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The American Hospital Association will refile its 340B lawsuit against HHS after an appeals court ruled the lawsuit was premature; therapies approved by the FDA with breakthrough designation often lack strong medical evidence; a study has suggested that frequent use of digital media may increase the odds of adolescents developing symptoms of attention-deficit/hyperactivity disorder (ADHD).

Recent study results reveal the importance of the role of astrocytes in the brain due to the exchange between astrocytes and neurons that is disturbed during Huntington disease, a fatal neurodegenerative disease characterized by loss of voluntary motor control, psychiatric disturbances, and cognitive decline.

A new road map highlights how to overcome barriers to integrating person-centered care and evidence-based research at hospitals caring for vulnerable populations.

Current screening criteria for lung cancer risk assessments often miss a large proportion of cases. Research suggests that a panel of circulating protein biomarkers may improve lung cancer risk assessment and may be used to define eligibility for computed tomography screening.

Interest groups representing drug companies, patients, providers, and health plans all submitted comments to a Request for Information on the Trump administration blueprint for controlling drug prices and out-of-pocket costs.

Residents of the 20 Republican-led states that are challenging the Affordable Care Act (ACA)'s protections for people with preexisting medical conditions have the most to lose; House Ways and Means Committee Chairman Kevin Brady, R-Texas, is in talks with HHS about ways to restart ACA payments; Judge Brett M. Kavanaugh ruled in a case that paved the way for hospitals to seek more money from Medicare.

A phase 2 trial evaluated the safety and efficacy of quizartinib in patients with relapsed/refractory acute myeloid leukemia (AML), compared with salvage chemotherapy.

The shift to value-based care has stalled since 2017, according to a survey of health plan executive and providers commissioned by Quest Diagnostics. Quest said its third annual study suggests that physicians need better tools, like data access, and less complex quality measures to spur adoption of value-based healthcare, which focuses on care quality and patient outcomes rather than the quantity of services delivered.

The White House released a report saying the time is right to impose work requirements on 3 noncash welfare programs—food stamps, housing assistance, and Medicaid. Adding work requirements to these programs would reduce dependency upon them by nondisabled, working-age beneficiaries receiving such assistance, as poverty as fallen since the programs were created.

Quality measurement has been around for nearly 2 decades and in that time measures have evolved and also proliferated to the point of placing considerable burden on physicians and health systems. New efforts are being made to streamline current measures, fill in gaps, and harmonize measures across programs.

Acute myeloid leukemia can often appear suddenly in patients, without any detectable early symptoms. However, new research has identified the origins of AML, which can be detectable more than 5 years before the disease develops.

Kaiser Permanente and Geisenger Health Systems are leading the way towards using health records for medical studies and data mining that could help improve individual care; more than 7000 people on Arkansas' Medicaid expansion didn't meet a requirement that they report at least 80 hours of work in June; Novartis' relationship with Michael Cohen, President Donald Trump’s longtime lawyer, was “longer and more detailed” than the company has said, according to a Senate report.

Consumption of fast foods—especially hamburgers—3 or more times per week was more likely to be associated with severe asthma when compared with the consumption of fast foods only 1 to 2 times per week.

A study found that hospitals participating in Medicare’s Bundled Payments for Care Improvement and hospitals not participating are dissimilar in meaningful ways that limit the generalizability of the program's results.

Homozygous familial hypercholesterolemia is a rare genetic condition that is often characterized by an increased risk of premature cardiovascular (CV) events and cardiac death. Lomitapide decreases low-density lipoprotein cholesterol (LDL-C) levels, but there is little research of the effects on LDL-C goals and CV events.

Recently, 2 studies investigated pain experienced in patients with multiple sclerosis and how the disease is treated, overall.

The Institute for Clinical and Economic Review (ICER) has released their final evidence report evaluating the effectiveness and value of calcitonin gene-related peptide (CGRP) inhibitors as preventive treatments for patients who suffer from episodic or chronic migraine.

A recent study found that patients with chronic lung conditions such as chronic obstructive pulmonary disease are more likely to be physically active when they have regular contact with healthcare professionals, support from peers, and access to organized exercise sessions.

Since 1990, MANNA has been providing nourishing meals and a sense of community to people living with HIV and other chronic diseases in Philadelphia.

A study of the Mediterranean diet showed it had some beneficial effect on bone health for people with osteoporosis, but had no effect otherwise.

Although acute respiratory infections (ARIs) are often caused by viruses for which antibiotics are not effective, antibiotics remain commonly prescribed for ARIs.

Here are 5 of Supreme Court nominee Judge Brett Kavanaugh’s opinions on heavily debated healthcare topics.

CMS Administator Seema Verma said the changes are designed to reduce administrative burdens for physicians so they can spend more time with patients. A group representing community oncologists said a reimbursement change for new drugs could have unintended consequences.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

The FDA is planning a task force to find ways to combat drug shortages; a new Gallup poll finds nearly two-thirds of Americans support Roe v Wade 64% to 28%; the agency overseeing Oregon's legal medical marijuana industry conceded in a report it has not provided effective oversight of growers and others in the industry.

This week, the top managed care stories included additional moves by the Trump administration to unravel the Affordable Care Act; Pfizer canceled a round of drug price increases after speaking to the president; advocates for 340B sound the alarm on efforts to reform the program.

Through a smartphone app, SensorRx is utilizing patient-collected data and linking it to the patient’s electronic health record, allowing the physician to better understand a patient’s migraine trends and improve outcomes.

Providers, payers, and patients looking to do research on a clinical guideline need to get busy: They only have this weekend to download thousands of pages from federally funded websites that will close due to federal budget cuts in President Donald Trump’s budget.

Psychological stress and emotional well-being are important targets for multiple sclerosis (MS) research and clinical care. Mood disorders can adversely impact functioning, quality of life, and treatment adherence, and increase the risk of suicide.

There is widespread variation in how commercial insurers cover specialty drugs, a recent Heath Affairs study found, with only 16% of the drug-indication pairs examined covered the same way. Fewer than half were covered consistently by at least 75% of the plans.