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The 5-year update could help solidify the role of sodium glucose co-transporter 2 (SGLT2) inhibitors in treating heart failure, years after the first evidence of their effectiveness emerged.

A recent study found that older age, male gender, lack of surgical resection or chemotherapy, and late-stage disease may be poor prognostic factors for diffuse large B-cell lymphoma (DLBCL) of the urinary tract.

Although there is an established link between type 2 myocardial infarction (T2MI) and elevated rates of cardiovascular events, less is known about the connection between T2MI and heart failure—which this new study investigated.

Researchers said the blood test offers an earlier warning of hepatocellular carcinoma than current methods.

Foundation Medicine and Epic struck a deal to integrate comprehensive genomic profiling within Epic's electronic health records (EHRs), allowing for providers to order and review genomic profiling tests, leading to more streamlined clinical decision making.

Researchers offer recommendations for addressing polypharmacy and potentially inappropriate medication (PIM) use among older patients with cancer.

Patients with psoriasis who received biologic treatments were at significantly lower risk of developing psoriatic arthritis, with women representing a potentially at-risk group.

The United States Preventive Services Task Force (USPSTF) lowered its recommended screening age for type 2 diabetes and prediabetes from 40 to 35 years among overweight and obese individuals.

Delta Air Lines raises health insurance premiums for employees not vaccinated against COVID-19; the Pentagon requires all active-duty service members to receive a COVID-19 vaccine; 2 mental health giants merge into 1 company worth $3 billion.

An overview of the latest news in Parkinson disease reported across clinical research.

The genomic alterations in prostate cancer were detected from tissue biopsies of primary tumors and metastatic sites as well as from liquid biopsies of circulating tumor DNA, the latter of which has emerged as an increasingly popular method for genomic analyses across various types of cancer.

There are incredible data for sodium-glucose co-transporter 2 (SGLT2) inhibitors, and this is a great class of medicines that is vastly underutilized, stated Deepak L. Bhatt, MD, MPH, executive director of interventional cardiovascular programs at Brigham and Women’s Hospital Heart & Vascular Center and professor of medicine at Harvard Medical School.

Approximately 1 in 6 healthy individuals who underwent proactive genetic screening had genetic variants linked to increased risk for developing medically actionable disorders, including certain cancers and cardiovascular disorders.

Autophagy inhibition could help patients who develop resistance to BRAF inhibitors, but a new review shows important questions remain.

The lack of approved treatments for heart failure with preserved ejection fraction has represented a significant unmet need for a condition that affects 50% of patients with heart failure, including large subgroups, such as older women.

Randomized controlled trials on asthma hospitalization prevention are limited, but patient and caregiver education should be a top priority, investigators said.

Post hoc analyses revealed patients with episodic migraine (EM) who take erenumab experience less intense headache pain on average.

Delta variant lowers COVID-19 vaccine effectiveness to 66%; Johnson & Johnson reports booster shot results; cancer center reports mask, vaccine preferences of patients.

Elderly patients who underwent surgery for glaucoma had a greater risk of all-cause and cause-specific mortality than those who did not have surgery, including greater risk of cancer and neurologic cause–related mortality.

Ann Goebel-Fabbri, PhD, a clinical psychologist in Boston, Massachusettes, dispels common misconceptions involving eating disorders among patients with type 1 diabetes.

The European-based survey collected information from over 900 patients and caregivers from 25 countries; the responses show a need for both local and national governments to scale up their services for patients with rare metabolic diseases, which also have a positive spillover effects for caregivers.

Survey responses from patients with advanced cancer revealed that there were gaps in knowledge across various aspects of immunotherapy treatment, including about side effects and curative potential.

There will be new ESC heart failure guidelines and presentation of data from EMPEROR-Preserved and EMPEROR-Pooled, noted Rudolf de Boer, MD, PhD, of University Medical Center Groningen, the Netherlands.

A new report suggests corticosteroids likely are not a panacea for ocular surface disease, a potential adverse effect of trabeculectomy.

Because cardiac fibrosis can develop under very diverse etiological circumstances, it is extremely heterogeneous.

Patients with axial spondyloarthritis waited the longest, according to new research.

Patients with comorbid Alzheimer disease and insomnia were found to be more likely to report claims of higher cost health care services such as inpatient hospitalization and emergency care, along with significantly greater mean total annual health care costs than those without insomnia.

Experts update timetable of COVID-19 vaccine trials for children under 12; vaccine mandates happen nationwide in wake of the Pfizer/BioNTech approval; sedentary behavior is associated with 7-fold increased risk of stroke.

On this episode of Managed Care Cast, Laalitha Surapaneni, MD, MPH, an assistant professor of medicine at the University of Minnesota, describes her work in bringing awareness to the health impacts of climate change.

In comparison with reference rituximab (Rituxan), the use of rituximab biosimilars in combination therapy produced similar 3-year overall survival among patients with large-B-cell lymphoma (DLBCL), investigators concluded.