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The paper appeared a few months before the EMPA-REG OUTCOME trial revealed the potential of a new drug class, the SGLT2 inhibitors, in preventing hospitalization for heart failure.

Expanding access to biosimilar pegfilgrastim (Ziextenzo) for patients at intermediate risk of febrile neutropenia and converting patients at high risk who are on the reference product (Neulasta) could save millions in healthcare costs, according to new study results.

New data suggests white patients who are deficient in vitamin D have lower rates of survival when diagnosed with multiple myeloma. The phenomenon was not seen, however, in African American patients.

A new report on 3 rare cases of patients with myeloproliferative neoplasms who developed T-cell malignancies sheds light on red flags clinicians should look for.

Testing will now be possible for those who cannot get to a collection center, including those who are home because they are ill, quarantined, or at high risk of infection due to their age or comorbidities. A Rutgers official said the new method will allow for a dramatic increase in the number of people who can be tested.

A new large-scale study of patients with myeloproliferative neoplasm finds they are at twice the risk of mortality from respiratory disease.

Nivolumab-based first-line treatment is highly effective in patients with early-stage unfavorable classic Hodgkin lymphoma, according to results from the Nivolumab and AVD in Early-Stage Unfavorable Classic Hodgkin Lymphoma trial published in JAMA Oncology.

Compared with tumors smaller than 8 mm among patients with hormone receptor (HR)-positive, ERBB2-positive (formerly HER2-positive) breast cancer, tumors between 8 and 10 mm benefited more from postoperative chemotherapy.

A proposed bevacizumab biosimilar, BE1040V, was found to be noninferior to its reference product (Avastin) in terms of efficacy for the treatment of metastatic colorectal cancer (mCRC), according to a study published in Clinical Therapeutics.

This week, the top managed care news included FDA grants emergency use authorization to COVID-19 treatment; dapagliflozin’s new approval breaks ground in SGLT2 competition; and AJMC® gets an inside look at how The Michael J. Fox Foundation is assisting the Parkinson community during the pandemic.

Loteprednol etabonate ophthalmic gel 0.38% (Lotemax SM) from Bausch & Lomb was found to have no meaningful impact on intraocular pressure or visual acuity when administered to patients post surgery, according to a review published in Clinical Drug Investigation.

Guidelines created by the American Academy of Dermatology (AAD) and the National Psoriasis Foundation (NPF) address care management and treatment options for patients with psoriasis in relation to the increased risk of developing inflammatory, cardiovascular, and metabolic conditions.

The average sleep recommended for an adolescent is 8 to 10 hours per night, but recent study results show sleep deprivation is a widespread concern among this age group.

Coverage of our peer-reviewed research and news reporting in the healthcare and mainstream press.

CMS announced a final payment notice for the 2021 coverage year; experts say children should be more well-represented in coronavirus disease 2019 (COVID-19) clinical trials; a new report predicts sharp increases in deaths of despair resulting from the pandemic.

The use of polysomnography (PSG) can aid researchers in further understanding the association between sleep disorders and migraine in children, according to a study published in the Journal of Medicine and Life.

A study published this week found that germline testing of pediatric and young adult patients with cancer demonstrates that some tumors have actionable genetic variants.

Close to 6 million individuals die every year as a direct result of sepsis infection, with a majority of these deaths occurring in low- and middle-income countries. The HIV-positive population in sub-Saharan Africa is disproportionately affected by this opportunistic infection.

The patients selected for bronchoscopic lung volume reduction were younger compared with those who were not, the investigators said.

Investigators found no statistically significant evidence associating rotavirus vaccinations with type 1 diabetes (T1D) in children, according to results from a large cohort study published in JAMA Pediatrics.

Coronavirus disease 2019 (COVID-19) has not affected Florida as much as previously thought; despite emergency use authorization, remdesivir distribution is confusing many; a CDC report meant to provide guidance on reopening the country will apparently not be released.

More than 20% of breast cancer survivors are severely affected by breast cancer–related lymphedema, with debilitating adverse effects that include depression, chronic pain, and recurrent skin infections—all affecting overall quality of life.

Incorporating yoga into a regular migraine treatment regimen may be superior to medication alone, according to study results published in Neurology, the medical journal of the American Academy of Neurology.

Lupin Pharmaceuticals Inc. (Lupin) announced positive results from its phase 3 trial assessing the efficacy and safety of secnidazole (Solosec) in female patients with trichomoniasis. Although trichomoniasis is common in the United States, the risk of being infected with the infection is nearly 10 times higher for African American women compared with non-Hispanic white women.

The FDA approved AstraZeneca’s Farxiga (dapagliflozin) for the treatment of heart failure with reduced ejection fraction (HFrEF) in adults with and without type 2 diabetes (T2D). It's the first SGLT2 inhibitor to gain this approval in what is expected to be the next front of competition in this game-changing drug class.

Levels of caffeine consumption and lower blood urate were both inversely associated with the risk of Parkinson disease, highlighting the benefit derived from sufficient levels of both components, according to study findings.

Investigators hope that an experimental test could detect the novel coronavirus at a much lower cost than current tests; the FDA has extended the action date for a chimeric antigen receptor (CAR) T-cell therapy application from Bristol Myers Squibb (BMS); engineering teams devise inexpensive ventilators for emergency use.

As the coronavirus disease 2019 pandemic causes employers nationwide to implement strategies to efficiently operate amid potential revenue loss, the National Alliance of Healthcare Purchaser Coalitions released a comprehensive plan for employers and plan sponsors to optimize the delivery of advanced primary care.

A new test, supported by an artificial intelligence (AI) algorithm, can detect glaucoma progression a year and a half earlier than widely used optical coherence tomography retinal imaging technology, according to a study published in Expert Review of Molecular Diagnostics.

More than 26 million individuals worldwide live with heart failure every day. Because the condition is irreversible, finding ways and treatments to remedy this damage has long been a goal of physician-researchers.