-to-face consultations.

Updated guidelines help to address which patients are most appropriate for biologic therapy, noted Anne Reihman, MD, University of Colorado, Division of Pulmonary Sciences and Critical Care Medicine.

The presence of migraine is a significant risk factor for the development of subsequent peripheral artery occlusive disease, according to results of a retrospective cohort study published in the International Journal of Environmental Research and Public Health.

Data presented at the 62nd Annual ASH Meeting demonstrated the clinical utility of Adaptive Biotechnologies’ clonoSEQ next-generation sequencing to detect MRD in multiple myeloma patients.

During a session at the at the 18th annual World Congress Insulin Resistance, Diabetes & Cardiovascular Disease presented by the Metabolic Institute of America, experts outlined the benefits and limitations of pharmacological, surgical, and lifestyle interventions for pediatric patients with obesity.

Between the first introduction of population carrier screening in 2008 and its expansion to the full Israeli population in 2013, the mean rate of prenatal diagnoses per year was 4.66, and this rose to 7.75 between 2014 and 2017, a 66% increase.

With leading health experts warning of a grim few months ahead as the pandemic continues to rage, and as a vaccine launch grows more imminent, this 3-part series explores the impact of existing health disparities on COVID-19 and some potential solutions.

Coronavirus disease 2019 (COVID-19) vaccine doses to be administered this week in UK; President-elect Joe Biden nominates HHS secretary, CDC director; Biotechnology Innovation Organization sues to block new international drug pricing policy.

Twelve-month maintenance data from this study demonstrate the survival and response benefits associated with daratumumab, noted Mark Wildgust, PhD, vice president of Global Medical Affairs/Oncology at Janssen.

Zanubrutinib has a cleaner kinome than ibrutinib in that it hits fewer off-target kinases, said Ian Flinn, MD, PhD, director of lymphoma research at Sarah Cannon Research Institute.

At the National Alliance’s 2020 Annual Forum, a chief focus was spotlighting issues within the workplace exacerbated by the coronavirus disease 2019 pandemic such as mental health and disparities in availability of health care services.

Overall survival from early breast cancer has steadily been increasing; however, simultaneous increases in obesity and obesity-related comorbidities may have contributed to the survival disparity seen between these patient groups.

Researchers from the University of California San Francisco published their results in the Journal of Urology.

There have been exceptional results seen in CARTITUDE-1, stated Deepu Madduri, MD, assistant professor at the Icahn School of Medicine at Mount Sinai in New York City and associate director of its cellular therapy program.

Research presented at this year’s annual meeting of the Radiological Society of North America shows the possible impact of food or housing insecurity on follow-up appointments for breast cancer.