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Older patients are at greater risk of death in the earliest stages of dialysis, while females possibly are at a higher risk than men, a review of studies found.

Changes in temperature and atmospheric pressure were found to be associated with higher rates of medical care utilization for patients with chronic obstructive pulmonary disease (COPD) and asthma.

Visual dysfunction among patients with Parkinson disease was associated with worse cognitive performance after 18 months and a higher risk of developing mild cognitive impairment compared with those with normal vision.

Patients with chronic kidney disease (CKD) healthy enough not to have seen a specialist have higher hospitalization rates than the general population, according to a recent study.

The results from an analysis of patients from 12 rheumatology centers treated with secukinumab for psoriatic arthritis were in line with earlier pivotal trials, the researchers said.

The most recent Morbidity and Mortality Weekly Report from the CDC shows there is a great unmet need for earlier intervention for and treatment of HIV among Black Americans living in rural areas.

The current guidance emphasizes that the mRNA-based Pfizer/BioNTech and Moderna vaccines are safe for people with multiple sclerosis (MS) taking disease modifying therapies (DMTs).

As Medicaid is a federated program between states and the federal government, it has historically been difficult for innovation to spread state to state, hindering any comparison of quality metrics.

Gabapentin and baclofen can improve chronic refractory cough caused by gastroesophageal reflux disease, but efficacy is limited and further study needed.

An anxiety screening tool should be included during initial assessments of migraineurs by medical practitioners, according to the authors of a systematic review published in Frontiers in Neurology.

Older adults who reported getting 5 hours or less of sleep per night exhibited a more than 2-fold increased risk of dementia than those who reported 7 to 8 hours of sleep, with sleep disturbance and deficiency additionally linked with overall risk of death.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

The Pfizer/BioNTech coronavirus disease 2019 vaccine can be stored at higher temperatures; the Biden administration pledges $4 billion over 2 years to Gavi, the Vaccine Alliance; Medicare payments will soon decrease for hundreds of hospitals.

This week, the top managed care news included Entresto winning the first FDA nod in a hard-to-treat type of heart failure; President Joe Biden nominates a new CMS administrator; experts discuss the potential for Biden health reforms.

Hypertension, anemia, and infection were the most common adverse events associated with mantle cell lymphoma (MCL), while hepatotoxicity, stroke, and renal failure were the costliest per patient.

An article by Willis Towers Watson discusses how employers are supporting their respective workforce amid the pandemic, with education of approved vaccines and effective communication channels with state and local health departments referenced as key actions to be taken at this time.

The SURPASS program, which consists in part of SURPASS-3 and SURPASS-5, is testing the efficacy and safety of tirzepatide, a novel investigational once-weekly dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist.

The coronavirus disease 2019 (COVID-19) pandemic has led to sharp declines in US life expectancy; a new CMS administrator nominee is selected; Biden administration announces funds to combat virus variants.

During a 2021 AcademyHealth National Health Policy Conference session, members of The Commonwealth Fund Task Force on Payment and Delivery System Reform discussed policy recommendations aimed at preparing the United States for future pandemics and addressing care inequities brought to light by the coronavirus disease 2019 crisis.

The abnormal clumping and accumulation of alpha synuclein has been shown to cause and spread dysfunction in cells, leading some to characterize Parkinson disease by proteinopathy or as a protein disease.

The cyclin-dependent kinase 4/6 inhibitor trilaciclib (Cosela) is the first in its class to receive FDA approval as a protective agent against bone marrow loss from treatment for small cell lung cancer (SCLC).

In a panel at the 2021 AcademyHealth National Health Policy Conference, representatives from 3 community health plans across the United States discussed how payers are driving telehealth access and utilization in the wake of the coronavirus disease 2019 pandemic.

Living far from a hospital did not increase risk of in-hospital mortality, according to a recent study among veteran populations with chronic obstructive pulmonary disease (COPD).

Compared with being offered standard testing services, offers of initial and repeat self-testing led to a 3.5-fold greater uptake of testing for HIV among transgender individuals in a new study out of England and Wales.

Novartis is teaming up with the Gates Foundation to develop a gene therapy for sickle cell disease; the World Health Organization reports a drop in global cases of coronavirus disease 2019 (COVID-19); storms hinder vaccine rollout across the United States.

On this episode of Managed Care Cast, we highlight a new feature on AJMC.com, the website of The American Journal of Managed Care®, called Clinical Spotlight, where our editors provide a series of interviews with leading experts in certain specialties.

Novartis' drug, which combines sacubitril and valsartan, is the first to directly treat patients with heart failure with preserved ejection fraction.

The new indication for osimertinib (Tagrisso) marks the first FDA approval of an adjuvant treatment for non–small cell lung cancer (NSCLC) with EGFR exon 19 deletions or exon 21 L858R mutations.

Based on positive phase 3 results in adults with idiopathic hypersomnia, Jazz Pharmaceuticals submitted a supplemental new drug application (NDA) to the FDA for Xywav (calcium, magnesium, potassium, and sodium oxybates) oral solution.

A recent study investigated what makes some non-small cell lung cancer patients with a type of human leukocyte antigen (HLA) called B44 are more likely than others to respond to immunotherapy.