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The share of patients meeting the definition of polypharmacy for the condition of overactive bladder declined from 2006 to 2017, but the phenomenon was still prevalent in women and patients in nursing homes, according to a recent study.

Adults with atopic dermatitis were shown to be at lower risk of developing asthma if they were vaccinated against influenza, particularly those who adhered to yearly shots.

Robert A. Gabbay, MD, PhD, chief scientific and medical officer at the American Diabetes Association, discusses COVID-19 vaccinations among people with diabetes as they have been disproportionally affected by the pandemic.

Tiffany Powell-Wiley, MD, MPH, a Stadtman investigator and chief of the Social Determinants of Obesity and Cardiovascular Risk Laboratory at the National Heart, Lung, and Blood Institute, with a joint appointment at the National Institute on Minority Health and Health Disparities, discusses ongoing trials and the American Heart Association’s Scientific Statement on social determinants of obesity and cardiovascular disease.

The Supreme Court of Oklahoma ruled that Johnson & Johnson cannot be held liable for the state’s opioid crisis; a trial found the psychedelic drug psilocybin may be a highly efficacious therapy for treatment-resistant depression; people who went to bed at midnight or later had a 25% greater risk of cardiovascular disease.

An evaluation of data from the Global Burden of Disease found that nonalcoholic fatty liver disease (NAFLD) is a main driver of chronic liver disease and has increased among adolescents and young adults.

Outcomes of in-hospital mortality, 7-day mortality, and emergency department length of stay were investigated among a cohort of patients with acute heart failure and hypercapnia, or excessive levels of CO2 in the blood.

The report suggests childcare concerns could be a significant factor keeping Black women from attending weekly workshops.

If FDA approved for children, secukinumab (Cosentyx) will be the first biologic treatment for children in the US living with enthesitis-related arthritis.

An overview of activities at the FDA to promote the use of biosimilars was presented by Jacqueline Corrigan-Curay, JD, MD, principal deputy center director for the Center for Drug Evaluation and Research (CDER) at the FDA.

Findings of a real-world, single-center study indicated that apremilast was effective and safe long-term in the treatment of moderate-to-severe plaque psoriasis.

This cohort study of women living with HIV, pregnant and not pregnant, investigated outcomes related to engagement in HIV care following a live birth.

The analysis showed biomarkers that persisted despite the presence or absence of type-2 inflammation.

On this episode of Managed Care Cast, we speak with Abi Sundaramoorthy, MD, MBA, executive vice president of clinical enterprise at Somatus, on fragmented care in chronic kidney disease, its disproportionate impact on minority communities, and the potential of value-based arrangements to address disparities and promote preventive, effective care.

The parameter could potentially help clinicians zero in on the cause of left ventricular hypertrophy.

Pfizer and BioNTech expect to seek emergency use authorization for their COVID-19 booster vaccine in all adults 18 years and older; the Biden administration urges appeals court to not block employer vaccine mandate; nearly 8 in 10 Americans believe or are unsure of false COVID-19 information.

The American Society of Ophthalmic Plastic & Reconstructive Surgery 2021 Fall Scientific Symposium will feature presentations on oculofacial surgery innovations, social justice and diversity, and more.

Jonathan Silverberg, MD, PhD, MPH, associate professor of dermatology, director of clinical research and patch testing, George Washington University School of Medicine and Health Sciences, discusses the involvement of the JAK/STAT pathway in the pathogenesis of atopic dermatitis.

Joseph Mikhael, MD, of the Translational Genomics Research Institute in Phoenix, Arizona, an affiliate of City of Hope, spoke with The American Journal of Managed Care® about the increased use of triplet therapy to treat this disease.

Most adverse events in trials of adenosine triphosphate (ATP) blockers for chronic cough are related to taste, which may inadvertently cause the studies to become unblinded to patients, and a way of measuring this to know the extent of the problem is needed, said Ron Eccles, BSc, PhD, DSc, emeritus professor at Cardiff University.

Patients with lupus nephritis (LN) were found to have as much as twice the inpatient hospitalizations of patients with systemic lupus erythematosus without LN.

Researchers outlined the need to combat underrepresentation of racial minorities in pulmonary arterial hypertension (PAH) registries and trials.

Research presented at Kidney Week 2021 suggests sodium-glucose co-transporter 2 inhibitors may show beneficial cardiovascular (CV) and kidney effects among patients with type 1 diabetes.

Hospitalization for an acute kidney injury (AKI) event was identified as a risk factor for several adverse events after hospital discharge, including hospital readmission and mortality, according to findings presented at Kidney Week 2021.

Findings of an abstract presented at CHEST 2021 indicated that antidepressant use was associated with increased REM sleep latency and a complete lack of REM sleep, which may contribute to the poorer quality-of-life scores observed in these patients.

More research is needed to better understand the potential therapeutic benefits of ketamine among migraineurs, concluded authors of a systematic review and meta-analysis.

Results of a cross-sectional study detail characteristics among women with polycystic ovary syndrome (PCOS) who develop type 2 diabetes.

The United States lifts travel restrictions for numerous countries, requiring proof of vaccination and in some cases negative COVID-19 tests; discrimination of any kind was associated with greater risk of mental health problems in young people; a controversial Alzheimer disease drug faces several uptake issues.

Richard Wasserman, MD, PhD, an allergist and immunologist with Allergy Partners of North Texas, an early adopter of food allergy oral immunotherapy (OIT), discusses how attitudes have changed around the practice.

To avoid bankrupting health care, providers must carefully consider how they use biologics in patients with severe asthma, according to a presenter at the American College of Allergy, Asthma & Immunology Annual Scientific Meeting.