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Smoking history can both increase the risk of cancer and create a hypoxic environment within the body, leading to poor outcomes, including less-effective treatment, among patients who undergo radiotherapy.

Women with heart disease during their first pregnancy had a higher rate of maternal cardiac events and neonatal complications, especially if they also had pulmonary hypertension, according to study findings published in BMC Pregnancy and Childbirth. The study also identified factors that can predict which pregnant women with heart disease will develop heart failure.

Patients with systemic lupus erythematosus (SLE) may consider hydroxychloroquine essential to their treatment, but after the drug was identified as a potential therapy for coronavirus disease 2019 (COVID-19), patients with SLE experienced reduced access to the treatment, which could increase the risk of SLE flare.

Heart failure yields the greatest 5-year mortality risk for individuals newly diagnosed with type 2 diabetes (T2D) compared with any other heart or kidney diseases, according to a study published in Circulation: Cardiovascular Quality and Outcomes.

With more states reporting record numbers of new infections of coronavirus disease 2019 (COVID-19), the United States has surpassed 3 million confirmed cases; the Trump administration has notified the United Nations that it will be withdrawing from the World Health Organization (WHO); a new injectable given to patients every 2 months can protect against HIV better than the commonly used daily pill.

Racial, ethnic, and socioeconomic status disparities exist in uveal melanoma treatment and survival, according to a study published in JAMA Ophthalmology.

There are 3 key issues that, if addressed by Congress, can optimally assist medical groups and health systems dealing with financial struggles amid the pandemic. These include continued funding to the CARES Act Provider Relief Fund, reinstating the Medicare Accelerated and Advanced Payment program, and permanently lifting waivers on telehealth, said Jerry Penso, MD, MBA, president and CEO of the American Medical Group Association.

FDA has lifted a partial clinical hold on a phase 2 trial of a treatment for patients with relapsed or refractory (R/R) Hodgkin lymphoma from ADC Therapeutics. The trial of camidanlumab tesirine (Cami), an antibody drug conjugate that binds to CD25, is evaluating the safety and efficacy of the therapy and is intended to support the submission of a Biologics License Application to the FDA.

JNCCN is the official journal of the National Comprehensive Cancer Network, a group of cancer centers that develops treatment guidelines that are considered the “gold standard” for payers.

A 52-week interim analysis confirmed previous findings highlighting the benefits of ruxolitinib in patients with polycythemia vera (PV) who are resistant or intolerant to hydroxyurea. The full study findings with a 24-month follow-up are still to come.

Hospitalized patients with chronic obstructive pulmonary disease (COPD) were shown to be at greater risk of obstructive sleep apnea (OSA) and insomnia than those without COPD, with worse outcomes for in-hospital sleep quality and quantity also observed, according to study findings.

Between 2002 and 2015, data showed an increase in the percentage of intimate partner violence (IPV)–related emergency department claims paid by private insurance in the United States. This finding suggests the Affordable Care Act (ACA) may have increased women’s willingness and ability to seek medical attention for IPV-related injuries and disclose IPV as the source of the injuries, according to a study published in Women’s Health Issues.

A survey conducted among migraineurs in Genova, Italy, found that during the coronavirus disease 2019 (COVID-19) quarantine, patients experienced fewer migraine attacks and less pain but exhibited moderate levels of depression correlated to migraine burden.

Several novel tests for the coronavirus disease 2019 (COVID-19) are currently being manufactured, which aim to ameliorate the lag time between testing and results; health expert says that it is currently not possible to conduct contact tracing in Southern states amid the resurgence of COVID-19 cases; survey finds people older than 60 years were no more willing to adhere to social isolation and other preventive measures than younger people.

Patients with HIV who have been heavily treated but are failing their current regimen have few treatment options and are at risk of progressing to AIDS and death.

End-stage renal disease has long been one of the most expensive and debilitating conditions that affects Medicare beneficiaries. Not only does dialysis cost $90,000 a year—those awaiting a kidney transplant automatically qualify for Medicare—but the need to travel to a dialysis center multiple times a week disrupts employment and home life.

The explosive growth of telehealth seen in March 2020 continued unabated in April, claims data show.

In survivors of childhood cancer, early initiation of annual breast cancer screening with MRI, with or without mammography, may reduce breast cancer mortality by half or more, according to a study published in Annals of Internal Medicine.

Increased particulate matter exposure is associated with worse dry eye metrics, after adjusting for humidity, according to a study published in JAMA Ophthalmology. The study also found that humidity is positively associated with dry eye metrics, potentially due to the fact that higher humidity increases microbial growth and subsequent particulate matter size and mass.

Seven symptoms were identified as most predictive of early morning OFF periods (EMO) in patients with Parkinson disease, which may assist in understanding and managing potential determinants and negative health effects of EMO.

Individuals living with type 1 and type 2 diabetes (T1D and T2D, respectively) are at greater risk of bone fractures, according to a systematic review update published in Bone.

Self-isolation and potential exposure of the coronavirus disease 2019 (COVID-19) were spotlighted as notable issues affecting addiction management; hundreds of scientists have called for the World Health Organization (WHO) to revise recommendations on COVID-19 as they highlight the airborne properties of the virus; considering safety measures and other factors when exercising in public gyms.

Results showed that living in a disadvantaged neighborhood is associated with worse COPD-related individual-level outcomes.

A recent article in the Journal of Head and Face Pain outlines strategies for migraine treatment without face-to-face visits, and describes ways health insurance companies can remove barriers to migraine care during the coronavirus disease 2019 (COVID-19) pandemic.

Previously associated with elite controller status, having an inherent low viral reservoir is now possibly linked to individuals with chronic HIV infection who initiate treatment with antiretrovirals more than 6 months after becoming infected.

Results from the University of New South Wales appeared in the New England Journal of Medicine. The co-lead investigator said the results show the need for more treatment options in chronic kidney disease.

The patient guide explains 2 possible side effects, cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome, that need to be caught quickly in order to be reversible.

A new study that looked at a cohort of 58 patients with multiple myeloma (MM) who contracted COVID-19 found the disease itself does not appear to be linked with higher mortality when these individuals are hospitalized.

Authors hope that identifying knowledge gaps surrounding rare blood cancers, such as essential thrombocythemia and polycythemia vera, will inspire the science community to invest in new comprehensive research on how to properly diagnose and treat patients.

A study from Germany asked patients with multiple sclerosis (MS) about beliefs regarding immune treatments as well as their illness perceptions. Researchers sought to assess these beliefs to test the idea that they are closely connected to adherence behavior.