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“These are times of unprecedented and unimaginable challenges for our health care system."

By 2030, heart failure—which tops the list of reasons for hospitalization among individuals older than 65 years—could tax the healthcare system $69.8 billion each year. Study results show the success of palliative care at reducing both healthcare costs and hospitalization.

In patients with hypertension who are overweight or moderately obese, diuretics were shown to potentially reduce the severity of obstructive sleep apnea, according to study findings.

As the COVID-19 pandemic upends daily life and economies across the globe, investigators are hurrying to test and develop potential treatments for the coronavirus, with some showing promise and others being ruled out.

Worries grow as officials prepare to stem the spread of coronavirus among the nation’s homeless population; the American College of Physcians launched a new telemedicine guide; a study found the human papillomavirus (HPV) vaccine, in addition to chemotherapy, may help treat cervical cancer.

Researchers found a frequent association of depression with psoriasis and atopic dermatitis, according to a descriptive-explorative and retrospective study published in Psychiatry Investigation.

In a webinar moderated by Thomas Parry, PhD, president of the Integrated Benefits Institute, an employer panel discussed value, application, and barriers to strategies involving the integration of employee needs and interests into benefit programs.

The severity of oro-dental anomalies in patients with Loeys-Dietz syndrome segregates by gene mutations, according to a study published in the Journal of Medical Genetics.

Amazon has decided to suspend nonessential item shipments; study results show patients with chronic obstructive pulmonary disease (COPD) benefited from a fluticasone furoate/umeclidinium/vilanterol combination inhaler; disruptions from the coronavirus now extend to proposed mergers among industry giants.

The number of US adults at high risk for vision loss increased from 2002 to 2017, according to an observational study based on national survey data.

The Trump administration asked Congress for billions in COVID-19 assistance for Americans while a report said government responses in both the United States and the United Kingdom were suddenly being influenced by a grim analysis forecasting half a million to over 2 million deaths if the virus is allowed to run rampant without nonpharmaceutical interventions—ie, social isolation.

The temporary relaxation and expansion of CMS' telehealth rules, which allows the use of methods like FaceTime and Skype, is aimed at protecting both older patients and their providers from COVID-19, which has led to curfews, shuttered schools, deserted Main Streets, and ravaged financial markets.

Propionic acid, a short-chain fatty acid, influences the multiple sclerosis (MS) disease course by an immunomodulatory mechanism, according to a study published in Cell.

Magnetic resonance imaging (MRI) scans of patients with vestibular migraine reveal abnormalities in the central vestibular cortex, according to a study published in Brain and Behavior.

Exposure to air pollutants alters the composition of gut microbiota, which increases the risk of obesity, diabetes, gastrointestinal disorders, and other chronic illnesses, according to a study published in Environment International.

In adolescent patients with sickle cell disease, hydroxycarbamide therapy was associated with improvements in neurocognition variables such as working memory, verbal memory, and nonverbal IQ, according to study findings.

Adolescents who have had family members deported or detained were linked with poor psychological outcomes; AstraZeneca's phase 3 CASPIAN trial failed to meet its primary endpoint; tips on how to destress when you feel overwhelmed.

A special, noncontact boxing program was shown to potentially improve quality-of-life (QOL) and likelihood of exercise among patients with Parkinson disease compared with those who did not participate, according to preliminary study findings originally to be presented at the American Academy of Neurology’s 72nd Annual Meeting.

Michael D. Abramoff, MD, PhD, is the Robert C. Watzke, MD Professor of ophthalmology and visual sciences at the University of Iowa Carver College of Medicine. He is also a professor of electrical and computer engineering and a professor of biomedical engineering at the University of Iowa. Abramoff’s research interests include how autonomous artificial intelligence (AI) can be used to improve the lives of patients, with a focus on autonomous AI-based diagnostic and quantification algorithms for retinal disease. He is the founder and executive chairman of IDx Technologies, which developed IDx-DR, an FDA-authorized autonomous AI diagnostic system for the detection of diabetic retinopathy and macular edema. An editor from The American Journal of Managed Care® recently conducted a question-and-answer session with Abramoff regarding the use of AI in the diagnosis of diabetic retinopathy.

Metastatic disease is the leading cause of death in the over 600,000 individuals worldwide who die of breast cancer each year. A new blood-based assay to detect minimal residual disease (MRD) in patients with stage 0 to 3 breast cancer was shown to have 100-fold greater sensitivity compared with digital droplet polymerase chain reaction.

pharmacytimes.org/on-demand/a-managed-care-review-of-unmet-medical-needs-new-treatments-and-health-economics-associated-with-schizophrenia-supplement

If you have a primary care relationship, there is at least one health care provider who does know you: your primary care physician (PCP). Yet in the turmoil of admission and the danger of discharge, it has often been likely that the only physician on earth who knows you and your health would never know that you spent 3 days in the hospital. That is, until you recovered and told the person.

While the cell and gene therapies approved so far are indicated for rare diseases with small patient populations, the successes of chimeric antigen receptor-T (CAR-T) therapies and expanding interest from biopharma stress the need to rapidly scale the supply chain as these therapies move toward commercial availability for more disease states and larger patient populations.

Children were found to exhibit distinct type 1 diabetes endotypes compared with older adolescents; DNA testing has shown to be beneficial but controversial when personlizing care for patients with breast cancer; artifical intelligence (AI) usage across healthcare.

The association of HIV infection with cardiovascular disease was particularly strong for heart failure and stroke.

Platelet indices may be altered in chronic obstructive pulmonary disease and therefore act as a valuable diagnostic marker, according to research.

Men demonstrated higher levels of respiratory events and more periodic limb movements but women had significantly higher levels of sleep-associated complaints across all measures.

Harvard's Ashish Jha, MD, MPH, was senior author on a popular 2015 paper that addressed care fragmentation among those with chronic illness.

Changes in brain tissue iron relate to poorer cognition in Parkinson disease, according to a recent study.