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Improved management of sickle cell disease has vastly improved life expectancy and reduced morbidity for affected patients, but the disease itself and its treatments carry fertility risks that many young patients and their caregivers are unaware of.

In an effort to bolster development of treatments for rare diseases, the FDA announced the creation of the new Accelerating Rare disease Cures (ARC) program.

Hidradenitis suppurativa (HS) was associated with a variety of comorbid conditions, from psoriasis to hypertension.

A cohort study found that patients receiving dialysis had decreased mortality rates over time from myocardial infarction (MI), stroke, and pulmonary embolism (PE) compared with the general population.

A Senate vote to protect abortion access nationwide failed; drug overdoses hit a record high in the United States during 2021; the European Union lifted its travel mask recommendation.

Biosimilar adoption can be accelerated or stymied depending on actions taken by the managed care space, explained Sonia Oskouei, PharmD, vice president, biosimilars, Cardinal Health, during a session at Asembia’s Specialty Pharmacy Summit.

Patients with comorbid chronic rhinosinusitis (CRS) with nasal polyps and severe asthma reported significant improvement in their sense of smell when treated with the biologics omalizumab, mepolizumab, reslizumab, or benralizumab, with no significant differences observed between the treatment groups.

A study conducted in China found that long-term exposure to ambient particulate matter increased the risk of chronic kidney disease (CKD).

Debra Patt, MD, PhD, MBA, executive vice president of Texas Oncology, discusses how community oncology practices have heightened their outreach efforts to entice patients back in for cancer screenings and the importance of thinking outside the box to overcome staffing shortages in the oncology space.

Oral care decreased both the number of intensive care unit (ICU) patients and the length of stay, as well as the amount of time of mechanical ventilation.

David Skomo, and Nick Page, PharmD, of WellDyne offered their perspectives on recent developments in precision medicine at the 2022 Asembia Specialty Pharmacy Summit.

This new study among a patient population living with type 1 diabetes compared their outcomes according to their type of insulin pump therapy: sensor-augmented pump, predictive low-glucose suspend, and hybrid closed-loop (HCL).

A randomized, double-blind study found that there was no difference in the recording quality of a home sleep apnea test between patients given in-person instruction vs video instruction, which is an important step in telemedicine diagnosis of obstructive sleep apnea (OSA).

Very elderly patients with acute myeloid leukemia have historically been limited to less intensive, less effective treatment regimens. A recent series of cases suggests age alone should not be a limiting factor for effective treatment.

Bimekizumab demonstrated a favorable long-term safety profile for the treatment of moderate to severe psoriasis, aside from an increased incidence of mild to moderate oral candidiasis that was also observed with short-term exposure.

Cholangiocarcinoma (CCA), or bile duct cancer, is classified by its location, with intrahepatic CCA (iCCA) referring to those cancers that form in bile ducts within the liver.

Firearm homicide jumped by nearly 35% between 2019 and 2020; nearly 400 million COVID-19 vaccines were destroyed at Emergent BioSolutions’s Baltimore facility; a study found high blood pressure in younger people may be associated with negative cognitive effects later in life.

A study of hospitals and long-term care facilities in Louisville, Kentucky, found low rates of Clostridioides difficile testing in patients with new-onset diarrhea who are frequently infected.

On this episode of Managed Care Cast, we speak with Joanne Armstrong, MD, MPH, vice president and chief medical officer for Women’s Health and Genomics at CVS Health, on the distinct pathophysiology of cardiovascular disease in women and how her own health experiences have influenced her perspective on cardiovascular disease management.

Dermatology specialists were cited by diverse caregivers of children with atopic dermatitis (AD) to provide enhanced care delivery and improved AD disease control compared with primary care providers.

Male sex, older age, lower socioeconomic status, higher comorbidity score, and having an older or male rheumatologist were associated with the reduced likelihood of continuing with rheumatoid arthritis (RA) treatment.

The US Preventive Services Task Force (USPSTF) found after a reaffirmation process that there was no net benefit to screening asymptomatic adults for chronic obstructive pulmonary disease (COPD).

COVID-19–related hospitalizations are up 17% week over week; an estimated 5 to 14 million Americans could lose their Medicaid coverage this year or next year; the CDC is investigating unexplained cases of severe hepatitis in children.

In a session at the 2022 Asembia Specialty Pharmacy Summit, Jayne Hornung, chief clinical officer at Managed Markets Insights & Technology (MMIT), outlined factors driving payer hesitation when it comes to covering prescription digital therapeutics.

Marking Mental Health Awareness month, stakeholders involved in the delivery of behavioral health care services discuss current efforts underway—spearheaded by the novel 988 emergency hotline—to address the growing mental health crisis.

The study of constructed αROR1‐CAR T cells showed an increase of PD-L1 expression when exposed to elevated pressure, driving resistance to CAR T cell-mediated cytotoxicity. However, the findings also suggest that adding PD-1/PD-L1 inhibitors to CAR T-cell therapy could help address this.

More experienced dermatopathologists were less likely to see overdiagnosis as a significant public health problem, a new survey showed.

Black, Asian, and Hispanic adults in the United States were found to have an increased risk for developing diabetes at lower weights and younger ages compared with White Americans, suggesting that screening recommendations for the disease should be altered to reflect this difference.

A recent study sought to address what is known about proton pump inhibitors (PPIs) as a therapy for eosinophilic esophagitis and long-term outcomes in patients who respond to them as a way to guide treatment decisions.

The study highlights differences between patients with systemic lupus erythematosus (SLE) and healthy controls, potentially shedding light on the disease’s underlying mechanisms.