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A significant portion of patients who receive chimeric antigen receptor (CAR) T-cell therapy experience immune effector cell–associated neurotoxicity syndrome, and this recent study suggests neurofilament light chain protein levels may hold promise as a biomarker to identify at-risk patients.

Under a new contract with AmerisourceBergen Corp, HHS will expand access to monkeypox vaccines and treatments; as President Jow Biden encouraged Americans to receive their COVID-19 boosters this fall, the White House signaled toward annual COVID-19 boosters; Juul has reached a settlement with 37 states and Puerto Rico regarding the company’s marketing to teens.

Night sweats were independently associated with a higher hypoxemia burden in patients diagnosed with obstructive sleep apnea (OSA).

This study investigated long-term mortality outcomes following transcatheter aortic valve replacement (TAVR) among patients with a left ventricular ejection fraction (LVEF) below 50% and comorbid severe aortic stenosis.

Significant worsening of physical and mental symptoms of Parkinson disease was shown in a meta-analysis of diverse patients during the COVID-19 pandemic, with those of lower-income countries shown to be exceptionally vulnerable.

A prospective cohort study found that women who replaced processed red meat with fatty fish, unprocessed red meat, or vegetables had reduced risks of hypertension and diabetes.

Post-menopausal women who had dynapenic-abdominal obesity, determined by hand-grip strength and waist circumference, had a higher risk of chronic kidney disease (CKD) compared with controls.

An estimated 1 in 4 patients treated with durvalumab and chemotherapy (gemcitabine plus cisplatin) was alive at 2 years compared with 1 in 10 treated with chemotherapy alone, with these results contributing to the FDA's approval of the first immunotherapy to treat these cancers.

The case emphasizes the importance for clinician awareness of the potential for rare immune-mediated disorders, including acquired hemophilia A (AHA), following allogeneic hematopoietic stem cell transplantation (HSCT).

A new therapeutic paradigm has heightened the need for meaningful measures of assessing patients.

CVS announces its plan to buy Signify Health for $8 billion; government budgets and low reimbursement could limit the ability for new moms to stay on Medicaid for a year after childbirth; the long-lasting symptoms of COVID-19 could be keeping millions of people out of the workforce.

A new study finds anxiety and depression are more common in people with systemic lupus erythematosus (SLE) if they also have nephritis.

The increase in the incidence of hepatocellular carcinoma in Louisiana was nearly double that of the United States as a whole between 2005 and 2015.

The management of myeloproliferative neoplasms (MPNs) in adolescent and young adult (AYA) patients is currently similar to that of older patients. However, comprehensive research is needed to form guidelines for this younger population.

The multidisciplinary home care program aims to improve health outcomes and functioning while reducing health care use and preventing long-term nursing home placement.

A review of 6 studies on treatment options for hepatic encephalopathy found that many require further research before they can be recommended.

Inactive occupational status and low educational level were associated with pain, late disease onset, and greater number of affected areas in patients with hidradenitis suppurativa.

A digital pet app used as a prescription digital therapeutic (PDT) to encourage children to complete prescribed therapies received high engagement and function scores from children living with neurodevelopmental disabilities.

The ALLIANCE trial is investigating the responses of treatment-naïve persons living with comorbid HIV (PLWH)/hepatitis B virus to a triplet regimen of bictegravir/emtricitabine/tenofovir alafenamide vs dolutegravir plus emtricitabine/tenofovir disoproxil fumarate.

A recent review suggests point-of-care ultrasound can help home hospital care providers assess, diagnose, and monitor a range of conditions with relatively little additional training.

Older adults who reported longer total sleep time, lower rapid eye movement (REM) sleep percentage, and higher minimum oxygen saturations during REM sleep had an increased risk of developing Parkinson disease (PD).

Machine learning models collected using a crowdsourcing approach that provide feasible, quick, and accurate methods to quantify joint damage in rheumatoid arthritis (RA) could potentially be incorporated into electronic health records.

The researchers compiled data from studies of lirentelimab, mepolizumab, reslizumab, and benralizumab, highlighting the difficulties in finding an effective approach with eosinophil-targeted treatments for eosinophilic esophagitis (EoE).

Groups at risk for underrecognition and undertreatment of depression had improved rates of depression screening after implementing routine adult depressions screening in primary care.

The review of 5 phase 3 randomized controlled trials found that overall, the combination treatments improved survival outcomes while eliciting more, but manageable, side effects.

A narrative review found that some risk factors may be associated with cognitive impairment in patients with type 1 diabetes.

As the feasibility of phase 1 clinical trials for prenatal spinal muscular atrophy (SMA) therapies is explored, patient and parent input on prenatal testing and possibly treatment is a valuable tool for guiding research discussions.

Nurse-led education is an essential aspect of care for patients with bleeding disorders, but there is currently a lack of research on specific strategies to improve patient self-management through education.

A new analysis found only 1 in 10 studies of inequities in liver cancer had a European focus or origin.

New studies have linked a diet of ultra-processed food to a higher risk of colorectal cancer and to an overall risk of mortality; the CDC endorsed the updated booster shots from Moderna and Pfizer-BioNTech for use against the omicron variant; South Carolina Department of Corrections and Pear Therapeutics are teaming up to support inmates recovering from substance use disorders.