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Baxdrostat is a highly selective aldosterone synthase inhibitor; phase 1 studies showed that the therapy caused a sustained, dose-dependent reduction in plasma aldosterone by more than 70% without reducing cortisol.

This new study evaluated the potential impact of unmet social needs on risk of severe asthma in children.

Pegcetacoplan was approved by the FDA to treat geographic atrophy (GA), providing a treatment option for patients who previously had none, explained Eleonora Lad, MD, PhD, associate professor of ophthalmology, Duke University.

The researchers used Paraphase on more than 400 samples of spinal muscular atrophy (SMA) comprising 5 ethnicities.

The study also showed, despite an existing association between discrimination based on sexual orientation and HIV pre-exposure prophylaxis (PrEP) use, increased resilience reduced the effects of such discrimination on PrEP use.

The risk of death among people with primary myelofibrosis (PMF) dropped by 53% after ruxolitinib’s introduction, the study found, although the data also suggested only 8.5% of patients were prescribed the drug.

A roundup of the latest biosimilar news from The Center for Biosimilars®.

Potential disparities in care highlight the great need for tailored cardiovascular health (CVH) interventions among bisexual female individuals, according to a recent study.

Eric Rackow, MD, cofounder and executive chairman of eFamilyCare, discusses the importance of virtual support for family caregivers.

Results from the CLEAR Outcomes trial were presented today at the 72nd American College of Cardiology (ACC) Scientific Session Together With the World Congress of Cardiology. Plans for a broader label are in the works.

Children with acute lymphoblastic leukemia living in US-Mexico border regions had worse 5-year survival rates compared with children living in other parts of Texas, a recent study found.

Adherence to annual lung cancer screening was only 22.3% among more than 1 million patients who underwent baseline screening between 2015 and 2019, a study published in the journal CHEST found.

A group of dermatologists and dermatology students studied why atopic dermatitis may be related to certain cardiovascular diseases, neuropsychiatric diseases, autoimmune diseases, and obesity.

Researchers of the multicenter study looked at the effect of nusinersen among 48 patients with spinal muscular atrophy (SMA) from 2 Italian hospitals, finding more active immune systems among the patients with SMA1, the most severe form of the disorder.

Incidence of medication problems and their harm potential following hospital discharge among pediatric patients with epilepsy were not significantly different for individuals who received discharge medication education and those who did not.

Models containing a national database of demographic and reproductive data predict the probability of a live birth success after in vitro fertilization (IVF).

Seeking to speed up the execution of evidence-based care practices, the Patient-Centered Outcomes Research Institute (PCORI) announced the 42 health systems across the country who will join a 5-year program to build capacity and implementation to improve health care outcomes.

Kevan Herold, MD, professor of immunobiology and medicine at Yale School of Medicine, talks about some insurers' requirement for patients to have a first-degree relative with type 1 diabetes to qualify for coverage of teplizumab.

Medicaid expansion deal proposed in North Carolina; FDA gains new leverage over quick drug approvals; Walgreens announces it will not dispense abortion pills in several states where it’s legal.

Coverage of our peer-reviewed research and news reporting in the health care and mainstream press.

Incidences of certain second primary malignancies were associated with increased overall survival among patients with multiple myeloma in a retrospective analysis of real-world data.

The 2 therapies, a 1-food and a 6-food elimination diet both used for eosinophilic esophagitis (EoE), were compared for outcomes after 6 weeks.

The 3 companies announced a partnership to provide free, same-day prescription delivery of HIV pre-exposure prophylaxis (PrEP) and antiretroviral medications.

Joneigh Khaldun, MD, MPH, FACEP, vice president and chief health equity officer for CVS Health, speaks on the launch of her organization’s Community Equity Alliance that aims to address structural barriers to equitable care in underserved communities through partnerships with local academic and health care institutions.

Rates of active surveillance for low-risk prostate cancer have improved nationally but vary locally and remain subpar overall, according to findings from a study published in JAMA Network Open.

Lee Greenberger, PhD, chief scientific officer of the Leukemia and Lymphoma Society, discusses common questions that patients with leukemia and lymphoma ask about COVID-19 and vaccination.

Edward W. Boyer, MD, PhD, medical toxicologist, The Ohio State University, discusses respiratory health risks associated with chemical exposure after the train derailment in East Palestine, Ohio.

A recent review found that the performance of the Amsler grid test was not at a level that was recommended for detecting early or dry age-related macular degeneration (AMD).

The European Medicines Agency’s Committee for Medicinal Products for Human Use has recommended the approval of cemiplimab-rwlc in combination with platinum-based chemotherapy as frontline treatment for adult patients with advanced non–small-cell lung cancer with PD-L1 expression of 1% or higher.

Manmeet Ahluwalia, MD, MBA, Miami Cancer Institute, discussed efforts being taken by his organization’s Center for Equity in Cancer Care & Research to address disparities in clinical trial enrollment of minority patients in the United States.