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A new study published Monday by scientists at the University of Massachusetts Medical School (UMMS) in Boston reports findings on a gene that is responsible for creating a protein that may help melanoma to grow and metastasize.

A systematic review of the FDA’s Adverse Event Reporting System (FAERS) found elevated reporting for both tofacitinib (Xeljanz) and ruxolitinib (Jakafi) for thromboembolic adverse events (AEs), suggesting the possibility of a class-wide issue with Janus kinase (JAK) inhibitors.

Semaglutide, Novo Nordisk’s once-weekly glucagon-like peptide-1 (GLP-1) receptor agonist for type 2 diabetes (T2D), received FDA approval Tuesday, after beating its rival in a head-to-head trial and coming to the approval process with proof of cardiovascular benefits already in hand.

Health information brand Healthline launched its “State of…” series with its “State of Cancer” study, analyzing how digital information influences patient treatment decisions and recognizing generational differences.

Senator Susan Collins, R-Maine, makes her tax bill vote contingent on more Obamacare funding; some states are setting up programs to recycle leftover drugs; and pregnant women deal with medication uncertainty.

Abdominal aortic aneurysm is a cardiovascular disease for which 45,000 operations are performed yearly in the United States, but a new study found that targeting lipids may improve long-term outcomes.

The FDA approved an injectable form of the drug buprenorphine for the treatment of moderate-to-severe opioid use disorder.

Some of the data associated with food allergy claims are not what one would expect.

The FDA has approved Foundation Medicine's FoundationOne CDx, the first-of-a-kind comprehensive companion diagnostic test for solid tumors. The test looks for hundreds of cancer genes, providing healthcare professionals with a more complete picture of what's causing tumor growth and guidance for treatment decisions.

A study published Thursday in JAMA Oncology found that improvements in survival among California cancer patients were almost exclusively limited to patients with private or Medicare insurance.

Mortality rates from opioid-driven hospitalizations in the United States quadrupled over 2 decades, especially among older, white, low-income populations, according to a study published in Health Affairs. The analysis showed that people enrolled in Medicare, and not those in Medicaid, accounted for the fastest-growing share of opioid and heroin poisoning.

A study of patients with severe chronic obstructive pulmonary disease (COPD) in Poland, The Republic of Korea, and the United States identified substantial differences in respiratory symptoms and other respiratory illnesses.

Sanofi’s newest insulin met its primary objective in a large head-to-head trial that compared it with its chief competitor.

The National Cancer Institute (NCI) is sponsoring an ongoing clinical trial that evaluates pembrolizumab in people with HIV who have relapsed or refractory cancer and are also taking antiretroviral therapy. People with HIV are often excluded from participating in clinical trials of new cancer treatments because of concerns that treatments may be unsafe for them.

Researchers at Duke University found there is substantial room for improvement in providing consumers with ready access to healthcare prices online.

A woman gives birth after receivng a uterine transplant for the first time in the US; a once-monthly treatment for patients with poioid addiction gains FDA approval; and LA public health officials launch an initiative to reduce the annual number HIV infections.

Republican leaders begin work Monday reconciling the differences in the Senate and House tax legislation, hoping to send a final bill to President Trump before Christmas. Senate Republicans passed the bill by 51-49 just before 2 am on Saturday.

CVS Health has proposed purchasing health insurer Aetna in a $69 billion deal that could disrupt the pharmacy benefit management business and "remake the consumer healthcare experience," according to CVS Health's president and CEO.

Federally qualified health centers (FQHCs) saw the benefit of funding from an American Cancer Society (ACS) program aimed at strengthening colorectal cancer screening rates over a 3-year period.

Researchers find brake mechanism that prevents an essential shell from forming on virus that causes AIDS.

CMS is focusing on patient empowerment and unburdening physicians, said CMS Administrator Seema Verma during her keynote speech at the Office of the National Coordinator for Health Information Technology’s Annual Meeting.

Trastuzumab-dkst is the first biosimilar approved in the US for treating breast cancer or stomach cancer and the second biosimilar approved in the US for the treatment of cancer.

The FDA update was based on results of the FOURIER trial, which showed the drug reduced the risk of heart attacks, strokes, and revascularizations in high-risk patients.

Countries in Southern and Eastern Africa have the highest prevalence of HIV worldwide. The Joint United Nations Program on HIV/AIDS strategy to end AIDS by 2030 has been dedicated to preventing HIV through voluntary medical male circumcision in Southern and Eastern African countries with HIV epidemics and low male circumcision prevalence.

A newly published retrospective study in The Annals of Thoracic Surgery found that lobectomy improved survival in patients with early-stage lung cancer compared with SBRT.

Panelists at the Office of the National Coordinator for Health Information Technology (IT)’s Annual Meeting discussed their perspectives on health IT innovation and expectations for 2018.

With the increasing emergence of less expensive biologic alternatives, some health systems are making the switch. For a large healthcare system, the arrival of a cheaper alternative to filgrastim prompted the conversion to using tbo-filgrastim as the preferrred granulocyte-colony stimulating factor. The results were shared in a study published by the Journal of Managed Care & Specialty Pharmacy.

This week, the top managed care news included a new proposal from CMS that insurers warn will cause confusion; a new review examines the prevalence and cost of chronic conditions in Medicaid; and a study finds 42% of all new US cancer cases in 2014 were due to potentially modifiable exposures.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

A growing number of clinicians specializing in nursing home care indicates the beginning of a new trend in healthcare, but the impact of these new specialists on outcomes remains unclear.